Valproic acid attenuates hyperglycemia-induced complement and coagulation cascade gene expression

Autor: Assam El-Osta, Marina Barreto Felisbino, Camila Borges Martins Oliveira, Ishant Khurana, Maria Luiza S. Mello, Mark Ziemann

Atherothrombosis remains the leading cause of morbidity and mortality in patients diagnosed with diabetes mellitus, but the molecular mechanisms underpinning this remain unresolved. As the liver plays a major role in metabolic homeostasis and secreti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0cce0332158c7cfac541dffda81113
https://doi.org/10.1101/253591

Association of CYP1A1 A4889G and T6235C polymorphisms with the risk of sporadic breast cancer in Brazilian women

Autor: Cassio Cardoso-Filho, Gustavo Jacob Lourenço, Leonardo Da Silveira Bossi, Maria Salete Costa-Gurgel, Carmen Silvia Passos Lima, Camila Borges Martins Oliveira

Publikováno v: Clinics; v. 70 n. 10 (2015); 680-685
Clinics; Vol. 70 Núm. 10 (2015); 680-685
Clinics; Vol. 70 No. 10 (2015); 680-685
Clinics
Universidade de São Paulo (USP)
instacron:USP
Clinics, Volume: 70, Issue: 10, Pages: 680-685, Published: OCT 2015
Clinics, Vol 70, Iss 10, Pp 680-685 (2015)

OBJECTIVES: We examined the influence of CYP1A1 A4889G and T6235C polymorphisms on the risk of sporadic breast cancer. METHOD: DNA from 742 sporadic breast cancer patients and 742 controls was analyzed using the polymerase chain reaction, followed by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc5917bf3ed45b492883395d2cb1124b
https://www.revistas.usp.br/clinics/article/view/106665

Clinical effects of A4889G and T6235C polymorphisms in cytochrome P-450 CYP1A1 for breast cancer patients treated with tamoxifen: implications for tumor aggressiveness and patient survival

Autor: Carmen Silvia Passos Lima, Cassio Cardoso-Filho, Maria Salete Costa Gurgel, Camila Borges Martins Oliveira, Luis Otávio Sarian, Leonardo Da Silveira Bossi, Gustavo Jacob Lourenço

Publikováno v: Cancer chemotherapy and pharmacology. 72(3)

Individual differences in cytochrome P-450 efficiency partly explain their variations in resistance to tamoxifen and estrogen metabolism. Two polymorphisms of the CYP1A1 gene-A4889G and T6235C-are known to affect activation of estrone and estradiol a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fda0c0eb981fc701112627ddd7ca9a5
https://pubmed.ncbi.nlm.nih.gov/23842721

Association of FASL and FAS polymorphisms, enrolled in extrinsic apoptosis pathway, with head and neck squamous cell carcinoma risk and outcomes

Autor: Camila Borges Martins Oliveira, Guilherme Nogueira, Vitor Teixeira Liutti, Gustavo Jacob Lourenço, Leisa Lopes-Aguiar, Ericka Francislaine Dias Costa, Tathiane Regine Penna Lima, José Augusto Rinck, Carmen Silvia Passos Lima, Frederico Leal, Vivian Antunes Santos

Publikováno v: Journal of Clinical Oncology. 34:6053-6053

6053Background: Apoptosis plays an important role in origin of head and neck squamous cell carcinoma (HNSCC). Inherited genetic alterations, such as single nucleotide polymorphisms (SNPs), may infl...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca77d3eea4b4b78d8770d23bbf235f1b
https://doi.org/10.1200/jco.2016.34.15_suppl.6053

Association of Erp29 Genetic Polymorphism with Breast Cancer Risk and Prognosis

Autor: Gustavo Jacob Lourenço, Maria Salete Costa-Gurgel, Cassio Cardoso-Filho, Leonardo Da Silveira Bossi, C. Oliveira, C.S.P. Lima, Camila Borges Martins Oliveira, Luis Otávio Sarian

Publikováno v: Annals of Oncology. 25:iv93

Aim: ERP29, a tumor suppressor gene, was related with the onset of tumors. The influence of ERP29 c.*293A > G (rs7114) polymorphism in breast cancer (BC) risk and prognosis has never been performed before and was the aim of this study. Methods: We an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a9e980fcbea50f882fdadd349547eca
https://doi.org/10.1093/annonc/mdu327.24