Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Camille Lenoir"'
Autor:
Jean Terrier, Frédéric Gaspar, Pauline Gosselin, Olivier Raboud, Camille Lenoir, Victoria Rollason, Chantal Csajka, Caroline Samer, Pierre Fontana, Youssef Daali, Jean‐Luc Reny, for the OptimAT study group
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 12, Pp 1872-1883 (2023)
Abstract When used in real‐world conditions, substantial interindividual variations in direct oral anticoagulant (DOAC) plasma concentrations are observed for a given dose, leading to a risk of over‐ or under‐exposure and clinically significant
Externí odkaz:
https://doaj.org/article/1a99f15a9a8e4eef9631ce2e055ca3a6
Autor:
Frédéric Gaspar, Jean Terrier, Samantha Favre, Pauline Gosselin, Pierre Fontana, Youssef Daali, Camille Lenoir, Caroline Flora Samer, Victoria Rollason, Jean‐Luc Reny, Chantal Csajka, Monia Guidi
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 10, Pp 1541-1552 (2023)
Abstract This study aimed to characterize apixaban pharmacokinetics (PKs) and its variability in a real‐world clinical setting of hospitalized patients using a population PK (PopPK) approach. Model‐based simulations helped to identify factors tha
Externí odkaz:
https://doaj.org/article/12bfdd438de34a6eaf7cee9749ed2cb1
Autor:
Camille Lenoir, Amine Niederer, Victoria Rollason, Jules Alexandre Desmeules, Youssef Daali, Caroline Flora Samer
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 1, Pp 30-43 (2022)
Abstract Xenobiotics can interact with cytochromes P450 (CYPs), resulting in drug–drug interactions, but CYPs can also contribute to drug–disease interactions, especially in the case of inflammation, which downregulates CYP activities through pre
Externí odkaz:
https://doaj.org/article/38600a9c283f4bc5acebae5314d4db6b
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Available in-vitro and animal studies indicate that inflammation impacts cytochromes P450 (CYP) activity via multiple and complex transcriptional and post-transcriptional mechanisms, depending on the specific CYP isoforms and the nature o
Externí odkaz:
https://doaj.org/article/5ffe811d918f48c8af530e24354d6afd
Autor:
Caroline Flora Samer, Camille Lenoir, Amine Niederer, Jules Alexandre Desmeules, Victoria Rollason, Youssef Daali
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 1, Pp 30-43 (2022)
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 1, Pp 30-43 (2022)
Xenobiotics can interact with cytochromes P450 (CYPs), resulting in drug–drug interactions, but CYPs can also contribute to drug–disease interactions, especially in the case of inflammation, which downregulates CYP activities through pretranscrip
Publikováno v:
Clinical pharmacology and therapeutics.
Autor:
Jules Alexandre Desmeules, Yvonne Gloor, Caroline Flora Samer, Jean Terrier, Victoria Rollason, François Curtin, Camille Lenoir, Youssef Daali, Jean-Luc Reny
Publikováno v:
Clinical Pharmacology and Therapeutics
Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection, is a severe acute respiratory syndrome with an underlying inflammatory state. We have previously demonstrated that acute infl
Autor:
Camille Lenoir, Jules Alexandre Desmeules, Olivier Grosgurin, Myriam El Biali, Christophe Luthy, Victoria Rollason
Publikováno v:
International Journal of Clinical Pharmacy (2019)
Background Proton pump inhibitors are among the most widely prescribed drugs in the world, but more than half of the indications for prescription are unjustified. The misuse of this therapeutic class has heavy consequences such as additional health c
Publikováno v:
Journal of Personalized Medicine
Journal of Personalized Medicine, Vol 11, Iss 250, p 250 (2021)
Journal of Personalized Medicine, Vol 11, Iss 250, p 250 (2021)
Rivaroxaban has become an alternative to vitamin K antagonists, which are considered to be at higher risk of drug-drug interactions (DDI) and more difficult to use. However, DDI do occur. We systematically reviewed studies that evaluated them and ana
Publikováno v:
Pharmacology Research & Perspectives
Apixaban, a direct oral anticoagulant, has emerged over the past few years because it is considered to have a low risk of drug‐drug interactions compared to vitamin K antagonists. To better characterize these interactions, we systematically reviewe