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pro vyhledávání: '"Camille Georgaros"'
Autor:
Nidhi Gadhia, Rachel Weiss, Matthew Andisik, Susan C Irvin, Tiffany Truong, Giane Sumner, Jessica-Ann Taylor, Andrew F. Dengler, Anne Paccaly, Albert Torri, Mohamed Hassanein, Michael A Partridge, Camille Georgaros
Publikováno v:
The AAPS Journal
Monoclonal antibodies (mAbs) are a leading class of biotherapeutics. In oncology, patients often fail on early lines of biologic therapy to a specific target. Some patients may then enroll in a new clinical trial with a mAb specific for the same targ
Autor:
Thomas DiCioccio, Nicholas J. Papadopoulos, Albert Torri, Thomas J. Daly, Giane Sumner, Camille Georgaros, Joel H. Martin, Ashique Rafique
Publikováno v:
Bioanalysis. 11:381-392
Aim: To evaluate the accuracy of the Quantikine Human VEGF Immunoassay (R&D Systems) in the presence of VEGF inhibitors. Materials & Methods: Quantikine VEGF ELISA (R&D), anti-VEGF165 mAb (R&D), VEGF165 and aflibercept (Regeneron), ranibizumab and be
Autor:
Camille Georgaros, Giane Sumner, Albert Torri, Elif Kabuloglu Karayusuf, Michael A Partridge, Gary Shyu
Publikováno v:
The AAPS Journal. 22
Neutralizing anti-drug antibody (NAb) assays often have lower drug tolerance (DT) than trough drug concentrations, potentially under-estimating NAb incidence. To improve DT, drug-specific proteins were coupled to magnetic beads to deplete drug in the