Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Camille Guillard-Sirieix"'
Autor:
Ariadna Laguna, Núria Peñuelas, Marta Gonzalez-Sepulveda, Alba Nicolau, Sébastien Arthaud, Camille Guillard-Sirieix, Marina Lorente-Picón, Joan Compte, Lluís Miquel-Rio, Helena Xicoy, Jiong Liu, Annabelle Parent, Thais Cuadros, Jordi Romero-Giménez, Gemma Pujol, Lydia Giménez-Llort, Patrice Fort, Analia Bortolozzi, Iria Carballo-Carbajal, Miquel Vila
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract One key limitation in developing effective treatments for neurodegenerative diseases is the lack of models accurately mimicking the complex physiopathology of the human disease. Humans accumulate with age the pigment neuromelanin inside neur
Externí odkaz:
https://doaj.org/article/de9a8ae5677146419f7bcb8a1fa18b31
Autor:
Marta Gonzalez-Sepulveda, Joan Compte, Thais Cuadros, Alba Nicolau, Camille Guillard-Sirieix, Núria Peñuelas, Marina Lorente-Picon, Annabelle Parent, Jordi Romero-Giménez, Joana M Cladera-Sastre, Ariadna Laguna, Miquel Vila
Publikováno v:
Brain. 146:1040-1052
Humans accumulate with age the dark-brown pigment neuromelanin inside specific neuronal groups. Neurons with the highest neuromelanin levels are particularly susceptible to degeneration in Parkinson’s disease, especially dopaminergic neurons of the
Autor:
Marta Gonzalez-Sepulveda, Joan Compte, Thais Cuadros, Alba Nicolau, Camille Guillard-Sirieix, Núria Peñuelas, Marina Lorente-Picon, Annabelle Parent, Jordi Romero-Giménez, Joana M. Cladera-Sastre, Ariadna Laguna, Miquel Vila
Humans accumulate with age the dark-brown pigment neuromelanin inside specific neuronal groups. Neurons with the highest neuromelanin levels are particularly susceptible to degeneration in Parkinson’s disease, especially dopaminergic neurons of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c65f877cd357c6c7a4f7fe159ff79e76
https://doi.org/10.1101/2022.08.08.503142
https://doi.org/10.1101/2022.08.08.503142
Autor:
Camille Guillard-Sirieix, Iria Carballo-Carbajal, Jordi Galiano-Landeira, Helena Xicoy, Nuria Peñuelas, Annabelle Parent, Marta Gonzalez-Sepulveda, Thais Cuadros, Ariadna Laguna, Jordi Romero-Giménez, Jumpei Kobayashi, Alba Nicolau, Miquel Vila, Joan Compte
Publikováno v:
ACS chemical neuroscience. 11(17)
Dopamine is a key neurotransmitter in the pathophysiology of various neurological disorders such as addiction or Parkinson's disease. Disturbances in its metabolism could lead to dopamine accumulation in the cytoplasm and an increased production of o