Cells on Hydrogels with Micron-Scaled Stiffness Patterns Demonstrate Local Stiffness Sensing

Autor: Abbas Mgharbel, Camille Migdal, Nicolas Bouchonville, Paul Dupenloup, David Fuard, Eline Lopez-Soler, Caterina Tomba, Marie Courçon, Danielle Gulino-Debrac, Héléne Delanoë-Ayari, Alice Nicolas

Publikováno v: Nanomaterials, Vol 12, Iss 4, p 648 (2022)

Cell rigidity sensing—a basic cellular process allowing cells to adapt to mechanical cues—involves cell capabilities exerting force on the extracellular environment. In vivo, cells are exposed to multi-scaled heterogeneities in the mechanical pro

Externí odkaz: https://doaj.org/article/c7affd6f09b24affaa9af06a045a0fc1

Polyacrylamide hydrogels with rigidity-independent surface chemistry show limited long-term maintenance of pluripotency of human induced pluripotent stem cells on soft substrates

Autor: Solenne Paiva, Camille Migdal, Alice Nicolas, Eline Lopez Soler, Yeranuhi Hovhannisyan, Onnik Agbulut, Pierre Joanne

Publikováno v: ACS Biomaterials Science and Engineering
ACS Biomaterials Science and Engineering, ACS, 2019, ⟨10.1021/acsbiomaterials.9b01189⟩
ACS Biomaterials Science and Engineering, 2019, ⟨10.1021/acsbiomaterials.9b01189⟩

In general, cells are cultured and adapted to the in vitro rigidities of plastic or glass ranging between 1 and 10 GPa, which is very far from physiological values that are mostly in the kilopascal range. Stem cells however show a high sensitivity to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e8e6b9c2c1c8982ca2d3fb2b5b1410a
https://hal.archives-ouvertes.fr/hal-02396327

Espèces réactives de l’oxygène et stress oxydant

Autor: Mireille Serres, Camille Migdal

Publikováno v: médecine/sciences. 27:405-412

Le stress oxydant se definit par un desequilibre entre la production d’especes radicalaires (ou reactives) de l’oxygene (ERO) et les capacites cellulaires antioxydantes. Les ERO ont longtemps ete considerees comme des sous-produits toxiques du me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7cb25d7b9dacb6216e1b0d9cee1c6042
https://doi.org/10.1051/medsci/2011274017

Characterization of early events involved in human dendritic cell maturation induced by sensitizers: Cross talk between MAPK signalling pathways

Autor: Béatrice Le Varlet, Camille Migdal, Sandra Trompezinski, M. Tailhardat, Pascal Courtellemont, Marek Haftek, Mireille Serres

Publikováno v: Toxicology and Applied Pharmacology. 230:397-406

Dendritic cells (DCs), efficient-antigen presenting cells play an important role in initiating and regulating immune responses. DC maturation following exposure to nickel or DNCB induced an up-regulation of phenotypic markers and inflammatory cytokin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6a55e623093e1430356c7637816393
https://doi.org/10.1016/j.taap.2008.03.012

[Reactive oxygen species and oxidative stress]

Autor: Camille, Migdal, Mireille, Serres

Publikováno v: Medecine sciences : M/S. 27(4)

Oxidative stress is defined as an imbalance between the production of reactive oxygen species (ROS) and the antioxidant capacity of the cell. For long, ROS have been considered as harmful by-products of the normal aerobic metabolism process of the mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b1083ca95c3f53f15186c9a5e38eef79
https://pubmed.ncbi.nlm.nih.gov/21524406