Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Camille, Soun"'
Autor:
Phyllis F. Cheung, JiaJin Yang, Rui Fang, Arianna Borgers, Kirsten Krengel, Anne Stoffel, Kristina Althoff, Chi Wai Yip, Elaine H. L. Siu, Linda W. C. Ng, Karl S. Lang, Lamin B. Cham, Daniel R. Engel, Camille Soun, Igor Cima, Björn Scheffler, Jana K. Striefler, Marianne Sinn, Marcus Bahra, Uwe Pelzer, Helmut Oettle, Peter Markus, Esther M. M. Smeets, Erik H. J. G. Aarntzen, Konstantinos Savvatakis, Sven-Thorsten Liffers, Smiths S. Lueong, Christian Neander, Anna Bazarna, Xin Zhang, Annette Paschen, Howard C. Crawford, Anthony W. H. Chan, Siu Tim Cheung, Jens T. Siveke
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Immune responses to pancreatic ductal adenocarcinoma can be inhibited by cancer cells. Here the authors show that high levels of progranulin in PDAC inhibits immune responses by reducing MHC class I antigen presentation through enhanced degradation o
Externí odkaz:
https://doaj.org/article/c9aa189db2194c2eba13f30f461a6fdd
Autor:
Jan-Malte Placke, Camille Soun, Jenny Bottek, Rudolf Herbst, Patrick Terheyden, Jochen Utikal, Claudia Pföhler, Jens Ulrich, Alexander Kreuter, Christiane Pfeiffer, Peter Mohr, Ralf Gutzmer, Friedegund Meier, Edgar Dippel, Michael Weichenthal, Lisa Zimmer, Elisabeth Livingstone, Jürgen C. Becker, Georg Lodde, Antje Sucker, Klaus Griewank, Susanne Horn, Eva Hadaschik, Alexander Roesch, Dirk Schadendorf, Daniel Robert Engel, Selma Ugurel
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundPD-1-based immune checkpoint blockade (ICB) is a highly effective therapy in metastatic melanoma. However, 40-60% of patients are primarily resistant, with valid predictive biomarkers currently missing. This study investigated the digitally
Externí odkaz:
https://doaj.org/article/967680da967d4d1da0a6265a5de347ab
Autor:
Johanna F. Scheunemann, Julia J. Reichwald, Patricia Jebett Korir, Janina M. Kuehlwein, Lea-Marie Jenster, Christiane Hammerschmidt-Kamper, Matthew D. Lewis, Katrin Klocke, Max Borsche, Kim E. Schwendt, Camille Soun, Stephanie Thiebes, Andreas Limmer, Daniel R. Engel, Ann-Kristin Mueller, Achim Hoerauf, Marc P. Hübner, Beatrix Schumak
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Cerebral malaria is a potentially lethal disease, which is caused by excessive inflammatory responses to Plasmodium parasites. Here we use a newly developed transgenic Plasmodium berghei ANKA (PbAAma1OVA) parasite that can be used to study parasite-s
Externí odkaz:
https://doaj.org/article/d731aa41bf42464ead8cc7486303f906
Autor:
Simon F. Merz, Sebastian Korste, Lea Bornemann, Lars Michel, Pia Stock, Anthony Squire, Camille Soun, Daniel R. Engel, Julia Detzer, Holger Lörchner, Dirk M. Hermann, Markus Kamler, Joachim Klode, Ulrike B. Hendgen-Cotta, Tienush Rassaf, Matthias Gunzer, Matthias Totzeck
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Detailed characterization of cardiac damage following ischemia/reperfusion injury and detection of occurring inflammatory responses is important for the development of new therapeutic concepts. Here the authors present a method for the three-dimensio
Externí odkaz:
https://doaj.org/article/3e96cf3e564a4e068419e2da632f2557
Autor:
Camille Soun, Stephanie Thiebes, Barbara Sitek, Denise Zwanziger, Judith-Mira Pohl, Julia K. Lill, Franziska Hoffmann, Oliver Hofnagel, Daniel R. Engel, Jenny Bottek, Ferdinand von Eggeling, Faikah Gueler, Robin Christ, Michael J. Hickey, Nirojah Subramaniam, Thilo Bracht
Publikováno v:
Kidney International. 100:349-363
Enterohaemorrhagic E. coli cause major epidemics worldwide with significant organ damage and very high percentages of death. Due to the ability of enterohaemorrhagic E. coli to produce shiga toxin these bacteria damage the kidney leading to the hemol
Autor:
Simon F. Merz, Sebastian Korste, Lea Bornemann, Lars Michel, Pia Stock, Anthony Squire, Camille Soun, Daniel R. Engel, Julia Detzer, Holger Lörchner, Dirk M. Hermann, Markus Kamler, Joachim Klode, Ulrike B. Hendgen-Cotta, Tienush Rassaf, Matthias Gunzer, Matthias Totzeck
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/d9923d29d593469cb22f223c62a1ff70
Autor:
Nirojah Subramaniam, Matthias Kudla, Camille Soun, Jan Dürig, Barbara Sitek, Jenny Bottek, Sven Brandau, Hans Christian Reinhardt, Stephanie Thiebes, Kirsten Bruderek, Thilo Bracht, Daniel R. Engel, Aaron Pfennig, Julia K. Lill, Patricia Johansson, Sven Rahmann, Kristina Zec, Elena de Dios Panal, Ralf Herrmann, Martina Seiffert
Publikováno v:
Blood Adv
Patients with chronic lymphocytic leukemia (CLL) typically suffer from frequent and severe bacterial infections. Although it is well known that neutrophils are critical innate immune cells facilitating the early defense, the underlying phenotypical a
Autor:
Jenny, Bottek, Camille, Soun, Julia K, Lill, Akanksha, Dixit, Stephanie, Thiebes, Anna-Lena, Beerlage, Marius, Horstmann, Annett, Urbanek, Heike, Heuer, Julian, Uszkoreit, Martin, Eisenacher, Thilo, Bracht, Barbara, Sitek, Franziska, Hoffmann, Nirojah, Vijitha, Ferdinand, von Eggeling, Daniel R, Engel
Publikováno v:
Mucosal Immunology
The urothelium of the urinary bladder represents the first line of defense. However, uropathogenic E. coli (UPEC) damage the urothelium and cause acute bacterial infection. Here, we demonstrate the crosstalk between macrophages and the urothelium sti
Autor:
Julia Detzer, Matthias Totzeck, Dirk M. Hermann, Lea Bornemann, Tienush Rassaf, Simon F. Merz, Anthony Squire, Camille Soun, Ulrike B. Hendgen-Cotta, Lars Michel, Pia Stock, Daniel R. Engel, Holger Lörchner, Sebastian Korste, Markus Kamler, Joachim Klode, Matthias Gunzer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
Nature Communications
Nature Communications
Cardioprotection by salvage of the infarct-affected myocardium is an unmet yet highly desired therapeutic goal. To develop new dedicated therapies, experimental myocardial ischemia/reperfusion (I/R) injury would require methods to simultaneously char
Autor:
Camille Soun, Stephanie Thiebes, Julia K. Volke, Julian Uszkoreit, Daniel R. Engel, Franziska Hoffmann, Nirojah Vijitha, Thilo Bracht, Ferdinand von Eggeling, Barbara Sitek, Martin Eisenacher, Akanksha Dixit, Marius Horstmann, Annett Urbanek, Jenny Bottek, Anna-Lena Beerlage
SUMMARYMacrophages perform essential functions during bacterial infections, such as phagocytosis of pathogens and elimination of neutrophils to reduce spreading of infection, inflammation and tissue damage. The spatial distribution of macrophages is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d969a291061efb57b3339c95b58c075