Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Campbell S. D. Roxburgh"'
Autor:
Kathryn A. F. Pennel, Phimmada Hatthakarnkul, Colin S. Wood, Guang-Yu Lian, Sara S. F. Al-Badran, Jean A. Quinn, Assya Legrini, Jitwadee Inthagard, Peter G. Alexander, Hester van Wyk, Ahmad Kurniawan, Umar Hashmi, Michael A. Gillespie, Megan Mills, Aula Ammar, Jennifer Hay, Ditte Andersen, Colin Nixon, Selma Rebus, David K. Chang, Caroline Kelly, Andrea Harkin, Janet Graham, David Church, Ian Tomlinson, Mark Saunders, Tim Iveson, Tamsin R. M. Lannagan, Rene Jackstadt, Noori Maka, Paul G. Horgan, Campbell S. D. Roxburgh, Owen J. Sansom, Donald C. McMillan, Colin W. Steele, Nigel B. Jamieson, James H. Park, Antonia K. Roseweir, Joanne Edwards
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Colorectal cancer (CRC) is a heterogenous malignancy underpinned by dysregulation of cellular signaling pathways. Previous literature has implicated aberrant JAK/STAT3 signal transduction in the development and progression of solid tumors. I
Externí odkaz:
https://doaj.org/article/3b63169b435447a19a5fb490ee037279
Autor:
Lydia Melissourgou-Syka, Michael A. Gillespie, Sean M. O'Cathail, Owen J. Sansom, Colin W. Steele, Campbell S. D. Roxburgh
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Vol 6, Iss 4, Pp 187-197 (2023)
Colorectal cancer (CRC) is the third most common malignancy across the globe and, despite advances in treatment strategies, survival rates remain low. Rectal cancer (RC) accounts for most of these cases, and traditional management strategies for adva
Externí odkaz:
https://doaj.org/article/8489cce57d0f48d292b136f85aaed0f1
Autor:
Nicholas A Bradley, Josh McGovern, Ross D Dolan, Allan M Golder, Campbell S D Roxburgh, Graeme J K Guthrie, Donald C McMillan
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0300038 (2024)
BackgroundLow skeletal muscle mass and density, as assessed by CT-body composition (CT-BC), are recognised to have prognostic value in non-cancer and cancer patients. The aim of the present study was to compare CT-BC parameters between non-cancer (ab
Externí odkaz:
https://doaj.org/article/e96a2d4512b54e009424cc2c7499d523
Autor:
Fiona A. Ross, James H. Park, David Mansouri, Emilie Combet, Paul G. Horgan, Donald C. McMillan, Campbell S. D. Roxburgh
Publikováno v:
BMC Gastroenterology, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Introduction The presence of inflammation is a key hallmark of cancer and, plays an important role in disease progression and survival in colorectal cancer (CRC). Calprotectin detected in the faeces is a sensitive measure of colonic inflamma
Externí odkaz:
https://doaj.org/article/40a7a3489fcb4154a596b27c63d49a59
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Colorectal cancer remains a significant cause of morbidity and mortality, even despite curative treatment. A significant proportion of patients present emergently and have poorer outcomes compared to elective presentations, independent of TN
Externí odkaz:
https://doaj.org/article/83d4d2ca2eac42c1a1d146f2f272c80f
Autor:
Catherine R. Hanna, Sean M. O’Cathail, Janet S. Graham, Mark Saunders, Leslie Samuel, Mark Harrison, Lynsey Devlin, Joanne Edwards, Daniel R. Gaya, Caroline A. Kelly, Liz-Anne Lewsley, Noori Maka, Paula Morrison, Louise Dinnett, Susan Dillon, Jacqueline Gourlay, Jonathan J. Platt, Fiona Thomson, Richard A. Adams, Campbell S. D. Roxburgh
Publikováno v:
Radiation Oncology, Vol 16, Iss 1, Pp 1-9 (2021)
Abstract Background Advances in multi-modality treatment of locally advanced rectal cancer (LARC) have resulted in low local recurrence rates, but around 30% of patients will still die from distant metastatic disease. In parallel, there is increasing
Externí odkaz:
https://doaj.org/article/868a94dd8de84d4ca5757841bb549fda
Autor:
Aliah M Alhayyan, Stephen T McSorley, Rachel J Kearns, Paul G Horgan, Campbell S D Roxburgh, Donald C McMillan
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0228580 (2020)
BACKGROUND/AIM:The magnitude of the postoperative systemic inflammatory response (SIR) is now recognised to be associated with both short and long-term outcomes in patients undergoing surgery for colon cancer. During such surgery, it is unclear wheth
Externí odkaz:
https://doaj.org/article/12b14fc7cd3343bbbb7dbff55ae5333c
Publikováno v:
Perioperative Medicine, Vol 7, Iss 1, Pp 1-7 (2018)
Abstract Background Both preoperative cardiopulmonary exercise test (CPET)-derived measures of fitness and postoperative C-reactive protein (CRP) concentrations are associated with complications following surgery for colorectal cancer. The aim of the
Externí odkaz:
https://doaj.org/article/7e21da71bced4fb0b997ab8032aaf46f
Autor:
Catherine R. Hanna, Sean M. O’Cathail, Janet S. Graham, Mark Saunders, Leslie Samuel, Mark Harrison, Lynsey Devlin, Joanne Edwards, Daniel R. Gaya, Caroline A. Kelly, Liz-Anne Lewsley, Noori Maka, Paula Morrison, Louise Dinnett, Susan Dillon, Jacqueline Gourlay, Jonathan J. Platt, Fiona Thomson, Richard A. Adams, Campbell S. D. Roxburgh
Publikováno v:
Radiation Oncology, Vol 16, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/c77f52c206394dd99ab532798ab8accd
Autor:
Jin K Kim, Michael R Marco, Campbell S D Roxburgh, Chin-Tung Chen, Andrea Cercek, Paul Strombom, Larissa K F Temple, Garrett M Nash, Jose G Guillem, Philip B Paty, Rona Yaeger, Zsofia K Stadler, Mithat Gonen, Neil H Segal, Diane L Reidy, Anna Varghese, Jinru Shia, Efsevia Vakiani, Abraham J Wu, Paul B Romesser, Christopher H Crane, Marc J Gollub, Leonard Saltz, J Joshua Smith, Martin R Weiser, Sujata Patil, Julio Garcia-Aguilar
Publikováno v:
The oncologist. 27(5)
Background Total neoadjuvant therapy (TNT) improves tumor response in locally advanced rectal cancer (LARC) patients compared to neoadjuvant chemoradiotherapy alone. The effect of TNT on patient survival has not been fully investigated. Materials and