Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Camilla Albano"'
Targeting Peptidylarginine Deiminase 3 to Efficiently Suppress Herpes Simplex Virus Type 2 Infection
Autor:
Selina Pasquero, Francesca Gugliesi, Matteo Biolatti, Camilla Albano, Greta Bajetto, Linda Trifirò, Stefano Raviola, Valentina Dell’Oste, Marco De Andrea
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8709 (2024)
Protein expression is regulated through multiple mechanisms, including post-translational modifications (PTMs), which can alter protein structure, stability, localization, and function. Among these, citrullination stands out due to its ability to con
Externí odkaz:
https://doaj.org/article/95de3ad26ed34b65a9a20306289c3210
Autor:
Camilla Albano, Matteo Biolatti, Jasenka Mazibrada, Selina Pasquero, Francesca Gugliesi, Irene Lo Cigno, Federica Calati, Greta Bajetto, Giuseppe Riva, Gloria Griffante, Santo Landolfo, Marisa Gariglio, Marco De Andrea, Valentina Dell’Oste
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Citrullination is an emerging post-translational modification catalyzed by peptidyl-arginine deiminases (PADs) that convert peptidyl-arginine into peptidyl-citrulline. In humans, the PAD family consists of five isozymes (PADs 1-4, 6) involved in mult
Externí odkaz:
https://doaj.org/article/42f075546eb64640a5dc70ecfc043410
Autor:
Selina Pasquero, Francesca Gugliesi, Matteo Biolatti, Valentina Dell'Oste, Camilla Albano, Greta Bajetto, Gloria Griffante, Linda Trifirò, Bianca Brugo, Stefano Raviola, Davide Lacarbonara, Qiao Yang, Sen Sudeshna, Leonard Barasa, Hafeez Haniff, Paul R Thompson, Santo Landolfo, Marco De Andrea
Publikováno v:
PLoS Pathogens, Vol 19, Iss 12, p e1011849 (2023)
Herpes simplex virus 1 (HSV-1) is a neurotropic virus that remains latent in neuronal cell bodies but reactivates throughout an individual's life, causing severe adverse reactions, such as herpes simplex encephalitis (HSE). Recently, it has also been
Externí odkaz:
https://doaj.org/article/9ab133fae77743a9b39e0c3aef5aae35
Autor:
Greta Bajetto, Davide Arnodo, Matteo Biolatti, Linda Trifirò, Camilla Albano, Selina Pasquero, Francesca Gugliesi, Eva Campo, Francesca Spyrakis, Cristina Prandi, Marco De Andrea, Valentina Dell’Oste, Ivan Visentin, Marco Blangetti
Publikováno v:
Microorganisms, Vol 12, Iss 2, p 373 (2024)
The rise of drug resistance to antivirals poses a significant global concern for public health; therefore, there is a pressing need to identify novel compounds that can effectively counteract strains resistant to current antiviral treatments. In ligh
Externí odkaz:
https://doaj.org/article/2057bb3f3c7d4327b804520bc62a899b
Autor:
Gloria Griffante, Weronika Hewelt-Belka, Camilla Albano, Francesca Gugliesi, Selina Pasquero, Sergio Fernando Castillo Pacheco, Greta Bajetto, Paolo Ettore Porporato, Erica Mina, Marta Vallino, Christian Krapp, Martin Roelsgaard Jakobsen, John Purdy, Jens von Einem, Santo Landolfo, Valentina Dell’Oste, Matteo Biolatti
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Cellular lipid metabolism plays a pivotal role in human cytomegalovirus (HCMV) infection, as increased lipogenesis in HCMV-infected cells favors the envelopment of newly synthesized viral particles. As all cells are equipped with restriction
Externí odkaz:
https://doaj.org/article/b40fe9f446da4f5a9789a39792830e92
Autor:
Francesca Gugliesi, Selina Pasquero, Gloria Griffante, Sara Scutera, Camilla Albano, Sergio Fernando Castillo Pacheco, Giuseppe Riva, Valentina Dell’Oste, Matteo Biolatti
Publikováno v:
Viruses, Vol 13, Iss 2, p 260 (2021)
Human cytomegalovirus (HCMV) is a ubiquitous double-stranded DNA virus belonging to the β-subgroup of the herpesvirus family. After the initial infection, the virus establishes latency in poorly differentiated myeloid precursors from where it can re
Externí odkaz:
https://doaj.org/article/4df964596e5449848287265bb50fdfdf
Autor:
Giuseppe Riva, Camilla Albano, Francesca Gugliesi, Selina Pasquero, Sergio Fernando Castillo Pacheco, Giancarlo Pecorari, Santo Landolfo, Matteo Biolatti, Valentina Dell’Oste
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1402 (2021)
Besides smoking and alcohol, human papillomavirus (HPV) is a factor promoting head and neck squamous cell carcinoma (HNSCC). In some human tumors, including HNSCC, a number of mutations are caused by aberrantly activated DNA-modifying enzymes, such a
Externí odkaz:
https://doaj.org/article/4d847260bb984b76880cd77d9ddedd0f
Autor:
Matteo Biolatti, Marco Blangetti, Giulia D’Arrigo, Francesca Spyrakis, Paola Cappello, Camilla Albano, Paolo Ravanini, Santo Landolfo, Marco De Andrea, Cristina Prandi, Valentina Dell’Oste
Publikováno v:
Microorganisms, Vol 8, Iss 5, p 703 (2020)
The human cytomegalovirus (HCMV) is a widespread pathogen and is associated with severe diseases in immunocompromised individuals. Moreover, HCMV infection is the most frequent cause of congenital malformation in developed countries. Although nucleos
Externí odkaz:
https://doaj.org/article/65b2b1f8dc664e24a458a738bd3cdeb2
Autor:
Francesca Gugliesi, Alessandra Coscia, Gloria Griffante, Ganna Galitska, Selina Pasquero, Camilla Albano, Matteo Biolatti
Publikováno v:
Microorganisms, Vol 8, Iss 5, p 685 (2020)
Human cytomegalovirus (HCMV), a linear double-stranded DNA betaherpesvirus belonging to the family of Herpesviridae, is characterized by widespread seroprevalence, ranging between 56% and 94%, strictly dependent on the socioeconomic background of the
Externí odkaz:
https://doaj.org/article/28eb5fe793ac4fabb17b288877d7103d
Novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2
Autor:
Selina Pasquero, Francesca Gugliesi, Gloria Griffante, Valentina Dell’Oste, Matteo Biolatti, Camilla Albano, Greta Bajetto, Serena Delbue, Lucia Signorini, Maria Dolci, Santo Landolfo, Marco De Andrea
Publikováno v:
Antiviral research. 200
The current SARS-CoV-2 pandemic, along with the likelihood that new coronavirus strains will appear in the nearby future, highlights the urgent need to develop new effective antiviral agents. In this scenario, emerging host-targeting antivirals (HTAs