Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Campbell Jeffrey Allen"'
Autor:
Ramesha Chakk S, Jin-Hai Wang, Russell Stephen Stabler, Paul Weller, Bong F. Sanpablo, Armando G. Villaseñor, Campbell Jeffrey Allen, Tara Mirzadegan, Viola Bordunov, Chris Allen Broka, Patricia Takahara, James M. Kress, Michelle F. Browner, Keith A. M. Walker, Mary Welch
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:4741-4745
The introduction of 3-arylmethyl, 3-aryloxy and 3-arylthio moieties into a 6-methylsulfonylindole framework using rational drug design led to potent, selective COX-2 inhibitors having efficacy in a rat carrageenan air pouch model. Incorporation of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b4b4fb3a2267e70d53ca55e5ce32ea
https://doi.org/10.1016/j.bmcl.2004.06.075
https://doi.org/10.1016/j.bmcl.2004.06.075
Autor:
B. Lovejoy, Robert Than Hendricks, H. E. Van Wart, Robert L. Martin, Chris Allen Broka, Campbell Jeffrey Allen, C. Luong, S. Carr, Keith A. M. Walker, A. Welch, Michelle F. Browner
Publikováno v:
Nature Structural Biology. 6:217-221
The X-ray crystal structures of the catalytic domain of human collagenase-3 (MMP-13) and collagenase-1 (MMP-1) with bound inhibitors provides a basis for understanding the selectivity profile of a novel series of matrix metalloprotease (MMP) inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a262f3c64f47d5d060c21f15a1f39485
https://doi.org/10.1038/6657
https://doi.org/10.1038/6657
Publikováno v:
Tetrahedron Letters. 45:4073-4075
The direct 3-arylthiolation of 2-substituted indoles using phenyliodine(III)bis trifluoroacetate (PIFA) in (CF3)2CHOH with a wide variety of benzenethiols has been accomplished. In particular, indoles bearing a 6-MeSO2 and either a 2-methyl or 2-carb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac93ee5f651f2702d457c3b8c4549398
https://doi.org/10.1016/j.tetlet.2004.03.153
https://doi.org/10.1016/j.tetlet.2004.03.153
Autor:
J. W. Dankwardt, Robert Than Hendricks, Keith A. M. Walker, Chris Allen Broka, James M. Kress, Jin-Hai Wang, Viola Bordunov, Campbell Jeffrey Allen
Publikováno v:
ChemInform. 35
The 3-arylmethylation of indoles using TMSOTf/Et 3 SiH with a wide variety of substituted benzaldehydes has been accomplished. Under these mild Lewis acid mediated reductive conditions, it was demonstrated that indoles bearing both 6-MeSO 2 and 2-met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be011f9c8d0873f0a1afd80401d8641b
https://doi.org/10.1002/chin.200434125
https://doi.org/10.1002/chin.200434125
Autor:
Campbell Jeffrey Allen, Robert Than Hendricks, Chris Allen Broka, J. W. Dankwardt, Jin-Hai Wang, Keith A. M. Walker, James M. Kress, Viola Bordunov
Publikováno v:
Tetrahedron Letters. 45:4587
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adeb71350a87612d0ba5759ffc1d92a8
https://doi.org/10.1016/j.tetlet.2004.04.060
https://doi.org/10.1016/j.tetlet.2004.04.060