Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Camilla Josephine Larsen"'
Autor:
Christina Nielsen, Iris Perez-Gassol, Anna Karlsson, Michael Gabl, Camilla Josephine Larsen, Huamei Forsman, Claes Dahlgren, Malene Winther, Ji Ming Wang, Sarah Line Skovbakke, André Holdfeldt, Henrik Franzyk
Publikováno v:
Holdfeldt, A, Skovbakke, S L, Winther, M, Gabl, M, Nielsen, C, Perez-Gassol, I, Larsen, C J, Wang, J M, Karlsson, A, Dahlgren, C, Forsman, H & Franzyk, H 2016, ' The Lipidated Peptidomimetic Lau-((S)-Aoc)-(Lys-βNphe)6-NH2Is a Novel Formyl Peptide Receptor 2 Agonist That Activates Both Human and Mouse Neutrophil NADPH Oxidase ', Journal of Biological Chemistry . https://doi.org/10.1074/jbc.m116.736850
Neutrophils expressing formyl peptide receptor 2 (FPR2) play key roles in host defense, immune regulation, and resolution of inflammation. Consequently, the search for FPR2-specific modulators has attracted much attention due to its therapeutic poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99dc119f85aaa45ef121e1c2a6ec4143
https://doi.org/10.1074/jbc.m116.736850
https://doi.org/10.1074/jbc.m116.736850
Autor:
Henrik Franzyk, Huamei Forsman, Claes Dahlgren, Peter M. H. Heegaard, Sarah Line Skovbakke, Camilla Josephine Larsen
Publikováno v:
Skovbakke, S L, Heegaard, P M H, Larsen, C J, Franzyk, H, Forsman, H & Dahlgren, C 2015, ' The Proteolytically Stable Peptidomimetic Pam-(Lys-ßNSpe) 6-NH 2 Selectively Inhibits Human Neutrophil Activation via Formyl Peptide Receptor 2 ', Biochemical Pharmacology, vol. 93, no. 2, pp. 182–195 . https://doi.org/10.1016/j.bcp.2014.11.004
Immunomodulatory host defense peptides (HDPs) are considered to be lead compounds for novel anti-sepsis and anti-inflammatory agents. However, development of drugs based on HDPs has been hampered by problems with toxicity and low bioavailability due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4977ead7d2870b34c54e691e4140e6ae
https://doi.org/10.1016/j.bcp.2014.11.004
https://doi.org/10.1016/j.bcp.2014.11.004
Autor:
Niloofar Yavari, Peter E. Nielsen, Henrik Franzyk, Camilla Josephine Larsen, Anna Mette Hansen, Gitte Bonke
Publikováno v:
Bioconjugate chemistry. 27(4)
Antisense peptide nucleic acid (PNA) oligomers constitute a novel class of potential antibiotics that inhibit bacterial growth via specific knockdown of essential gene expression. However, discovery of efficient, nontoxic delivery vehicles for such P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7b54f5c72482c47442e97e396948ff
https://pubmed.ncbi.nlm.nih.gov/26938833
https://pubmed.ncbi.nlm.nih.gov/26938833
Publikováno v:
FEMS yeast research. 15(3)
Due to increased occurrence of infections and food spoilage caused by yeast, there is an unmet need for new antifungal agents. The arginine-β-(2,5,7-tri-tert-butylindol-3-yl) alanine-arginine (R-Tbt-R) motif was previously proved useful in the desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c2b1a06b2ea02fc4207a8fdc97c8ea5
https://pubmed.ncbi.nlm.nih.gov/25761917
https://pubmed.ncbi.nlm.nih.gov/25761917
Autor:
Henrik Franzyk, Sarah Line Skovbakke, Camilla Josephine Larsen, Peter M. H. Heegaard, Lise Moesby
Publikováno v:
Journal of medicinal chemistry. 58(2)
In this study, we investigated, optimized, and characterized a novel subclass of host defense peptide (HDP) mimics based on α-peptide/β-peptoid hybrid oligomers with an alternating cationic/hydrophobic design with respect to their ability to modula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7272621ab34964b26d386d1de04eb4d1
https://pubmed.ncbi.nlm.nih.gov/25489798
https://pubmed.ncbi.nlm.nih.gov/25489798