Acetylsalicylic acid and dihydroartemisinin combined therapy on experimental malaria-associated acute lung injury: analysis of lung function and the inflammatory process

Autor: Helena D’Anunciação de Oliveira, Camila Nunes Batista, Maiara Nascimento Lima, Ana Carolina Lima, Beatriz Amanda Barbosa Rangel dos Passos, Rodrigo Jose Rocha Xavier Freitas, Johnatas Dutra Silva, Debora Gonçalves Xisto, Marcos Vinícius Rangel-Ferreira, Marcelo Pelajo, Patricia Rieken Macedo Rocco, Flávia Lima Ribeiro-Gomes, Hugo Caire de Castro Faria-Neto, Tatiana Maron-Gutierrez

Publikováno v: Malaria Journal, Vol 23, Iss 1, Pp 1-14 (2024)

Abstract Background Severe malaria can cause respiratory symptoms, which may lead to malaria-acute lung injury (MA-ALI) due to inflammation and damage to the blood-gas barrier. Patients with severe malaria also often present thrombocytopenia, and the

Externí odkaz: https://doaj.org/article/3e638df23889482182888072dd2634ff

Partial characterization of Plasmodium falciparum trophozoite proteome under treatment with quinine, mefloquine and the natural antiplasmodial diosgenone

Autor: Camila Nunes-Batista, Cesar Segura, Mariano G. Zalis, Wanda M. A. von Krüger, Paulo Mascarello Bisch, Yesid Cuesta-Astroz

Publikováno v: Biomédica, Volume: 34, Issue: 2, Pages: 237-249, Published: JUN 2014
Biomédica: revista del Instituto Nacional de Salud, Vol 34, Iss 2, Pp 237-49 (2014)

Introduction: Despite efforts to control malaria, around 10% of the world population is at risk of acquiring this disease. Plasmodium falciparum accounts for the majority of severe cases and deaths. Malaria control programs have failed due to the the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa26b1bb35a1cfdc735dedcaf2f947bd
https://doi.org/10.7705/biomedica.v34i2.1700

In vitro-reduced susceptibility to artemether in P. falciparum and its association with polymorphisms on transporter genes

Autor: Christian T. Happi, Rodrigo Brindeiro, A. Sowunmi, Dyann F. Wirth, Elieth A. Mesquita, Amilcar Tanuri, Camila Nunes Batista, Mariano G. Zalis, Carolina Bustamante, Claudio J. Struchiner, Onikepe A. Folarin, Ayoade M. J. Oduola, Grace O. Gbotosho

Publikováno v: The Journal of infectious diseases. 206(3)

Plasmodium falciparum with reduced sensitivity to artemisinin derivatives has been observed in endemic areas, but the molecular mechanisms for this reduced sensitivity remain unclear. We evaluated the association between in vitro susceptibility of P.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52dafcf06ed99426e96780d1150a49cc
https://pubmed.ncbi.nlm.nih.gov/22615315