Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Camilo Duque Velasquez"'
Autor:
Allen Herbst, Pamela Banser, Camilo Duque Velasquez, Charles E Mays, Valerie L Sim, David Westaway, Judd M Aiken, Debbie McKenzie
Publikováno v:
PLoS Pathogens, Vol 9, Iss 11, p e1003755 (2013)
Prion diseases are driven by the strain-specific, template-dependent transconformation of the normal cellular prion protein (PrP(C)) into a disease specific isoform PrP(Sc). Cell culture models of prion infection generally use replicating cells resul
Externí odkaz:
https://doaj.org/article/57fef16d1b224c51bbf0b2c065429b01
Publikováno v:
Cell and tissue research.
Chronic wasting disease (CWD) strains present a novel challenge to defining and mitigating this contagious prion disease of deer, elk, moose, and reindeer. Similar to strains of other prion diseases (bovine spongiform encephalopathy, sheep scrapie),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e932f442dae009355a933053e853283
https://pubmed.ncbi.nlm.nih.gov/36201049
https://pubmed.ncbi.nlm.nih.gov/36201049
Publikováno v:
Veterinary Research, Vol 52, Iss 1, Pp 1-13 (2021)
Abstract The spread of chronic wasting disease (CWD) during the last six decades has resulted in cervid populations of North America where CWD has become enzootic. This insidious disease has also been reported in wild and captive cervids from other c
Externí odkaz:
https://doaj.org/article/828a55db30f643ee8d64f9fe9ac2db89
Autor:
Debbie McKenzie, Camilo Duque-Velasquez, Joshua P. Vanderloo, Chad J. Johnson, Allen Herbst, Rick Chappell, Phil Bochsler
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 3, p e17450 (2011)
PLoS ONE, Vol 6, Iss 3, p e17450 (2011)
Analysis of the PRNP gene in cervids naturally infected with chronic wasting disease (CWD) suggested that PRNP polymorphisms affect the susceptibility of deer to infection. To test this effect, we orally inoculated 12 white-tailed deer with CWD agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::966b0240f72fd3333480739df3a663f3
http://europepmc.org/articles/PMC3060816
http://europepmc.org/articles/PMC3060816
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract PrPC variation at residue 96 (G/S) plays an important role in the epidemiology of chronic wasting disease (CWD) in exposed white-tailed deer populations. In vivo studies have demonstrated the protective effect of serine at codon 96, which hi
Externí odkaz:
https://doaj.org/article/feabaed0ca0c469995e0ee56a430bf75
Autor:
Samia Hannaoui, Elizabeth Triscott, Camilo Duque Velásquez, Sheng Chun Chang, Maria Immaculata Arifin, Irina Zemlyankina, Xinli Tang, Trent Bollinger, Holger Wille, Debbie McKenzie, Sabine Gilch
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009795 (2021)
Chronic wasting disease (CWD) is a prion disease affecting cervids. Polymorphisms in the prion protein gene can result in extended survival of CWD-infected animals. However, the impact of polymorphisms on cellular prion protein (PrPC) and prion prope
Externí odkaz:
https://doaj.org/article/67269ba71d934411b6886e1c0705445f
Autor:
Alicia Otero, Camilo Duque Velásquez, Chad Johnson, Allen Herbst, Rosa Bolea, Juan José Badiola, Judd Aiken, Debbie McKenzie
Publikováno v:
BMC Veterinary Research, Vol 15, Iss 1, Pp 1-14 (2019)
Abstract Background Chronic wasting disease (CWD) is a prion disease affecting members of the Cervidae family. PrPC primary structures play a key role in CWD susceptibility resulting in extended incubation periods and regulating the propagation of CW
Externí odkaz:
https://doaj.org/article/87d0127f21a94f0e80cf1027c9919bff
Autor:
Leonardo M Cortez, Satish K Nemani, Camilo Duque Velásquez, Aishwarya Sriraman, YongLiang Wang, Holger Wille, Debbie McKenzie, Valerie L Sim
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009703 (2021)
Prion diseases are transmissible neurodegenerative disorders that affect mammals, including humans. The central molecular event is the conversion of cellular prion glycoprotein, PrPC, into a plethora of assemblies, PrPSc, associated with disease. Dis
Externí odkaz:
https://doaj.org/article/6edcb27cf26947098ac2592983bba0b0
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Emerging Infectious Diseases, Vol 23, Iss 9, Pp 1598-1600 (2017)
Human and mouse prion proteins share a structural motif that regulates resistance to common chronic wasting disease (CWD) prion strains. Successful transmission of an emergent strain of CWD prion, H95+, into mice resulted in infection. Thus, emergent
Externí odkaz:
https://doaj.org/article/f6aa8f4422c74963836716f09d32d671