The ghrelin O-acyltransferase structure reveals a catalytic channel for transmembrane hormone acylation

Autor: Campaña, Maria B., Irudayanathan, Flaviyan Jerome, Davis, Tasha R., McGovern-Gooch, Kayleigh R., Loftus, Rosemary, Ashkar, Mohammad, Escoffery, Najae, Navarro, Melissa, Sieburg, Michelle A., Nangia, Shikha, Hougland, James L.

Publikováno v: In Journal of Biological Chemistry 27 September 2019 294(39):14166-14174

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PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation.

Autor: Campaña MB; Department of Craniofacial Biology, School of Dental Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Perkins MR; Department of Craniofacial Biology, School of Dental Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., McCabe MC; Department of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Neumann A; Department of Craniofacial Biology, School of Dental Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Larson ED; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Fantauzzo KA; Department of Craniofacial Biology, School of Dental Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Dec 27. Date of Electronic Publication: 2023 Dec 27.