Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Camilla Ingeson-Carlsson"'
Publikováno v:
Molecular and Cellular Endocrinology. 381:241-254
Loss of sodium-iodide symporter (NIS) expression in thyroid tumour cells primarily caused by constitutive MAPK pathway activation is often refractory to small molecule MAPK inhibitors. Suggested mechanisms are rebound MAPK signalling and activation o
Autor:
Therese Carlsson, Jan-Olof Karlsson, Ola Hammarsten, Jakob Himmelman, Per Postgård, Nirmal Kapoor, Mikael Nilsson, Madeleine Nordén Lyckesvärd, Camilla Ingeson-Carlsson, Eva Forssell-Aronsson
Publikováno v:
Experimental cell research. 344(1)
Radiotherapy of thyroid cancer with I-131 is abrogated by inherent loss of radioiodine uptake due to loss of sodium iodide symporter (NIS) expression in poorly differentiated tumor cells. It is also known that ionizing radiation per se down-regulates
Publikováno v:
Experimental cell research. 338(2)
Tumor microenvironment influences targeted drug therapy. In this study we compared drug responses to RAF and MEK inhibitors on tumor cell migration in 2D and 3D culture of BRAF(V600E) mutant cell lines derived from human papillary (BCPAP) and anaplas
Autor:
Daniela Padula, Shawn Liang, Therese Carlsson, Jessica Örnros, Daniel L. Altschuler, Mikael Nilsson, Heiko Lickert, Ellen Johansson, Henrik Fagman, Svante Jansson, Luca Parrillo, Louise Andersson, Pietro Zoppoli, Jakob Dahlberg, Camilla Ingeson-Carlsson, Guillermo Barila
Publikováno v:
Development.
Current understanding infers a neural crest origin of thyroid C cells, the major source of calcitonin in mammals and ancestors to neuroendocrine thyroid tumors. The concept is primarily based on investigations in quail-chick chimeras involving fate-m
Publikováno v:
Experimental cell research. 326(2)
Normal thyrocytes grown as reconstituted follicles in collagen gel were evaluated for drug effects of small molecule kinase inhibitors on growth factor-induced cell migration in a 3D context. MEK inhibition by U0126 only partially antagonized EGF/ser