Eplerenone for chronic central serous chorioretinopathy in patients with active, previously untreated disease for more than 4 months (VICI): a randomised, double-blind, placebo-controlled trial

Autor: Mohammed Alarbi, Raj Mukherjee, Steven Dodds, Usha Chakravarthy, Chris A Rogers, Niro Narendran, Ivy Samuel, Edward Hughes, Savita Madhusudhan, Archana Airody, Nicola Hawes, Susan M. Downes, Abigail Raguro, Julie Cloake, Haralabos Eleftheriadis, Mania Horani, Raisa-Marie Platt, Rosie A Harris, Geeta Menon, P. M. Lenfestey, Deepthy Menon, Jeanette Allison, Abby O’Connell, Qin Neville, Sobha Sivaprasad, Niral Karia, Salwa Abugreen, Catrin Watkins, Yit Yang, Joanne A. P. Wilson, Ajay Kotagiri, Karen Gillvray, Wei Sing Lim, Barnaby C Reeves, Francine Behar-Cohen, David H. W. Steel, Maria Edwards, Devanga Bhatia, Clare Bailey, Chris Brand, Ramandeep Chhabra, Manju Chandran, Rebecca Denham, Daniel Buttress, Martin McKibbin, Faruque Ghanchi, Natalie Nixon, Campbell Keir, James S Talks, Krystian Kisza, Sergio Pagliarini, Meena Karpoor, Yinka Osoba, Lucy Culliford, Stephen Turner, Kelly Haigh, Alison Grice-Holt, Angela J. Cree, Elridge Thompson, Violet Andrews, Suresh Thulasidharan, Stefanos Efraimidis, Rebecca Kaye, Richard Gale, Tunde Peto, Helen Griffiths, Sharon Criddle, Phillippa Hazlewood, Lucy Ellis, Linzi Randle, Zeid Madanat, Moin Mohamed, Maria Shipman, Simon P. Harding, Andrew J. Lotery, Samir Bellani

Publikováno v: Eye (Lond)
Lotery, A, Sivaprasad, S, O'Connell, A J, Harris, R A, Culliford, L A, Ellis, L A, Cree, A, Madhusudan, S, Behar-Cohen, F, Chakravarthy, U, Peto, T, Rogers, C A & Reeves, B C 2020, ' Eplerenone for chronic central serous chorioretinopathy in patients with active, previously untreated disease for more than 4 months (VICI) : a randomised, double-blind, placebo-controlled trial ', Lancet, vol. 395, no. 10220, pp. 294-303 . https://doi.org/10.1016/S0140-6736(19)32981-2
Lotery, A, Sivaprasad, S, O’Connell, A, Harris, R A, Culliford, L, Ellis, L, Cree, A, Madhusudhan, S, Behar-Cohen, F, Chakravarthy, U, Peto, T, Rogers, C A & Reeves, B C 2020, ' Eplerenone for chronic central serous chorioretinopathy in patients with active, previously untreated disease for more than 4 months (VICI): a randomised, double-blind, placebo-controlled trial ', The Lancet, vol. 395, no. 10220, pp. 294-303 . https://doi.org/10.1016/S0140-6736(19)32981-2

BackgroundIn chronic central serous chorioretinopathy (CSCR), fluid accumulates in the subretinal space. CSCR is a common visually disabling condition that develops in individuals up to 60 years of age, and there is no definitive treatment. Previous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6321105a5ab097ae1b95045fcf4a86fc
https://pubmed.ncbi.nlm.nih.gov/34089001