Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Camilo A. Ruiz"'
Autor:
Filipa Mota, Camilo A. Ruiz-Bedoya, Elizabeth W. Tucker, Daniel P. Holt, Patricia De Jesus, Martin A. Lodge, Clara Erice, Xueyi Chen, Melissa Bahr, Kelly Flavahan, John Kim, Mary Katherine Brosnan, Alvaro A. Ordonez, Charles A. Peloquin, Robert F. Dannals, Sanjay K. Jain
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Pretomanid has been approved for use in cases of multi-drug resistant pulmonary tuberculosis, yet the penetration of this antibiotic into other target tissues is not well established. Authors provide insight on pretomanid pharmacokinetics in the cent
Externí odkaz:
https://doaj.org/article/f0a782321c4e4e36aa37ab969660b2e2
Autor:
Stefanie Krug, Pankaj Prasad, Shiqi Xiao, Shichun Lun, Camilo A. Ruiz-Bedoya, Mariah Klunk, Alvaro A. Ordonez, Sanjay K. Jain, Geetha Srikrishna, Igor Kramnik, William R. Bishai
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Despite numerous advances in tuberculosis (TB) drug development, long treatment durations have led to the emergence of multidrug resistance, which poses a major hurdle to global TB control. Shortening treatment time therefore remains a top p
Externí odkaz:
https://doaj.org/article/9fc61409554c448b9963038eb9559826
Autor:
Camilo A. Ruiz-Beltrán, Adrián Romero-Garcés, Martín González-García, Rebeca Marfil, Antonio Bandera
Publikováno v:
Sensors, Vol 23, Iss 17, p 7491 (2023)
One of the main challenges faced by iris recognition systems is to be able to work with people in motion, where the sensor is at an increasing distance (more than 1 m) from the person. The ultimate goal is to make the system less and less intrusive a
Externí odkaz:
https://doaj.org/article/99a5788a8e6846e296eeb255c73b6cb0
Autor:
Camilo A. Ruiz-Bedoya, Filipa Mota, Elizabeth W. Tucker, Farina J. Mahmud, Maria I. Reyes-Mantilla, Clara Erice, Melissa Bahr, Kelly Flavahan, Patricia de Jesus, John Kim, Catherine A. Foss, Charles A. Peloquin, Dima A. Hammoud, Alvaro A. Ordonez, Carlos A. Pardo, Sanjay K. Jain
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 6 (2022)
Tuberculous meningitis (TB meningitis) is the most severe form of tuberculosis (TB), requiring 12 months of multidrug treatment for cure, and is associated with high morbidity and mortality. High-dose rifampin (35 mg/kg/d) is safe and improves the ba
Externí odkaz:
https://doaj.org/article/60a8e9fb510a41cda1c8b3797413d48b
Autor:
Alvaro A. Ordonez, Matthew F.L. Parker, Robert J. Miller, Donika Plyku, Camilo A. Ruiz-Bedoya, Elizabeth W. Tucker, Justin M. Luu, Dustin A. Dikeman, Wojciech G. Lesniak, Daniel P. Holt, Robert F. Dannals, Lloyd S. Miller, Steven P. Rowe, David M. Wilson, Sanjay K. Jain
Publikováno v:
JCI Insight, Vol 7, Iss 1 (2022)
Tools for noninvasive detection of bacterial pathogens are needed but are not currently available for clinical use. We have previously shown that para-aminobenzoic acid (PABA) rapidly accumulates in a wide range of pathogenic bacteria, motivating the
Externí odkaz:
https://doaj.org/article/5177739448e9442882f49a5d260f8ffe
Autor:
Oren Gordon, Mary Katherine Brosnan, Steve Yoon, Dawoon Jung, Kirsten Littlefield, Abhinaya Ganesan, Christopher A. Caputo, Maggie Li, William R. Morgenlander, Stephanie N. Henson, Alvaro A. Ordonez, Patricia De Jesus, Elizabeth W. Tucker, Nadine Peart Akindele, Zexu Ma, Jo Wilson, Camilo A. Ruiz-Bedoya, M. Elizabeth M. Younger, Evan M. Bloch, Shmuel Shoham, David Sullivan, Aaron A.R. Tobian, Kenneth R. Cooke, Ben Larman, Jogarao V.S. Gobburu, Arturo Casadevall, Andrew Pekosz, Howard M. Lederman, Sabra L. Klein, Sanjay K. Jain
Publikováno v:
JCI Insight, Vol 7, Iss 2 (2022)
BACKGROUND While most children who contract COVID-19 experience mild disease, high-risk children with underlying conditions may develop severe disease, requiring interventions. Kinetics of antibodies transferred via COVID-19 convalescent plasma early
Externí odkaz:
https://doaj.org/article/dd0c2a9ab4b14dc49bfbf39f9343ac3a
Autor:
Santosh Dhakal, Camilo A. Ruiz-Bedoya, Ruifeng Zhou, Patrick S. Creisher, Jason S. Villano, Kirsten Littlefield, Jennie Ruelas Castillo, Paula Marinho, Anne E. Jedlicka, Alvaro A. Ordonez, Melissa Bahr, Natalia Majewska, Michael J. Betenbaugh, Kelly Flavahan, Alice R. L. Mueller, Monika M. Looney, Darla Quijada, Filipa Mota, Sarah E. Beck, Jacqueline Brockhurst, Alicia M. Braxton, Natalie Castell, Mitchel Stover, Franco R. D’Alessio, Kelly A. Metcalf Pate, Petros C. Karakousis, Joseph L. Mankowski, Andrew Pekosz, Sanjay K. Jain, Sabra L. Klein
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT In the coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), more severe outcomes are reported in males than in females, including hospitalizations and deaths. Animal models
Externí odkaz:
https://doaj.org/article/c26a3303ffd040088f12495ee7b31392
Autor:
Luis C. Vesga, Camilo A. Ruiz-Hernández, Jeimmy J. Alvarez-Jacome, Jonny E. Duque, Bladimiro Rincon-Orozco, Stelia C. Mendez-Sanchez
Publikováno v:
Scientia Pharmaceutica, Vol 90, Iss 2, p 24 (2022)
Although there are existing vaccines against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), new COVID-19 cases are increasing due to low immunization coverage and the emergence of new variants. For this reason, new drugs to treat and p
Externí odkaz:
https://doaj.org/article/a91d5e7c2e5e4ebea12aa7d084b54c52
Autor:
Oren Gordon, Robert J. Miller, John M. Thompson, Alvaro A. Ordonez, Mariah H. Klunk, Dustin A. Dikeman, Daniel P. Joyce, Camilo A. Ruiz-Bedoya, Lloyd S. Miller, Sanjay K. Jain
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 7 (2020)
Post-surgical implant-associated spinal infection is a devastating complication commonly caused by Staphylococcus aureus. Biofilm formation is thought to reduce penetration of antibiotics and immune cells, contributing to chronic and difficult-to-tre
Externí odkaz:
https://doaj.org/article/34d85bf2faa14181ad2ac4a82046df1a
Publikováno v:
mBio, Vol 10, Iss 5 (2019)
ABSTRACT Molecular imaging is an emerging technology that enables the noninvasive visualization, characterization, and quantification of molecular events within living subjects. Positron emission tomography (PET) is a clinically available molecular i
Externí odkaz:
https://doaj.org/article/71b60b8796034205b62ab70c7288aad2