Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Camilla T, Ambivero"'
Autor:
Lucia Cilenti, Jacopo Di Gregorio, Rohit Mahar, Fei Liu, Camilla T. Ambivero, Muthu Periasamy, Matthew E. Merritt, Antonis S. Zervos
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Obesity is a growing epidemic affecting millions of people worldwide and a major risk factor for a multitude of chronic diseases and premature mortality. Accumulating evidence suggests that mitochondria have a profound role in diet-induced obesity an
Externí odkaz:
https://doaj.org/article/4e9129dc645344a9b0a8a2258082e805
Autor:
Lucia Cilenti, Rohit Mahar, Jacopo Di Gregorio, Camilla T. Ambivero, Matthew E. Merritt, Antonis S. Zervos
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
MUL1 is a multifunctional E3 ubiquitin ligase that is involved in various pathophysiological processes including apoptosis, mitophagy, mitochondrial dynamics, and innate immune response. We uncovered a new function for MUL1 in the regulation of mitoc
Externí odkaz:
https://doaj.org/article/836e49a91fde481ba036d80a3b8bea90
Autor:
Jacopo, Di Gregorio, Lucia, Cilenti, Camilla T, Ambivero, Thomas, Andl, Ronglih, Liao, Antonis S, Zervos
Publikováno v:
Biochim Biophys Acta Mol Cell Res
UBXN7 is a cofactor protein that provides a scaffold for both CRL3(KEAP1) and CRL2(VHL) ubiquitin ligase complexes involved in the regulation of the NRF2 and HIF-1α protein levels respectively. NRF2 and HIF-1α are surveillance transcription factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9e3567c7fa4cc40ff464bbe29a98ff5
https://pubmed.ncbi.nlm.nih.gov/33444648
https://pubmed.ncbi.nlm.nih.gov/33444648
Autor:
Thomas Andl, Ronglih Liao, Jacopo Di Gregorio, Lucia Cilenti, Antonis S. Zervos, Camilla T. Ambivero
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
MUL1 is a multifunctional E3 ubiquitin ligase anchored in the outer mitochondrial membrane with its RING finger domain facing the cytoplasm. MUL1 participates in various biological pathways involved in apoptosis, mitochondrial dynamics, and innate im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d7a61261388061ded362b512880234
https://doi.org/10.1038/s41598-020-58484-8
https://doi.org/10.1038/s41598-020-58484-8
Autor:
Thomas Andl, Antonis S. Zervos, Lucia Cilenti, Jacopo Di Gregorio, Ronglih Liao, Camilla T. Ambivero
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1868:118963
UBXN7 is a cofactor protein that provides a scaffold for both CRL3KEAP1 and CRL2VHL ubiquitin ligase complexes involved in the regulation of the NRF2 and HIF-1α protein levels respectively. NRF2 and HIF-1α are surveillance transcription factors tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::731e03ba4711ee7e10846fe2c89f26cb
https://doi.org/10.1016/j.bbamcr.2021.118963
https://doi.org/10.1016/j.bbamcr.2021.118963
Publikováno v:
Cellular Signalling. 26:2921-2929
Mulan is an E3 ubiquitin ligase embedded in the outer mitochondrial membrane (OMM) with its RING finger facing the cytoplasm and a large domain located in the intermembrane space (IMS). Mulan is known to have an important role in cell growth, cell de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44cd9f2f98f3caa4fae7e7fe311e2b2f
https://doi.org/10.1016/j.cellsig.2014.09.004
https://doi.org/10.1016/j.cellsig.2014.09.004
Autor:
Nathan Ward, Antonis S. Zervos, Emad S. Alnemri, Lucia Cilenti, Doris Germain, Camilla T. Ambivero
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1843:1295-1307
Omi/HtrA2 is a nuclear encoded mitochondrial serine protease with dual and opposite functions that depend entirely on its subcellular localization. During apoptosis, Omi/HtrA2 is released into the cytoplasm where it participates in cell death. While
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b3fe5d8693231f818f9be233b014fd
https://doi.org/10.1016/j.bbamcr.2014.03.027
https://doi.org/10.1016/j.bbamcr.2014.03.027
Autor:
Lucia Cilenti, Meenakshi P. Balakrishnan, Martin Sterlicchi, Antonis S. Zervos, Federica del Monte, Camilla T. Ambivero, Xiao-Liang Wang, Xin L. Ma
Publikováno v:
Journal of Molecular and Cellular Cardiology. 50:652-661
Abro1 (also known as KIAA0157) is a scaffold protein that recruits polypeptides to assemble the BRISC (BRCC36-containing isopeptidase complex) deubiquitinating (DUB) enzyme. The four subunits of BRISC enzyme include Abro1, NBA1, BRE, and BRCC36 prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce93002b161171581610efcd0620ba1
https://doi.org/10.1016/j.yjmcc.2010.12.015
https://doi.org/10.1016/j.yjmcc.2010.12.015
Autor:
Xiaoman Shawn Li, Lucia Cilenti, James Turkson, Yamafumi Goto, Camilla T. Ambivero, Meenakshi P. Balakrishnan, Minoru Takata, Antonis S. Zervos
Publikováno v:
Biochemical and Biophysical Research Communications. 404:195-200
THAP5 was originally isolated as a specific interactor and substrate of the mitochondrial pro-apoptotic Omi/HtrA2 protease. It is a human zinc finger protein characterized by a restricted pattern of expression and the lack of orthologs in mouse and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae2c6c7617ac44769ee8f6577a2e571
https://doi.org/10.1016/j.bbrc.2010.11.092
https://doi.org/10.1016/j.bbrc.2010.11.092
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. (12):2149-2156
Abro1 (Abraxas brother 1), also known as KIAA0157, is a scaffold protein that recruits various polypeptides to assemble the BRISC (BRCC36 isopeptide) deubiquitinating enzyme (DUB) complex. The BRISC enzyme has a Lys63-linked deubiquitinating activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a40c438319ec94c4e4b3e136773affd