Výsledky vyhledávání - "Camilla Reali"

B cell rich meningeal inflammation associates with increased spinal cord pathology in multiple sclerosis

Autor: Roberta Magliozzi, Richard Reynolds, Camilla Reali, Richard Nicholas, Federico Roncaroli, Owain W. Howell

Publikováno v: Reali, C, Magliozzi, R, Roncaroli, F, Nicholas, R, Howell, O W & Reynolds, R 2020, ' B cell rich meningeal inflammation associates with increased spinal cord pathology in multiple sclerosis ', Brain Pathology . https://doi.org/10.1111/bpa.12841
Brain Pathology

Increased inflammation in the cerebral meninges is associated with extensive subpial cortical grey matter pathology in the forebrain and a more severe disease course in a substantial proportion of secondary progressive multiple sclerosis (SPMS) cases

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80335bce4b61e1915d57b2251f35cbc
https://doi.org/10.1111/bpa.12841

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RORγt Expression and Lymphoid Neogenesis in the Brain of Patients with Secondary Progressive Multiple Sclerosis

Autor: Barbara Rosicarelli, Caterina Veroni, Francesca Aloisi, Barbara Serafini, Camilla Reali, Ling Zhou

Publikováno v: Journal of Neuropathology & Experimental Neurology. 75:877-888

Ectopic B-cell follicle-like structures (ELS) are found in the meninges of patients with secondary progressive multiple sclerosis (SPMS). Because cells expressing the transcriptional regulator retinoic acid receptor-related orphan receptor-γt (RORγ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a43bd5ff237b8931a59bbc4390fadf9
https://doi.org/10.1093/jnen/nlw063

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S100B modulates growth factors and costimulatory molecules expression in cultured human astrocytes

Autor: Stefano Cabras, Valeria Sogos, Camilla Reali, Rita Pillai, Francesca Saba, Fabrizio Michetti

Publikováno v: Journal of Neuroimmunology. 243:95-99

S100B is a Ca(2+)-binding protein expressed in the nervous system. Increased levels of S100B in the extracellular space have been detected in several neurological disorders. We investigated the response of human astrocytes to micromolar chronic conce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00638c4912263e8b5e71b8bb99298903
https://doi.org/10.1016/j.jneuroim.2011.11.011

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Human astrocytes can be induced to differentiate into cells with neuronal phenotype

Autor: Luca Murru, Stefano Cabras, Rita Pillai, F. Scintu, Laura Scorciapino, Mario Carta, Giovanni Biggio, Valeria Sogos, Camilla Reali

Publikováno v: Experimental Cell Research. 312:2336-2346

Several recent studies have proposed that astrocytes may contribute to neurogenesis, not only as a source of trophic substances regulating it, but also as stem cells themselves. In order to better understand these mechanisms, primary astrocyte cultur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc22750acdb73fdbcf9a444e6a3980d
https://doi.org/10.1016/j.yexcr.2006.03.031

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Developmentally regulated expression and localization of dystrophin and utrophin in the human fetal brain

Autor: Valeria Sogos, Monica Curto, F. Gremo, Camilla Reali

Publikováno v: Mechanisms of Ageing and Development. 123:455-462

Expression of dystrophin and the dystrophin-related protein utrophin has been studied in the human fetal brain both in vivo and in vitro. Results showed that both these proteins were developmentally regulated, even if their expression followed a diff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77b6a47fd945201844efbe24cd7a3e7
https://doi.org/10.1016/s0047-6374(01)00360-8

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Antidepressant imipramine induces human astrocytes to differentiate into cells with neuronal phenotype

Autor: Valeria Sogos, Giovanni Biggio, Camilla Reali, Annarita Sirigu, Stefano Cabras, Francesca Saba, Maria Laura Scorciapino, Giuseppe Talani

Publikováno v: The international journal of neuropsychopharmacology. 13(5)

Several recent studies have expanded our conception of the role of astrocytes in neurogenesis, proposing that these cells may contribute to this phenomenon not only as a source of trophic substances, but also as stem cells themselves. We recently obs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a1cd3d5e31640c678416605bc204b5
https://pubmed.ncbi.nlm.nih.gov/20356437

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Attenuation of proliferation in oligodendrocyte precursor cells by activated microglia

Autor: Samantha Holland, Camilla Reali, Deanna L. Taylor, Adele L. Norman, Djordje Gveric, Huseyin Mehmet, Grisha Pirianov, Lara T. Diemel, Davy Yeung, Colm J. McGinnity

Publikováno v: Journal of Neuroscience Research.

Activated microglia can influence the survival of neural cells through the release of cytotoxic factors. Here, we investigated the interaction between Toll-like receptor 4 (TLR4)-activated microglia and oligodendrocytes or their precursor cells (OPC)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a69356d573921d2fe632988b7fa58df3
https://doi.org/10.1002/jnr.22335

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Differentiation of human bone marrow stem cells into cells with a neural phenotype: diverse effects of two specific treatments

Autor: Maria Adele Sanna, F. Scintu, Manuela Badiali, F Argiolu, Rita Pillai, Maria Serafina Ristaldi, Valeria Sogos, Camilla Reali

Publikováno v: BMC Neuroscience, Vol 7, Iss 1, p 14 (2006)
BMC Neuroscience

Background It has recently been demonstrated that the fate of adult cells is not restricted to their tissues of origin. In particular, it has been shown that bone marrow stem cells can give rise to cells of different tissues, including neural cells,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c259ec0c045c45b86458f78766dd82
http://www.biomedcentral.com/1471-2202/7/14

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Differentiation of human adult CD34+ stem cells into cells with a neural phenotype: role of astrocytes

Autor: F Argiolu, Maria Adele Sanna, F. Scintu, Stefano Cabras, Camilla Reali, Rita Pillai, Manuela Badiali, Valeria Sogos, Maria Serafina Ristaldi

Publikováno v: Experimental neurology. 197(2)

It has recently been reported that adult hematopoietic stem cells can differentiate into neural cells, opening new frontiers in therapy for neurodegenerative diseases. In this study, adult human hematopoietic stem cells (HSCs) were isolated via magne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51fe3ef67b14419d115bbb2ef7ad2980
https://pubmed.ncbi.nlm.nih.gov/16298364

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S100b counteracts effects of the neurotoxicant trimethyltin on astrocytes and microglia

Autor: Valeria Sogos, Rosario Donato, Fabrizio Michetti, Camilla Reali, Rita Pillai, F. Scintu

Central nervous system degenerative diseases are often characterized by an early, strong reaction of astrocytes and microglia. Both these cell types can play a double role, protecting neurons against degeneration through the synthesis and secretion o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a185c83e2c2852dbabe9a9439080cdd6
http://hdl.handle.net/10807/6015

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