Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Camille C Gunderson"'
Autor:
Camille C Gunderson, Rangasudhagar Radhakrishnan, Rohini Gomathinayagam, Sanam Husain, Sheeja Aravindan, Kathleen M Moore, Danny N Dhanasekaran, Muralidharan Jayaraman
Publikováno v:
Biomarker Insights, Vol 17 (2022)
Clinical management of gynecological cancer begins by optimal debulking with first-line platinum-based chemotherapy. However, in ~80% patients, ovarian cancer will recur and is lethal. Prognostic gene signature panel identifying platinum-resistance e
Externí odkaz:
https://doaj.org/article/0780ba611363457ba4faf1e929ea766e
Autor:
Alessandro D. Santin, Virginia Filiaci, Stefania Bellone, Roisin O'Cearbhaill, Elena S. Ratner, Cara A. Mathews, Guilherme Cantuaria, Camille C. Gunderson, Teresa Rutledge, Barbara M. Buttin, Heather A. Lankes, Michael J. Birrer
Publikováno v:
Gynecologic Oncology Reports, Vol 33, Iss , Pp 100590- (2020)
Externí odkaz:
https://doaj.org/article/e36ae999e594477eabe4645d00fde7e6
Autor:
Alessandro D. Santin, Virginia Filiaci, Stefania Bellone, Elena S. Ratner, Cara A. Mathews, Guilherme Cantuaria, Camille C. Gunderson, Teresa Rutledge, Barbara M. Buttin, Heather A. Lankes, Michael Frumovitz, Samir N. Khleif, Warner K. Huh, Michael J. Birrer
Publikováno v:
Gynecologic Oncology Reports, Vol 31, Iss , Pp - (2020)
Purpose: NRG Oncology conducted a phase II trial to assess the antitumor activity and tolerability of copanlisib, a selective inhibitor of PIK3CA, in persistent or recurrent endometrial carcinoma harboring hotspot PIK3CA mutations. Patients and metho
Externí odkaz:
https://doaj.org/article/a9522c304829496fb1723dba30d15668
Autor:
D. Scott McMeekin, Robert Joseph Stagg, Rainer Karl Brachmann, Kathleen N. Moore, Paul Sabbatini, Gina Mantia-Smaldone, Azeez Farooki, Camille C. Gunderson, Roisin E. O'Cearbhaill, Robert A. Burger, Ann M. Kapoun, Mark A. Morgan
Publikováno v:
Ann Transl Med
Objectives The WNT pathway is an important oncologic driver of epithelial ovarian cancer (EOC). The first-in-class recombinant fusion protein ipafricept (IPA) blocks Wnt signaling through binding of Wnt ligands. This phase Ib trial was designed to de
Publikováno v:
Current Opinion in Obstetrics & Gynecology. 31:4-11
This review will provide an update of recently presented clinical data as well as discuss ongoing trials focused on the incorporation of poly (ADP-ribose) polymerase inhibitors (PARPi) into the treatment paradigm for ovarian cancer.As of this publica
Autor:
Katheleen Moore, Robert S. Mannel, Theresa C. Thai, Xuxin Chen, Yuchen Qiu, Hong Liu, Camille C. Gunderson, Bin Zheng
Publikováno v:
Biophotonics and Immune Responses XVI.
The purpose of this study is to develop a novel computer-aided diagnosis (CAD) scheme to facilitate breast mass classification, which is based on the latest transferring generative adversarial networks (GAN) technology. Although GAN is one of the mos
Autor:
Lisa Barroilhet, Linda R. Duska, Cynthia A. Sirard, Haider Mahdi, Kristopher Lybarger, William H. Bradley, Ursula A. Matulonis, Michael H. Kagey, Camille C. Gunderson, Howard M. Goodman, Erika Hamilton, Jasgit C. Sachdev, Adam C. ElNaggar, Michael J. Birrer, Cesar M. Castro, Rebecca C. Arend, David M. O'Malley
Publikováno v:
Gynecologic Oncology. 162:S16-S17
Objectives: Dickkopf-1 (DKK1) modulates Wnt signaling, promotes tumor growth through a CKAP4-AKT signaling pathway and contributes to an immune suppressive tumor microenvironment. DKN-01 (D), a neutralizing DKK1 antibody has demonstrated safety and c
Autor:
John W. Moroney, Joyce F. Liu, Xiaohong Liu, Gottfried E. Konecny, Elena Ratner, Rebecca C. Arend, Ping Wang, Oladapo Yeku, Elisabeth Diver, Andrea E. Wahner Hendrickson, Lena Evilevitch, Divya Gupta, Sarah Wang, Vivek Samnotra, Camille C. Gunderson, Stephanie Gaillard, Emeline Bacque, Joseph Tang
Publikováno v:
Gynecologic Oncology. 162:S17-S18
Objectives: Preclinical evidence suggests that PARP inhibition (PARPi), anti-PD-1 therapy, and anti-angiogenic therapies have interactions that may support synergistic antitumor activity in pts with PROC. This phase 2 study evaluated activity of comb
Autor:
Casey Cosgrove, Michael L. Pearl, Rahel G Ghebre, Steven E. Waggoner, Ian S. Hagemann, Saketh R. Guntupalli, David G. Mutch, Golnar Rasty, Camille C. Gunderson, Robert A. Soslow, Matthew A. Powell, Kay J. Park, Olga B. Ioffe, Richard J. Zaino, Wei Deng, Angeles Alvarez Secord, Shashikant Lele, Cara Mathews, Meenakshi Singh, William T. Creasman
Publikováno v:
Gynecol Oncol
Objective While most cases of endometrial cancer can readily be classified as pure endometrioid, pure serous, or another type, others show an apparent mixture of serous and endometrioid components, or indeterminate serous versus endometrioid features
Autor:
Lin Wang, Amy L. Kennedy, Satish Kumar Ramraj, Doris M. Benbrook, Yan D. Zhao, Camille C. Gunderson, Gopal Pathuri, Zitha Redempta Isingizwe, Suganthapriya Elayapillai, Lauri A. Hunsucker, Stanley Lightfoot, Magdalena Bieniasz
Publikováno v:
Gynecol Oncol
Objective Mebendazole and other anti-parasitic drugs are being used off-prescription based on social media and unofficial accounts of their anti-cancer activity. The purpose of this study was to conduct a controlled evaluation of mebendazole's therap