Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Camilla Scarpellini"'
Autor:
Camilla Scarpellini, Sophie Valembois, Kenneth Goossens, Mike Vadi, Caroline Lanthier, Greta Klejborowska, Pieter Van Der Veken, Hans De Winter, Mathieu J. M. Bertrand, Koen Augustyns
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
Receptor-Interacting serine/threonine-Protein Kinase 1 (RIPK1) emerged as an important driver of inflammation and, consequently, inflammatory pathologies. The enzymatic activity of RIPK1 is known to indirectly promote inflammation by triggering cell
Externí odkaz:
https://doaj.org/article/0f93ee492f8849b39af739d171b0590b
Autor:
Donatello Laera, Camilla Scarpellini, Simona Tavarini, Barbara Baudner, Agnese Marcelli, Carlo Pergola, Malte Meppen, Derek T. O’Hagan
Publikováno v:
Vaccines, Vol 11, Iss 1, p 155 (2023)
Although aluminium-based vaccines have been used for almost over a century, their mechanism of action remains unclear. It is established that antigen adsorption to the adjuvant facilitates delivery of the antigen to immune cells at the injection site
Externí odkaz:
https://doaj.org/article/bde4b3d88f134f58a8bbf43e489a53f6
Autor:
Anusha Balla, Bao Tran, Annika Valtari, Philipp Steven, Camilla Scarpellini, Koen Augustyns, Arto Urtti, Kati-Sisko Vellonen, Marika Ruponen
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 118 (2022)
Corneal wound, associated with pain, impaired vision, and even blindness, is the most common ocular injury. In this study, we investigated the effect of a novel ferroptosis inhibitor, UAMC-3203 (10 nM–50 µM), in corneal epithelial wound healing in
Externí odkaz:
https://doaj.org/article/d1136f4a281c4e77b6f05239a3ddcb2a
Autor:
Francesco Ansideri, Joana T. Macedo, Michael Eitel, Ahmed El-Gokha, Dhafer S. Zinad, Camilla Scarpellini, Mark Kudolo, Dieter Schollmeyer, Frank M. Boeckler, Bärbel S. Blaum, Stefan A. Laufer, Pierre Koch
Publikováno v:
ACS Omega, Vol 3, Iss 7, Pp 7809-7831 (2018)
Externí odkaz:
https://doaj.org/article/d337085c21624f4fbd7965216a3191ad
Autor:
Ruponen, Anusha Balla, Bao Tran, Annika Valtari, Philipp Steven, Camilla Scarpellini, Koen Augustyns, Arto Urtti, Kati-Sisko Vellonen, Marika
Publikováno v:
Pharmaceutics; Volume 15; Issue 1; Pages: 118
Corneal wound, associated with pain, impaired vision, and even blindness, is the most common ocular injury. In this study, we investigated the effect of a novel ferroptosis inhibitor, UAMC-3203 (10 nM–50 µM), in corneal epithelial wound healing in
Publikováno v:
International journal of molecular sciences
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Dry eye disease (DED) is a multifactorial disorder that leads to ocular discomfort, visual disturbance, and tear film instability. DED is accompanied by an increase in tear osmolarity and ocular surface inflammation. The diagnosis and treatment of DE
Autor:
Mark Kudolo, Ahmed El-Gokha, Joana T. Macedo, Stefan Laufer, Pierre Koch, Baerbel S. Blaum, Francesco Ansideri, Dieter Schollmeyer, Camilla Scarpellini, Dhafer Saber Zinad, Frank M. Boeckler, Michael Eitel
Publikováno v:
ACS Omega, Vol 3, Iss 7, Pp 7809-7831 (2018)
ACS Omega
ACS Omega
Starting from known p38α mitogen-activated protein kinase (MAPK) inhibitors, a series of inhibitors of the c-Jun N-terminal kinase (JNK) 3 was obtained. Altering the substitution pattern of the pyridinylimidazole scaffold proved to be effective in s