Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Camilla A. Hansson"'
Autor:
Petersen, Camilla A. Hansson, Alikhani, Nyosha, Behbahani, Homira, Wiehager, Birgitta, Pavlov, Pavel F., Alafuzoff, Irina, Leinonen, Ville, Ito, Akira, Winblad, Bengt, Glaser, Elzbieta, Ankarcrona, Maria
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2008 Sep 01. 105(35), 13145-13150.
Externí odkaz:
https://www.jstor.org/stable/25464005
γ-secretase complexes containing caspase-cleaved presenilin-1 increase intracellular Aβ42/Aβ40 ratio
Autor:
Lars O. Tjernberg, Louise Hedskog, Helena Karlström, Anne-Lie Svensson, Hedvig Welander, Maria Ankarcrona, Camilla A. Hansson Petersen
Publikováno v:
Journal of Cellular and Molecular Medicine
Markers for caspase activation and apoptosis have been shown in brains of Alzheimer's disease (AD) patients and AD-mouse models. In neurons, caspase activation is associated with elevated amyloid β-peptide (Aβ) production. Caspases cleave numerous
Publikováno v:
Journal of Cellular and Molecular Medicine
Accumulating evidence suggest that alterations in energy metabolism are among the earliest events that occur in the Alzheimer disease (AD) affected brain. Energy consumption is drastically decreased in the AD-affected regions of cerebral cortex and h
Autor:
Ville Leinonen, Birgitta Wiehager, Bengt Winblad, Akira Ito, Nyosha Alikhani, Maria Ankarcrona, Pavel F. Pavlov, Camilla A. Hansson Petersen, Irina Alafuzoff, Homira Behbahani, Elzbieta Glaser
Publikováno v:
Proceedings of the National Academy of Sciences. 105:13145-13150
The amyloid β-peptide (Aβ) has been suggested to exert its toxicity intracellularly. Mitochondrial functions can be negatively affected by Aβ and accumulation of Aβ has been detected in mitochondria. Because Aβ is not likely to be produced local
Autor:
Angel Cedazo-Minguez, Camilla A. Hansson, Bengt Winblad, Bogdan Ovidiu Popescu, Maria Ankarcrona, Hanna Laudon, Laurentiu M. Popescu
Publikováno v:
Journal of Neurochemistry. 97:356-364
gamma-Secretase is a key enzyme involved in the processing of the beta-amyloid precursor protein into amyloid beta-peptides (Abeta). Abeta accumulates and forms plaques in Alzheimer's disease (AD) brains. A progressive neurodegeneration and cognitive
Publikováno v:
Journal of Alzheimer's disease : JAD. 21(2)
Dimebon, a drug currently being evaluated in multiple Phase III Alzheimer's disease trials, has previously been shown to have effects on isolated mitochondria at muM concentrations. Here the effects of nM concentrations of Dimebon on mitochondrial fu
P1‐471: Alzheimer‐associated Aβ peptides are imported into mitochondria via the Tom import machinery
Autor:
Maria Ankarcrona, Camilla A. Hansson, Homira Behbahani, Birgitta Wiehager, Nyosha Alikhani, Pavel F. Pavlov, Bengt Winblad, Elzbieta Glaser
Publikováno v:
Alzheimer's & Dementia. 4
Publikováno v:
Alzheimer's & Dementia. 4
Autor:
Camilla A, Hansson, Bogdan O, Popescu, Hanna, Laudon, Angel, Cedazo-Minguez, Laurentiu M, Popescu, Bengt, Winblad, Maria, Ankarcrona
Publikováno v:
Journal of neurochemistry. 97(2)
gamma-Secretase is a key enzyme involved in the processing of the beta-amyloid precursor protein into amyloid beta-peptides (Abeta). Abeta accumulates and forms plaques in Alzheimer's disease (AD) brains. A progressive neurodegeneration and cognitive
Autor:
Maria Ankarcrona, Richard F. Cowburn, Camilla A. Hansson, Sharon E. Pursglove, Johan Thyberg, Akira Ito, Camilla Nilsberth, Mark R. Farmery, Susanne Frykman, Bengt Winblad, Lars O. Tjernberg
Publikováno v:
The Journal of biological chemistry. 279(49)
Mitochondria are central in the regulation of cell death. Apart from providing the cell with ATP, mitochondria also harbor several death factors that are released upon apoptotic stimuli. Alterations in mitochondrial functions, increased oxidative str