Importance of Angomonas deanei KAP4 for kDNA arrangement, cell division and maintenance of the host-bacterium relationship

Autor: Camila Silva Gonçalves, Carolina Moura Costa Catta-Preta, Bruno Repolês, Jeremy C. Mottram, Wanderley De Souza, Carlos Renato Machado, Maria Cristina M. Motta

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)

Abstract Angomonas deanei coevolves in a mutualistic relationship with a symbiotic bacterium that divides in synchronicity with other host cell structures. Trypanosomatid mitochondrial DNA is contained in the kinetoplast and is composed of thousands

Externí odkaz: https://doaj.org/article/f0eb576faa4e4ebe8ab3ae2d334bfcad

Alpha-Tubulin Acetylation in Trypanosoma cruzi: A Dynamic Instability of Microtubules Is Required for Replication and Cell Cycle Progression

Autor: Victoria Lucia Alonso, Mara Emilia Carloni, Camila Silva Gonçalves, Gonzalo Martinez Peralta, Maria Eugenia Chesta, Alejandro Pezza, Luis Emilio Tavernelli, Maria Cristina M. Motta, Esteban Serra

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)

Trypanosomatids have a cytoskeleton arrangement that is simpler than what is found in most eukaryotic cells. However, it is precisely organized and constituted by stable microtubules. Such microtubules compose the mitotic spindle during mitosis, the

Externí odkaz: https://doaj.org/article/940f6f76f0254bb8bfbcfbca4b27e72e

Revisiting the Trypanosoma cruzi metacyclogenesis: morphological and ultrastructural analyses during cell differentiation

Autor: Camila Silva Gonçalves, Andrea Rodrigues Ávila, Wanderley de Souza, Maria Cristina M. Motta, Danielle Pereira Cavalcanti

Publikováno v: Parasites & Vectors, Vol 11, Iss 1, Pp 1-14 (2018)

Abstract Background Trypanosoma cruzi uses several strategies to survive in different hosts. A key step in the life-cycle of this parasite is metacyclogenesis, which involves various morphological, biochemical, and genetic changes that induce the dif

Externí odkaz: https://doaj.org/article/67803b961bf34e64a6089d97f39fd385

Open chromatin analysis inTrypanosoma cruzilife forms highlights critical differences in genomic compartments and developmental regulation at tDNA loci

Autor: Fabiola Barbieri Holetz, M. Carolina Elias, Pedro A. F. Galante, Camila Silva Gonçalves, Loyze Paola Oliveira de Lima, Julia Pinheiro Chagas da Cunha, Ariel Mariano Silber, Saloe Bispo Poubel, Maria Cristina M. Motta, Juliana Nunes Rosón, Alex Ranieri Jerônimo Lima, Héllida Marina Costa-Silva, Herbert Guimarães de Sousa Silva

BackgroundGenomic organization and gene expression regulation in trypanosomes are remarkable because protein-coding genes are organized into codirectional gene clusters with unrelated functions. Moreover, there is no dedicated promoter for each gene,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::867346459c04a81349b89941c8701ac2
https://doi.org/10.1101/2021.10.26.465934

Structure, Properties, and Function of Glycosomes in Trypanosoma cruzi

Autor: Paul A.M. Michels, Maria Cristina M. Motta, Héctor Acosta, Wilfredo Quiñones, Camila Silva Gonçalves, Melisa Gualdrón-López

Publikováno v: Quiñones, W, Acosta, H, Silva Gonçalves, C, Motta, M C, Gualdrón-López, M & Michels, P 2020, ' Structure, properties, and function of glycosomes in trypanosoma cruzi ', Frontiers in Cellular and Infection Microbiology, vol. 10, no. 25 . https://doi.org/10.3389/fcimb.2020.00025
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)

Glycosomes are peroxisome-related organelles that have been identified in kinetoplastids and diplonemids. The hallmark of glycosomes is their harboring of the majority of the glycolytic enzymes. Our biochemical studies and proteome analysis of Trypan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9630b60e68ebdf00c5f689d870b38e45
https://doi.org/10.3389/fcimb.2020.00025