Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Camilla Volponi"'
Dendritic cell-targeted therapy expands CD8 T cell responses to bona-fide neoantigens in lung tumors
Autor:
Lucía López, Luciano Gastón Morosi, Federica La Terza, Pierre Bourdely, Giuseppe Rospo, Roberto Amadio, Giulia Maria Piperno, Valentina Russo, Camilla Volponi, Simone Vodret, Sonal Joshi, Francesca Giannese, Dejan Lazarevic, Giovanni Germano, Patrizia Stoitzner, Alberto Bardelli, Marc Dalod, Luigia Pace, Nicoletta Caronni, Pierre Guermonprez, Federica Benvenuti
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Cross-presentation by type 1 DCs (cDC1) is critical to induce and sustain antitumoral CD8 T cell responses to model antigens, in various tumor settings. However, the impact of cross-presenting cDC1 and the potential of DC-based therapies in
Externí odkaz:
https://doaj.org/article/f7c6a9ff87e544acbdd02715c577e12b
Autor:
Aurora Gazzillo, Camilla Volponi, Cristiana Soldani, Michela Anna Polidoro, Barbara Franceschini, Ana Lleo, Eduardo Bonavita, Matteo Donadon
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 26 (2023)
Liver cancer represents the fourth leading cause of cancer-associated death worldwide. The heterogeneity of its tumor microenvironment (TME) is a major contributing factor of metastasis, relapse, and drug resistance. Regrettably, late diagnosis makes
Externí odkaz:
https://doaj.org/article/96048340d86a4c5f9e56cebe65104a6f
Autor:
Lucia Lopez-Rodriguez, Pierre Bourdely, Federica La Terza, Giuseppe Rospo, Luciano Morosi, Roberto Amadio, Giulia Maria Piperno, Camilla Volponi, Simone Vodret, Sonal Joshi, Francesca Giannese, Dejan Lazarevic, Giovanni Germano, Patrizia Stoitzner, Alberto Bardelli, Marc Dalod, Nicoletta Caronni, Pierre Guermonprez, Federica Benvenuti
The efficacy of immune checkpoint blockade (ICB) in NSCLC depends on the tumor mutational burden (TMB). However, a fraction of patients with high TMB and predicted immunogenic neoantigens (neoAgs) do not respond. Here we show that in a model of highl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b69461aa9cfa096a596e894578f8ec5
https://doi.org/10.21203/rs.3.rs-2752957/v1
https://doi.org/10.21203/rs.3.rs-2752957/v1
Publikováno v:
Cancers. 14:6151
HCC, the most prevalent form of primary liver cancer, is prototypically an inflammation-driven cancer developing after years of inflammatory insults. Consequently, the hepatic microenvironment is a site of complex immunological activities. Moreover,