PharmFrag: An Easy and Fast Multiplex Pharmacogenetics Assay to Simultaneously Analyze 9 Genetic Polymorphisms Involved in Response Variability of Anticancer Drugs

Autor: Régis Bouvet, Marie-Clémence Verdier, Yahya El Baroudi, Marie-Dominique Galibert, Véronique David, Sacha Schutz ‖, Camille Tron Tron

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2020, 21 (24), ⟨10.3390/ijms21249650⟩
International Journal of Molecular Sciences, 2020, 21 (24), ⟨10.3390/ijms21249650⟩
Volume 21
Issue 24
International Journal of Molecular Sciences, Vol 21, Iss 9650, p 9650 (2020)

Regarding several cytotoxic agents, it was evidenced that genetic polymorphisms in genes encoding enzymes involved in their metabolism are associated with higher risk of toxicity. Genotyping these genes before treatment is a valuable strategy to prev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::de0260fac7d679278906cc069dc8eb8c
https://hal.archives-ouvertes.fr/hal-03095713