Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Camila Cardoso-Santos"'
Autor:
Dorien Mabille, Camila Cardoso Santos, Rik Hendrickx, Mathieu Claes, Peter Takac, Christine Clayton, Sarah Hendrickx, Fabian Hulpia, Louis Maes, Serge Van Calenbergh, Guy Caljon
Publikováno v:
Microorganisms, Vol 9, Iss 4, p 826 (2021)
Human African trypanosomiasis is a neglected parasitic disease for which the current treatment options are quite limited. Trypanosomes are not able to synthesize purines de novo and thus solely depend on purine salvage from the host environment. This
Externí odkaz:
https://doaj.org/article/297c4da012bb407399bfa62aa9b015d0
Autor:
Tummala Rama Krishna Reddy, Marcos Meuser Batista, Asma Inam Ullah, Camila Cardoso Santos, Maria de Nazaré Correia Soeiro
Publikováno v:
Parasitology. 148:98-104
Cutaneous leishmaniasis (CL) is one of the most disregarded tropical neglected disease with the occurrence of self-limiting ulcers and triggering mucosal damage and stigmatizing scars, leading to huge public health problems and social negative impact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a21d8ea436f26ca1c610f94069461ae3
https://doi.org/10.1017/s0031182020001900
https://doi.org/10.1017/s0031182020001900
Autor:
Natália Lins da Silva Gomes, Camila Cardoso-Santos, Ana Lia Mazzeti, Ludmila Ferreira de Almeida Fiuza, Denise da Gama Jaen Batista, Cristiane França da Silva, Serge Van Calenbergh, Maria de Nazaré Correia Soeiro, Guy Caljon, Otacilio C. Moreira, Gabriel Melo de Oliveira, Louis Maes, Fabian Hulpia, Roberson Donola Girão
Publikováno v:
JAC-ANTIMICROBIAL RESISTANCE
JAC-Antimicrobial Resistance
JAC-Antimicrobial Resistance
Background The protozoan Trypanosoma cruzi is auxotrophic for purines and causes Chagas’ disease (CD), a neglected illness affecting >6 million people. Combining the 3-deoxyribofuranose part of cordycepin with the modified purine ring of a nucleosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1731847b948decd661e97223fc6ed64e
https://doi.org/10.1093/jacamr/dlab168
https://doi.org/10.1093/jacamr/dlab168
Autor:
Camila, Cardoso-Santos, Ludmila, Ferreira de Almeida Fiuza, Cristiane, França da Silva, Ana Lia, Mazzeti, Roberson, Donola Girão, Gabriel, Melo de Oliveira, Denise, da Gama Jaen Batista, Otacilio, Cruz Moreira, Natália, Lins da Silva Gomes, Louis, Maes, Guy, Caljon, Fabian, Hulpia, Serge V, Calenbergh, Maria de Nazaré, Correia Soeiro
Publikováno v:
JAC-Antimicrobial Resistance
Background The protozoan Trypanosoma cruzi is auxotrophic for purines and causes Chagas’ disease (CD), a neglected illness affecting >6 million people. Combining the 3-deoxyribofuranose part of cordycepin with the modified purine ring of a nucleosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d5bc5c8641b80fbd32683fb5beec9c6c
https://pubmed.ncbi.nlm.nih.gov/34806007
https://pubmed.ncbi.nlm.nih.gov/34806007
Autor:
Edson Roberto da Silva, Camila Cardoso-Santos, Lucas Villas Bôas Hoelz, Julio Abel Alfredo dos Santos Simone Come, Nubia Boechat, Lívia M. Feitosa, Danielle L. Souza, Maria de Nazaré Correia Soeiro, Luiz C. S. Pinheiro, Marcos Meuser Batista
Publikováno v:
Bioorganic & Medicinal Chemistry. 27:3061-3069
Arginase performs the first enzymatic step in polyamine biosynthesis in Leishmania and represents a promising target for drug development. Polyamines in Leishmania are involved in trypanothione synthesis, which neutralize the oxidative burst of react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4483d867f7e8c2f300a4b800a36c634
https://doi.org/10.1016/j.bmc.2019.05.026
https://doi.org/10.1016/j.bmc.2019.05.026
Autor:
Jakob, Bouton, Ludmila, Ferreira de Almeida Fiuza, Camila, Cardoso Santos, Maria Angela, Mazzarella, Maria de Nazaré Correia, Soeiro, Louis, Maes, Izet, Karalic, Guy, Caljon, Serge, Van Calenbergh
Publikováno v:
Journal of medicinal chemistry. 64(7)
Chagas disease and visceral leishmaniasis are two neglected tropical diseases responsible for numerous deaths around the world. For both, current treatments are largely inadequate, resulting in a continued need for new drug discovery. As both kinetop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7976eeb282d3cbf02788632b336476be
https://pubmed.ncbi.nlm.nih.gov/33784107
https://pubmed.ncbi.nlm.nih.gov/33784107
Autor:
Ludmila Ferreira de Almeida Fiuza, Cai Lin, Camila Cardoso Santos, Jakob Bouton, Guy Caljon, Serge Van Calenbergh, Maria de Nazaré Correia Soeiro, Louis Maes, Fabian Hulpia, Otacilio C. Moreira, Izet Karalic, Daniela Ferreira Nunes
Publikováno v:
ChemMedChem
Chagas disease is a tropical infectious disease resulting in progressive organ-damage and currently lacks efficient treatment and vaccine options. The causative pathogen, Trypanosoma cruzi, requires uptake and processing of preformed purines from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79e1e9661ab58e87a9b003924809a29
https://pubmed.ncbi.nlm.nih.gov/33856742
https://pubmed.ncbi.nlm.nih.gov/33856742
Autor:
Maria Angela Mazzarella, Camila Cardoso Santos, Serge Van Calenbergh, Maria de Nazaré Correia Soeiro, Izet Karalic, Guy Caljon, Louis Maes, Jakob Bouton, Ludmila Ferreira de Almeida Fiuza
Publikováno v:
Journal of medicinal chemistry
Chagas disease and visceral leishmaniasis are two neglected tropical diseases responsible for numerous deaths around the world. For both, current treatments are largely inadequate, resulting in a continued need for new drug discovery. As both kinetop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb46dcee8897f9727b0c27b58b1796eb
Autor:
Natália Lins da Silva-Gomes, Ifedayo Victor Ogungbe, Marcos Meuser Batista, Kelly Cristina Demarque, Camila Cardoso Santos, Huaisheng Zhang, Gabriel Melo de Oliveira, Otacilio C. Moreira, Maria de Nazaré Correia Soeiro
Publikováno v:
Antimicrob Agents Chemother
Phenotypic assay against Leishmania amazonensis in vitro and in vivo led to identification of an adamantyl-based phenyl sulfonyl acetamide (compound 1) as a promising antileishmanial agent. Compound 1 inhibited the growth of intracellular forms of L.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a64603b375d48d544e12e72b0bca773
https://europepmc.org/articles/PMC7674027/
https://europepmc.org/articles/PMC7674027/
Autor:
Camila, Cardoso Santos, Marcos, Meuser Batista, Asma, Inam Ullah, Tummala, Rama Krishna Reddy, Maria de Nazaré Correia, Soeiro
Publikováno v:
Parasitology. 148(1)
Cutaneous leishmaniasis (CL) is one of the most disregarded tropical neglected disease with the occurrence of self-limiting ulcers and triggering mucosal damage and stigmatizing scars, leading to huge public health problems and social negative impact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f0d3c03de5e9a483544bcbd059598b7c
https://pubmed.ncbi.nlm.nih.gov/33023678
https://pubmed.ncbi.nlm.nih.gov/33023678