Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Camilla Foged"'
Autor:
Abishek Wadhwa, Thomas R. Bobak, Lennart Bohrmann, Reka Geczy, Sathiya Sekar, Gowtham Sathyanarayanan, Jörg P. Kutter, Henrik Franzyk, Camilla Foged, Katayoun Saatchi, Urs O. Häfeli
Publikováno v:
OpenNano, Vol 13, Iss , Pp 100180- (2023)
Nanomedicines based on nanoparticles rely both on the potency of the drug as well as the efficiency of the delivery system, for which particle size plays a crucial role. For the intracellular delivery of small interference RNA (siRNA), lipid-polymer
Externí odkaz:
https://doaj.org/article/a24eb0be3e2c4dbe91a0350992d611c3
Autor:
Suzan M Hammond, Annemieke Aartsma‐Rus, Sandra Alves, Sven E Borgos, Ronald A M Buijsen, Rob W J Collin, Giuseppina Covello, Michela A Denti, Lourdes R Desviat, Lucía Echevarría, Camilla Foged, Gisela Gaina, Alejandro Garanto, Aurelie T Goyenvalle, Magdalena Guzowska, Irina Holodnuka, David R Jones, Sabine Krause, Taavi Lehto, Marisol Montolio, Willeke Van Roon‐Mom, Virginia Arechavala‐Gomeza
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 4, Pp n/a-n/a (2021)
Abstract Nucleic acid‐based therapeutics that regulate gene expression have been developed towards clinical use at a steady pace for several decades, but in recent years the field has been accelerating. To date, there are 11 marketed products based
Externí odkaz:
https://doaj.org/article/76e52486fd764de6bb07b4e5106b079a
Autor:
You Xu, Elisa Parra-Ortiz, Feng Wan, Olga Cañadas, Begoña Garcia-Alvarez, Aneesh Thakur, Henrik Franzyk, Jesús Pérez-Gil, Martin Malmsten, Camilla Foged
Publikováno v:
Xu, Y, Parra-Ortiz, E, Wan, F, Cañadas, O, Garcia-Alvarez, B, Thakur, A, Franzyk, H, Pérez-Gil, J, Malmsten, M & Foged, C 2023, ' Insights into the mechanisms of interaction between inhalable lipid-polymer hybrid nanoparticles and pulmonary surfactant ', Journal of Colloid and Interface Science, vol. 633, pp. 511-525 . https://doi.org/10.1016/j.jcis.2022.11.059
Pulmonary delivery of small interfering RNA (siRNA) using nanoparticle-based delivery systems is promising for local treatment of respiratory diseases. We designed dry powder inhaler formulations of siRNA-loaded lipid-polymer hybrid nanoparticles (LP
Autor:
Abhijeet Lokras, Aneesh Thakur, Abishek Wadhwa, Kaushik Thanki, Henrik Franzyk, Camilla Foged
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2021)
RNA interference (RNAi) has an unprecedented potential as a therapeutic strategy for reversibly silencing the expression of any gene. Therapeutic delivery of the RNAi mediator, i.e., small interfering RNA (siRNA), can be used to address diseases char
Externí odkaz:
https://doaj.org/article/5769adcc7a7d4afe8b6c9ab66fafbf57
Autor:
Olivia Amanda Oest Müllertz, Peter Andersen, Dennis Christensen, Camilla Foged, Aneesh Thakur
Publikováno v:
Molecular Pharmaceutics. 20:953-970
Mucosal surfaces of the lungs represent a major site of entry for airborne pathogens, and pulmonary administration of vaccines is an attractive strategy to induce protective mucosal immunity in the airways. Recently, we demonstrated the potential of
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
There is an urgent need for effective countermeasures against the current emergence and accelerating expansion of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Induction of herd immunity
Externí odkaz:
https://doaj.org/article/025e29749c0e47b693415997184fa88c
Autor:
Aneesh Thakur, Fernanda Endringer Pinto, Harald Severin Hansen, Peter Andersen, Dennis Christensen, Christian Janfelt, Camilla Foged
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Understanding the in vivo fate of vaccine antigens and adjuvants and their safety is crucial for the rational design of mucosal subunit vaccines. Prime and pull vaccination using the T helper 17-inducing adjuvant CAF01 administered parenterally and m
Externí odkaz:
https://doaj.org/article/208864de0958477b8908d11a71adc163
Autor:
Anne Marit de Groot, Kaushik Thanki, Monique Gangloff, Emily Falkenberg, Xianghui Zeng, Djai C.J. van Bijnen, Willem van Eden, Henrik Franzyk, Hanne M. Nielsen, Femke Broere, Nick J. Gay, Camilla Foged, Alice J.A.M. Sijts
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 11, Iss C, Pp 159-169 (2018)
Therapeutics based on small interfering RNA (siRNA) have promising potential as antiviral and anti-inflammatory agents. To deliver siRNA across cell membranes to reach the RNAi pathway in the cytosol of target cells, non-viral nanoparticulate deliver
Externí odkaz:
https://doaj.org/article/8b2e828dc91a4199a7135eccfe8c545c
Autor:
Aneesh Thakur, Abishek Wadhwa, Abhijeet Lokras, Olivia Amanda Oest Müllertz, Dennis Christensen, Henrik Franzyk, Camilla Foged
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics.
Autor:
Sebastian Vencken, Camilla Foged, Joanne M. Ramsey, Louise Sweeney, Sally-Ann Cryan, Ronan J. MacLoughlin, Catherine M. Greene
Publikováno v:
ERJ Open Research, Vol 5, Iss 2 (2019)
Modulation of microRNAs (miRNAs), endogenous regulators of gene expression, is a promising strategy for tackling inflammatory lung diseases. In this proof-of-concept study, we tested delivery of miR-17 to bronchial epithelial cells (BECs) using nebul
Externí odkaz:
https://doaj.org/article/6e771108edc74bdaa53322887086e374