Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Camilla Myrup Holst"'
Autor:
Ines Sanchez-Roman, Beatriz Ferrando, Camilla Myrup Holst, Jonas Mengel-From, Signe Hoei Rasmussen, Mikael Thinggaard, Vilhelm A. Bohr, Kaare Christensen, Tinna Stevnsner
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 909 (2024)
Mitochondrial dysfunction and genomic instability are key hallmarks of aging. The aim of this study was to evaluate whether maintenance of physical capacities at very old age is associated with key hallmarks of aging. To investigate this, we measured
Externí odkaz:
https://doaj.org/article/3ba9bd023012494abc164fa3afd28d14
Autor:
Camilla Myrup Holst, Nanna Brøndum Andersen, Vibeke Thinggaard, Mine Tilken, Sofie Lautrup, Cinzia Tesauro, Tinna Stevnsner
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 355 (2023)
The DNA glycosylase NEIL2 plays a central role in maintaining genome integrity, in particular during oxidative stress, by recognizing oxidized base lesions and initiating repair of these via the base excision repair (BER) pathway. Post-translational
Externí odkaz:
https://doaj.org/article/79bd7051cfde425985f634d43819c5e5
Autor:
Signe Holm, Rikke Møller Larsen, Camilla Myrup Holst, Mads Peter Heide-Jørgensen, John Fleng Steffensen, Tinna Stevnsner, Knud Larsen
Publikováno v:
Holm, S, Larsen, R M, Holst, C M, Heide-Jørgensen, M P, Steffensen, J F, Stevnsner, T & Larsen, K 2023, ' Bowhead NEIL1 : molecular cloning, characterization, and enzymatic properties ', Biochimie, vol. 206, pp. 136-149 . https://doi.org/10.1016/j.biochi.2022.10.014
Holm, S, Larsen, R M, Holst, C M, Heide-Jørgensen, M P, Steffensen, J F, Stevnsner, T & Larsen, K 2022, ' Bowhead NEIL1 : molecular cloning, characterization, and enzymatic properties ', Biochimie, vol. 206, pp. 136-149 . https://doi.org/10.1016/j.biochi.2022.10.014
Holm, S, Larsen, R M, Holst, C M, Heide-Jørgensen, M P, Steffensen, J F, Stevnsner, T & Larsen, K 2022, ' Bowhead NEIL1 : molecular cloning, characterization, and enzymatic properties ', Biochimie, vol. 206, pp. 136-149 . https://doi.org/10.1016/j.biochi.2022.10.014
Nei Like DNA Glycosylase 1 (NEIL1) is a DNA glycosylase, which specifically processes oxidative DNA damage by initiating base excision repair. NEIL1 recognizes and removes bases, primarily oxidized pyrimidines, which have been damaged by endogenous o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e817d8392273fa72252127077b8387
https://curis.ku.dk/portal/da/publications/bowhead-neil1(717280de-ed0b-4ddd-b671-299d350c529d).html
https://curis.ku.dk/portal/da/publications/bowhead-neil1(717280de-ed0b-4ddd-b671-299d350c529d).html
Autor:
Ines Sanchez-Roman, Beatriz Ferrando, Camilla Myrup Holst, Jonas Mengel-From, Signe Høi Rasmussen, Mikael Thinggaard, Vilhelm A. Bohr, Kaare Christensen, Tinna Stevnsner
Publikováno v:
GeroScience
Sanchez-Roman, I, Ferrando, B, Holst, C M, Mengel-From, J, Rasmussen, S H, Thinggaard, M, Bohr, V A, Christensen, K & Stevnsner, T 2022, ' Molecular markers of DNA repair and brain metabolism correlate with cognition in centenarians ', GeroScience, vol. 44, no. 1, pp. 103-125 . https://doi.org/10.1007/s11357-021-00502-2
Sanchez-Roman, I, Ferrando, B, Holst, C M, Mengel-From, J, Rasmussen, S H, Thinggaard, M, Bohr, V A, Christensen, K & Stevnsner, T 2022, ' Molecular markers of DNA repair and brain metabolism correlate with cognition in centenarians ', GeroScience, vol. 44, no. 1, pp. 103-125 . https://doi.org/10.1007/s11357-021-00502-2
Oxidative stress is an important factor in age-associated neurodegeneration. Accordingly, mitochondrial dysfunction and genomic instability have been considered as key hallmarks of aging and have important roles in age-associated cognitive decline an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8c481987090a5391a33be38b13830b
https://europepmc.org/articles/PMC8810979/
https://europepmc.org/articles/PMC8810979/