Vector Development Timeline for Mucosal Vaccination and Treatment of Disease Using Lactococcus lactis and Design Approaches of Next Generation Food Grade Plasmids

Autor: Camila Prosperi de Castro, Mariana M. Drumond, Viviane L. Batista, Amanda Nunes, Pamela Mancha-Agresti, Vasco Azevedo

Publikováno v: Frontiers in Microbiology, Vol 9 (2018)

Lactococcus lactis has been used historically in fermentation and food preservation processes as it is considered safe for human consumption (GRAS—Generally Recognized As Safe). Nowadays, in addition to its wide use in the food industry, L. lactis

Externí odkaz: https://doaj.org/article/9f1557c13bbe448d97b896d30f48cf43

Lactococcus lactis FNBPA+ (pValac:e6ag85a) Induces Cellular and Humoral Immune Responses After Oral Immunization of Mice

Autor: Janete Soares Coelho dos Santos, Pamela Mancha-Agresti, Sophie Yvette Leclercq, Tatiane Melo Preisser, Vanessa Pecini da Cunha, Vanessa Bastos Pereira, Meritxell Zurita-Turk, Bianca Mendes Souza, Camila Prosperi de Castro, Anderson Miyoshi, Vasco Azevedo

Publikováno v: Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology

The development of a new vaccine strategy against tuberculosis is urgently needed and has been greatly encouraged by the scientific community worldwide. In this work, we constructed a lactococcal DNA vaccine based on the fusion of two Mycobacterium t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0205a45b3490b866a4f70478511a120
https://www.frontiersin.org/articles/10.3389/fmicb.2021.676172/full

Attenuation of intestinal inflammation in IL-10 deficient mice by a plasmid carrying Lactococcus lactis strain

Autor: Vanessa Bastos Pereira, Tatiane Melo Preisser, Meritxell Zurita-Turk, Anderson Miyoshi, Camila Prosperi de Castro, Bianca Mendes Souza, Ana Maria Caetano Faria, Vanessa Pecini da Cunha, Denise Carmona Cara Machado

Publikováno v: BMC Biotechnology
BMC Biotechnology, Vol 20, Iss 1, Pp 1-12 (2020)

Background Inflammatory bowel diseases (IBD) are intestinal disorders characterized by inflammation in the gastrointestinal tract (GIT) and to date, no efficient treatments exist. Interleukin-10 (IL-10), one of the most important anti-inflammatory cy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4797727667625cebae42daf82e248322
https://doi.org/10.1186/s12896-020-00631-0

DNA Vaccines Approach: From Concepts to Applications

Autor: Pamela Mancha Agresti, Camila Prosperi de Castro, Daniela Santos Pontes, Vanessa Nathalie Pfeiffer, Marcela Santiago Pacheco Azevedo, Tessália Diniz Luerce Saraiva, Fernanda Alvarenga Lima, Anderson Miyoshi, Clarissa Santos Rocha, Vasco Azevedo, Bianca Mendes Souza, Vanessa Bastos Pereira, Meritxell Zurita-Turk

Publikováno v: World Journal of Vaccines. :50-71

DNA vaccines are the third generation vaccines based on purified plasmid preparations containing transgenes that encode antigenic/therapeutic proteins or peptides capable of triggering an immune response against a wide range of diseases. This vaccine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::60e0d9b810465dfb04d8004565f54d85
https://doi.org/10.4236/wjv.2014.42008

Genome Sequence of Lactococcus lactis subsp. lactis NCDO 2118, a GABA-Producing Strain

Autor: Carlos A A Diniz, Anderson Rodrigues dos Santos, Syed Shah Hassan, Lucas Amorim Gonçalves, Vinicius A. C. Abreu, Wendel Renan, Fernanda Alves Dorella, Fábio Miranda, Carlos Augusto Gomes Leal, Tessália Diniz Luerce Saraiva, Anne Cybelle Pinto, Diego Mariano, Camila Prosperi de Castro, Vanessa Bastos Pereira, Ulisses de Pádua Pereira, Bianca Mendes Souza, Anderson Miyoshi, Edson Luiz Folador, Vasco Azevedo, Letícia de Castro Oliveira, Sandeep Tiwari, Luis C. Guimarães, Renata F. Silva, Clarissa Santos Rocha, Sintia Almeida, Edgar L. Aguiar, Pamela Mancha Agresti, Flávia Figueira Aburjaile, Henrique César Pereira Figueiredo, Marcela Santiago Pacheco de Azevedo, Siomar de Castro Soares, Felipe L. Pereira, Rommel Thiago Jucá Ramos, Eudes Barbosa, Artur Silva, Adriana Ribeiro Carneiro, Matheus Freire, Alex F. Carvalho, Alberto Fernandes de Oliveira Junior, Pablo H. C. Sá

Publikováno v: Oliveira, L C, Saraiva, T D L, Soares, S C, Ramos, R T J, Sá, P H C G, Carneiro, A R, Miranda, F, Freire, M, Renan, W, Júnior, A F O, Santos, A R, Pinto, A C, Souza, B M, Castro, C P, Diniz, C A A, Rocha, C S, Mariano, D C B, de Aguiar, E L, Folador, E L, Barbosa, E, Aburjaile, F F, Gonçalves, L A, Guimarães, L C, Azevedo, M, Agresti, P C M, Silva, R F, Tiwari, S, Almeida, S S, Hassan, S S, Pereira, V B, Abreu, V A C, Pereira, U P, Dorella, F A, Carvalho, A F, Pereira, F L, Leal, C A G, Figueiredo, H C P, Silva, A, Miyoshi, A & Azevedo, V 2014, ' Genome Sequence of Lactococcus lactis subsp. lactis NCDO 2118, a GABA-Producing Strain ', Genome Announcements, vol. 2, no. 5, e00980-14 . https://doi.org/10.1128/genomeA.00980-14
Genome Announcements

Lactococcus lactis subsp. lactis NCDO 2118 is a nondairy lactic acid bacterium, a xylose fermenter, and a gamma-aminobutyric acid (GABA) producer isolated from frozen peas. Here, we report the complete genome sequence of L. lactis NCDO 2118, a strain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a95556a43fe1f078d72293ef050aa42
https://portal.findresearcher.sdu.dk/da/publications/7563b43c-1387-482d-a636-ee48f9f4d5eb