Výsledky vyhledávání - "Campbell, Craig I."

Akademický článek

Mammary tumors that become independent of the type I insulin-like growth factor receptor express elevated levels of platelet-derived growth factor receptors

Autor: Campbell Craig I, Moorehead Roger A

Publikováno v: BMC Cancer, Vol 11, Iss 1, p 480 (2011)

Abstract Background Targeted therapies are becoming an essential part of breast cancer treatment and agents targeting the type I insulin-like growth factor receptor (IGF-IR) are currently being investigated in clinical trials. One of the limitations

Externí odkaz: https://doaj.org/article/0ebb43083b424ef3bf8d0de699235c05

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Akademický článek

Murine mammary tumor cells with a claudin-low genotype

Autor: Siwicky Megan D, Thompson Devan E, Campbell Craig I, Moorehead Roger A

Publikováno v: Cancer Cell International, Vol 11, Iss 1, p 28 (2011)

Abstract Background Molecular classification of human breast cancers has identified at least 5 distinct tumor subtypes; luminal A, luminal B, Her2-enriched, basal-like and claudin-low. The claudin-low subtype was identified in 2007 and is characteriz

Externí odkaz: https://doaj.org/article/52e27a5cbfef4ef691ac39423809629b

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Akademický článek

ErbB2 enhances mammary tumorigenesis, oncogene-independent recurrence and metastasis in a model of IGF-IR-mediated mammary tumorigenesis

Autor: Campbell Craig I, Petrik James J, Moorehead Roger A

Publikováno v: Molecular Cancer, Vol 9, Iss 1, p 235 (2010)

Abstract Background The type I insulin-like growth factor receptor (IGF-IR) and ErbB2 (Her-2) are receptor tyrosine kinases implicated in human breast cancer. Both proteins are currently the subject of targeted therapeutics that are used in the treat

Externí odkaz: https://doaj.org/article/87693421dce342a684fc50d2fd88d7cf

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