Local Inhibition of Indoleamine 2,3-Dioxygenase Mitigates Renal Fibrosis

Autor: Camilla Grønkjær Jensen, Michael Schou Jensen, Stine Julie Tingskov, Peter Olinga, Rikke Nørregaard, Henricus A. M. Mutsaers

Publikováno v: Biomedicines, Vol 9, Iss 8, p 856 (2021)

Chronic kidney disease (CKD) is a major global health concern and renal fibrosis is an integral part of the pathophysiological mechanism underlying disease progression. In CKD patients, the majority of metabolic pathways are in disarray and perturbat

Externí odkaz: https://doaj.org/article/5ea543bde1f247678b8bccba04d413ee

Local Inhibition of Indoleamine 2,3-Dioxygenase Mitigates Renal Fibrosis

Autor: Michael Schou Jensen, Rikke Nørregaard, Henricus A. M. Mutsaers, Stine Julie Tingskov, Peter Olinga, Camilla Grønkjær Jensen

Publikováno v: Biomedicines
Volume 9
Issue 8
Biomedicines, 9(8):856. MDPI AG
Biomedicines, Vol 9, Iss 856, p 856 (2021)
Jensen, C G, Jensen, M S, Tingskov, S J, Olinga, P, Nørregaard, R & Mutsaers, H A M 2021, ' Local inhibition of indoleamine 2, 3-dioxygenase mitigates renal fibrosis ', Biomedicines, vol. 9, no. 8, 856 . https://doi.org/10.3390/biomedicines9080856
Jensen, C G, Jensen, M S, Tingskov, S J H, Olinga, P, Nørregaard, R & Mutsaers, H A M 2021, ' Local Inhibition of Indoleamine 2,3-Dioxygenase Mitigates Renal Fibrosis ', Biomedicines . https://doi.org/10.3390/biomedicines9080856

Chronic kidney disease (CKD) is a major global health concern and renal fibrosis is an integral part of the pathophysiological mechanism underlying disease progression. In CKD patients, the majority of metabolic pathways are in disarray and perturbat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff094b2a8967d0d0f524445b6cb533c

Atorvastatin does not ameliorate nephrogenic diabetes insipidus induced by lithium or potassium depletion in mice

Autor: Anna Iervolino, Soham Rej, Camilla Grønkjær, Birgitte Mønster Christensen, Maria L. Thomsen, Francesco Trepiccione

Publikováno v: Markussen, M L, Jensen, C G, Iervolino, A, Rej, S, Trepiccione, F & Christensen, B M 2021, ' Atorvastatin does not ameliorate nephrogenic diabetes insipidus induced by lithium or potassium depletion in mice ', Physiological Reports, vol. 9, no. 21, e15111 . https://doi.org/10.14814/phy2.15111
Physiological Reports
Physiological Reports, Vol 9, Iss 21, Pp n/a-n/a (2021)

Acquired forms of nephrogenic diabetes insipidus (NDI) include lithium (Li)‐induced and hypokalemia‐induced NDI. Both forms are associated with AQP2 downregulation and collecting duct (CD) cellular remodeling. Statins are cholesterol‐lowering d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c42606e35cf9f3eab150393a79c29d3
https://pure.au.dk/portal/da/publications/atorvastatin-does-not-ameliorate-nephrogenic-diabetes-insipidus-induced-by-lithium-or-potassium-depletion-in-mice(e0d7e613-f397-4759-beb4-c3a57b646dd5).html

Cold exposure causes cell death by depolarization-mediated Ca2+ overload in a chill-susceptible insect

Autor: Camilla Grønkjær, Jeppe Seamus Bayley, Mads Kuhlmann Andersen, Christian Bak Winther, Johannes Overgaard, Ole Bækgaard Nielsen, Thomas Holm Pedersen

Publikováno v: Bayley, J S, Winther, C B, Andersen, M K, Grønkjær, C, Nielsen, O B, Pedersen, T H & Overgaard, J 2018, ' Cold exposure causes cell death by depolarization-mediated Ca2+ overload in a chill-susceptible insect ', Proceedings of the National Academy of Sciences of the United States of America, vol. 115, no. 41, pp. E9737-E9744 . https://doi.org/10.1073/pnas.1813532115

Cold tolerance of insects is arguably among the most important traits defining their geographical distribution. Even so, very little is known regarding the causes of cold injury in this species-rich group. In many insects it has been observed that co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac3cbb35a3f5d31165c3f5b32699cf5c
https://pure.au.dk/portal/da/publications/cold-exposure-causes-cell-death-by-depolarizationmediated-ca2-overload-in-a-chillsusceptible-insect(4ba3c736-9abe-4dcb-b4cc-3a740adf4405).html