Výsledky vyhledávání - "Camille Godon"

Kinetics of endogenous mouse FEN1 in base excision repair

Autor: Camille Godon, Arjan F. Theil, Pierre-Olivier Mari, Elisabeth Larsen, Guro Flor Lien, Liv Kleppa, Wim Vermeulen, Arne Klungland, Giuseppina Giglia-Mari, Hege Wiksen, Gaute Nesse

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2012, 40 (18), pp.9044-9059. ⟨10.1093/nar/gks673⟩
Nucleic Acids Research, 40(18), 9044-9059. Oxford University Press

The structure specific flap endonuclease 1 (FEN1) plays an essential role in long-patch base excision repair (BER) and in DNA replication. We have generated a fluorescently tagged FEN1 expressing mouse which allows monitoring the localization and kin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::739ffbdb04bfa08e73cfa88067d7b361
https://doi.org/10.1093/nar/gks673

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PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility

Autor: Janet Hall, Nicole Giocanti, Vincent Favaudon, Camille Godon, Frédérique Mégnin-Chanet, Fabrice P. Cordelières, Denis Biard

Publikováno v: Nucleic Acids Research

The consequences of PARP-1 disruption or inhibition on DNA single-strand break repair (SSBR) and radio-induced lethality were determined in synchronized, isogenic HeLa cells stably silenced or not for poly(ADP-ribose) polymerase-1 (PARP-1) (PARP-1(KD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8fc6726ec317f230682d6bae242340
https://doi.org/10.1093/nar/gkn403

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Radiosensitization by the poly(ADP-ribose) polymerase inhibitor 4-amino-1,8-naphthalimide is specific of the S phase of the cell cycle and involves arrest of DNA synthesis

Autor: Marie Fernet, Vincent Favaudon, Nicole Giocanti, Camille Godon, Georges Noël, Frédérique Mégnin-Chanet

Publikováno v: Molecular Cancer Therapeutics. 5:564-574

Radiosensitization caused by the poly(ADP-ribose) polymerase (PARP) inhibitor 4-amino-1,8-naphthalimide (ANI) was investigated in 10 asynchronously growing rodent (V79, CHO-Xrs6, CHO-K1, PARP-1+/+ 3T3, and PARP-1−/− 3T3) or human (HeLa, MRC5VI, I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c30261364b770749bdabf227ddd1c74a
https://doi.org/10.1158/1535-7163.mct-05-0418

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Generation of DNA single-strand displacement by compromised nucleotide excision repair

Autor: Camille, Godon, Sophie, Mourgues, Julie, Nonnekens, Amandine, Mourcet, Fréderic, Coin, Wim, Vermeulen, Pierre-Olivier, Mari, Giuseppina, Giglia-Mari

Publikováno v: EMBO Journal
EMBO Journal, EMBO Press, 2012, 31 (17), pp.3550-3563. ⟨10.1038/emboj.2012.193⟩
EMBO Journal, 31(17), 3550-3563. Wiley-Blackwell
The EMBO Journal
The EMBO Journal, 2012, 31 (17), pp.3550-3563. ⟨10.1038/emboj.2012.193⟩

Nucleotide excision repair (NER) is a precisely coordinated process essential to avoid DNA damage-induced cellular malfunction and mutagenesis. Here, we investigate the mechanistic details and effects of the NER machinery when it is compromised by a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::48241eb3c79aabea3f3d9d627c905903
https://hal.archives-ouvertes.fr/hal-02148344

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