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pro vyhledávání: '"Camilla H.F. Hansen"'
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes
Autor:
Matthew C. Funsten, Leonid A. Yurkovetskiy, Andrey Kuznetsov, Derek Reiman, Camilla H.F. Hansen, Katharine I. Senter, Jean Lee, Jeremy Ratiu, Shiva Dahal-Koirala, Dionysios A. Antonopoulos, Gary M. Dunny, Ludvig M. Sollid, David Serreze, Aly A. Khan, Alexander V. Chervonsky
Publikováno v:
Cell Host & Microbe. 31:213-227.e9
Diet and commensals can affect the development of autoimmune diseases like type 1 diabetes (T1D). However, whether dietary interventions are microbe-mediated was unclear. We found that a diet based on hydrolyzed casein (HC) as a protein source protec
Autor:
Camilla H.F. Hansen, Christian S. Larsen, Line F. Zachariassen, Caroline M.J. Mentzel, Ann Laigaard, Lukasz Krych, Dennis S. Nielsen, Alex Gobbi, Martin Haupt-Jorgensen, Karsten Buschard, Axel K. Hansen
Publikováno v:
Journal of autoimmunity. 127
Experimental and clinical data suggest that a gluten-free diet attenuates the development of type 1 diabetes. A gluten-free diet changes the gut microbiota composition, and such microbial changes are expected to reduce the autoimmune responses. Howev