Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Camila Iansen Irion"'
Autor:
Monique Williams, Jose Manuel Condor Capcha, Camila Iansen Irion, Grace Seo, Guerline Lambert, Ali Kamiar, Keyvan Yousefi, Rosemeire Kanashiro‐Takeuchi, Lauro Takeuchi, Ali G. Saad, Armando Mendez, Keith A. Webster, Jeffrey J. Goldberger, Joshua M. Hare, Lina A. Shehadeh
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 17 (2022)
Background The pathways of diastolic dysfunction and heart failure with preserved ejection fraction driven by lipotoxicity with metabolic syndrome are incompletely understood. Thus, there is an urgent need for animal models that accurately mimic the
Externí odkaz:
https://doaj.org/article/432212ebf6704b49a53ed9538b43891e
Autor:
Valentina Dargam, Hooi Hooi Ng, Sana Nasim, Daniel Chaparro, Camila Iansen Irion, Suhas Rathna Seshadri, Armando Barreto, Zachary C. Danziger, Lina A. Shehadeh, Joshua D. Hutcheson
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundCalcific aortic valve disease (CAVD) is often undiagnosed in asymptomatic patients, especially in underserved populations. Although artificial intelligence has improved murmur detection in auscultation exams, murmur manifestation depends on
Externí odkaz:
https://doaj.org/article/b3a8ac504ace4d16acb35e1c707cd4d2
Autor:
Camila Iansen Irion, Julian C. Dunkley, Krista John-Williams, José Manuel Condor Capcha, Serene A. Shehadeh, Andre Pinto, Matthias Loebe, Keith A. Webster, Nicolas A. Brozzi, Lina A. Shehadeh
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
BackgroundHeart transplant is the gold standard therapy for patients with advanced heart failure. Over 5,500 heart transplants are performed every year worldwide. Cardiac allograft vasculopathy (CAV) is a common complication post-heart transplant whi
Externí odkaz:
https://doaj.org/article/0316fc2c19f145d097b3e555a08a813d
Autor:
Jessica Hersh, José Manuel Condor Capcha, Camila Iansen Irion, Guerline Lambert, Mauricio Noguera, Mohit Singh, Avinash Kaur, Emre Dikici, Joaquín J. Jiménez, Lina A. Shehadeh, Sylvia Daunert, Sapna K. Deo
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2159 (2021)
Gene therapy is a good alternative for determined congenital disorders; however, there are numerous limitations for gene delivery in vivo including targeted cellular uptake, intracellular trafficking, and transport through the nuclear membrane. Here,
Externí odkaz:
https://doaj.org/article/5b61c16d76904abfbf7887827be7af44
Osteopontin Expression in Cardiomyocytes Is Increased in Pediatric Patients With Sepsis or Pneumonia
Autor:
Camila Iansen Irion, Kiera Parrish, Krista John-Williams, Sakir H. Gultekin, Lina A. Shehadeh
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Sepsis and pneumonia are major causes of death in the United States, and their pathophysiology includes infection with inflammation and immune dysfunction. Both sepsis and pneumonia cause cardiovascular dysfunction. The expression of Osteopontin (OPN
Externí odkaz:
https://doaj.org/article/073c5b47cd804ab1a2892c264003df13
Autor:
Camila Iansen Irion, Bruno Diaz Paredes, Guilherme Visconde Brasil, Sandro Torrentes da Cunha, Luis Felipe Paula, Alysson Roncally Carvalho, Antonio Carlos Campos de Carvalho, Adriana Bastos Carvalho, Regina Coeli dos Santos Goldenberg
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 112, Iss 8, Pp 551-560
BACKGROUND Chagas disease is a public health problem caused by infection with the protozoan Trypanosoma cruzi. There is currently no effective therapy for Chagas disease. Although there is some evidence for the beneficial effect of bone marrow-derive
Externí odkaz:
https://doaj.org/article/bc85ee6e340d403fb91d8e70ee9c8cb6
Autor:
Julian C. Dunkley, Serene A. Shehadeh, Keith A. Webster, Guerline Lambert, Krista John-Williams, Jeffrey J. Goldberger, Lina A. Shehadeh, Camila Iansen Irion, Keyvan Yousefi
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 320:H1862-H1872
In an Alport mouse model of heart failure with preserved ejection fraction (HFpEF), exercise and carvedilol synergistically improved systolic function without affecting diastole. Carvedilol alone or in combination with exercise also improved kidney f
Autor:
Jose Manuel Condor Capcha, Camila Iansen Irion, Guerline Lambert, AHMED CHAHDI, Peter Buchwald, Derek Dykxhoorn, Hamidreza Farzaneh, Sapna deo, Sylvia Daunert, Karen C Young, Lina A Shehadeh
Publikováno v:
Circulation. 144
Introduction: People with previous CVD hospitalized for COVID-19 have elevated death rate. We reported that patients with diabetes and HF higher protein levels of the low density lipoprotein receptor (LDLR). We hypothesized that LDLR is a novel host
Autor:
Valentina Dargam, Hooi H Ng, Sana Nasim, Camila Iansen Irion, Suhas Seshadri, Lina A Shehadeh, Joshua Hutcheson
Publikováno v:
Circulation. 144
Introduction: Heart valve diseases (HVDs) often remain undiagnosed until late stages, especially in underserved populations, leading to significant comorbidities. Artificial intelligence has improved murmur detection in digital phonocardiograms (PCG)
Autor:
Monique Williams, Camila Iansen Irion, Jose Manuel Condor Capcha, Guerline Lambert, Grace Seo, Jeffrey J Goldberger, Lina A Shehadeh
Publikováno v:
Circulation. 144
Background: Hyperlipidemia is a major risk factor for CVD. Patients with HF with preserved ejection fraction (HFpEF) have more myocardial lipid accumulation than patients with reduced EF (HFrEF). RNASeq data from cardiac biopsies showed downregulatio