Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Camille Michiels"'
Autor:
Grégory La Sala, Camille Michiels, Tim Kükenshöner, Tania Brandstoetter, Barbara Maurer, Akiko Koide, Kelvin Lau, Florence Pojer, Shohei Koide, Veronika Sexl, Laure Dumoutier, Oliver Hantschel
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
STAT3 is an attractive therapeutic target but its homology with other STAT proteins complicates the development of selective inhibitors. Here, the authors develop monobodies with high affinity and selectivity for STAT3 and show that they can interfer
Externí odkaz:
https://doaj.org/article/709f9a713ee849dc860cc5c099ffede8
Autor:
Daniel Schnepf, Pedro Hernandez, Tanel Mahlakõiv, Stefania Crotta, Meagan E Sullender, Stefan T Peterson, Annette Ohnemus, Camille Michiels, Ian Gentle, Laure Dumoutier, Celso A Reis, Andreas Diefenbach, Andreas Wack, Megan T Baldridge, Peter Staeheli
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0247738 (2021)
The commensal microbiota regulates susceptibility to enteric pathogens by fine-tuning mucosal innate immune responses, but how susceptibility to enteric viruses is shaped by the microbiota remains incompletely understood. Past reports have indicated
Externí odkaz:
https://doaj.org/article/d68b02450db24632b3ba2774fe30dfac
Autor:
Mélanie Gaignage, Xuhao Zhang, Julie Stockis, Olivier Dedobbeleer, Camille Michiels, Perrine Cochez, Laure Dumoutier, Pierre G. Coulie, Sophie Lucas
Publikováno v:
Cancer immunology, immunotherapy : CII, Vol. 00, no.00, p. 00 (2022)
Transmembrane protein GARP binds latent TGF-β1 to form GARP:(latent)TGF-β1 complexes on the surface of several cell types including Tregs, B-cells, and platelets. Upon stimulation, these cells release active TGF-β1. Blocking TGF-β1 activation by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65823b2185ada761050520ef685d8b53
https://hdl.handle.net/2078.1/258446
https://hdl.handle.net/2078.1/258446
Publikováno v:
Journal of cellular and molecular medicine, Vol. 00, no.00, p. 00 (2022)
A subset of cytokines triggers the JAK-STAT pathway to exert various functions such as the induction of inflammation and immune responses. The receptors for these cytokines are dimers/trimers of transmembrane proteins devoid of intracellular kinase a
Autor:
Emilie Hendrickx, Laure Dumoutier, Christophe Blanchetot, Paméla Chéou, Léna Puigdevall, Nicolas Dauguet, Camille Michiels, Perrine Cochez, Younes Achouri
Publikováno v:
The Journal of investigative dermatology, (2021)
Exacerbated IL-22 activity induces tissue inflammation and immune disorders such as psoriasis. However, because IL-22 is also essential for tissue repair and defense at barrier interfaces, targeting IL-22 activity to treat psoriasis bears the risk of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4201b4920121f852cbaef870cf066db2
https://hdl.handle.net/2078.1/248659
https://hdl.handle.net/2078.1/248659
Autor:
Tanel Mahlakõiv, Stefan T. Peterson, Laure Dumoutier, Ian E Gentle, Peter Staeheli, Celso A. Reis, Meagan E Sullender, Camille Michiels, Pedro P. Hernandez, Annette Ohnemus, Megan T. Baldridge, Stefania Crotta, Andreas Diefenbach, Andreas Wack, Daniel Schnepf
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0247738 (2021)
PLoS ONE
PloS one, Vol. 16, no.8, p. e0247738 (2021)
PLoS ONE
PloS one, Vol. 16, no.8, p. e0247738 (2021)
The commensal microbiota regulates susceptibility to enteric pathogens by fine-tuning mucosal innate immune responses, but how susceptibility to enteric viruses is shaped by the microbiota remains incompletely understood. Past reports have indicated
Autor:
Guy Warnier, Emilie Hendrickx, Perrine Cochez, Camille Michiels, Jean-Christophe Renauld, Laure Dumoutier, Nicolas Dauguet
Publikováno v:
The Journal of Investigative Dermatology, Vol. 137, no. 5, p. 1094-1103 (2017)
Expression of the chemokine receptor Ccr6 is shared by most IL-22–producing cells, and Ccr6-deficient mice showed decreased IL-22 production and skin inflammation upon IL-23 intradermal injections. To determine whether this observation might be ext
Autor:
Laure Dumoutier, Emilie Hendrickx, Jean-Christophe Renauld, Guy Warnier, Astrid Van Belle, Magali de Heusch, Bernhard Ryffel, Nicolas Dauguet, Camille Michiels, Dieudonnée Togbe, Pierre Coulie, Muriel M. Lemaire, Perrine Cochez
Publikováno v:
European Journal of Immunology. 46:1449-1459
IL-22 has a detrimental role in skin inflammatory processes, for example in psoriasis. As transcription factor, AhR controls the IL-22 production by several cell types (i.e. Th17 cells). Here, we analyzed the role of Ahr in IL-22 production by immune
Autor:
Jean-Christophe Renauld, Emilie Hendrickx, Pierre Coulie, Muriel M. Lemaire, Laure Dumoutier, Perrine Cochez, Camille Michiels, Astrid Van Belle
Publikováno v:
Cytokine. 76:99
IL-22 has a detrimental role in skin inflammatory processes, particularly in the imiquimod-induced psoriasis model. As transcription factor AhR controls IL-22 production by several cell types, we analyzed its role in IL-22 production by immune cells
Autor:
Guy Warnier, Laure Dumoutier, Muriel M. Lemaire, Perrine Cochez, Camille Michiels, Astrid Van Belle, Magali de Heusch, Emilie Hendrickx, Nicolas Dauguet, Jean-Christophe Renauld
Publikováno v:
Annales de Dermatologie et de Vénéréologie. 142:S291
AHR (Recepteur aux aryls hydrocarbures) est un facteur de transcription qui controle la production d’IL-22 par differents types cellulaires. Precedemment, nous avons mis en evidence le role deletere de l’IL-22 dans un modele de psoriasis induit p