Zobrazeno 1 - 10
of 26 587
pro vyhledávání: '"Cami"'
Autor:
Buwei Huang, Brian Coventry, Marta T. Borowska, Dimitrios C. Arhontoulis, Marc Exposit, Mohamad Abedi, Kevin M. Jude, Samer F. Halabiya, Aza Allen, Cami Cordray, Inna Goreshnik, Maggie Ahlrichs, Sidney Chan, Hillary Tunggal, Michelle DeWitt, Nathaniel Hyams, Lauren Carter, Lance Stewart, Deborah H. Fuller, Ying Mei, K. Christopher Garcia, David Baker
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Cytokine release syndrome (CRS), commonly known as cytokine storm, is an acute systemic inflammatory response that is a significant global health threat. Interleukin-6 (IL-6) and interleukin-1 (IL-1) are key pro-inflammatory cytokines involv
Externí odkaz:
https://doaj.org/article/5f93a3f590e5444ea2f8d8872b6aedb3
Autor:
Anna R. Mahr, Maia M. C. Bennett-Boehm, Frederik H. Rothemejer, Isabelle S. Weber, Alexander K. Regan, Josh Q. Franzen, Cami R. Bisson, Angela N. Truong, Rikke Olesen, Mariane H. Schleimann, Claudia M. Rauter, Audrey L. Smith, Dalia El-Gamal, Ole S. Søgaard, Martin Tolstrup, Paul W. Denton
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract There are two known mechanisms by which natural killer (NK) cells recognize and kill diseased targets: (i) direct killing and (ii) antibody-dependent cell-mediated cytotoxicity (ADCC). We investigated an indirect NK cell activation strategy
Externí odkaz:
https://doaj.org/article/85906b314a2a4acaaca1f37e36865354
Autor:
Huimin Yan, Paola Gonzalo-Encabo, Rebekah L. Wilson, Cami N. Christopher, James D. Cannon, Dong-Woo Kang, John Gardiner, Michelle Perez, Mary K. Norris, Daniel Gundersen, Laura L. Hayman, Rachel A. Freedman, Timothy R. Rebbeck, Ling Shi, Christina M. Dieli-Conwright
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundHigher rates of physical inactivity and comorbid conditions are reported in Hispanic/Latinx and Black cancer patients receiving chemotherapy compared to their White counterparts. Despite the beneficial effect of exercise training for cancer
Externí odkaz:
https://doaj.org/article/91538c0128c94ca2866033d371c70f90
Autor:
Josien Lanfermeijer, Koen van de Ven, Harry van Dijken, Marion Hendriks, Cami M. P. Talavera Ormeño, Femke de Heij, Paul Roholl, José A. M. Borghans, Debbie van Baarle, Jørgen de Jonge
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract CD8 + T cells are promising targets for vaccination against influenza A virus (IAV) infection. Their induction via peptide vaccination is not trivial, because peptides are weakly immunogenic. One strategy to overcome this is by vaccination w
Externí odkaz:
https://doaj.org/article/dcf333a662a7405bb9eb73687aa9e066
Autor:
Maia M.C. Bennett-Boehm, Anna R. Mahr, Sean T. Hartwell, Alexander K. Regan, Isabelle S. Weber, Arriana Blackmon, Cami R. Bisson, Angela N. Truong, Bella A. Circo, Jaden Nienhueser, Donald R. Rogers, Nathan Booher, Nithya Rajagopalan, Jacob W.S. Martens, Paul W. Denton
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e22991- (2023)
Assays to quantify natural killer (NK) cell killing efficacy have traditionally focused on assessing either direct killing or antibody dependent cell-mediated cytotoxicity (ADCC) independently. Due to the probability that immunotherapeutic interventi
Externí odkaz:
https://doaj.org/article/52f9824e6b284dbb989cfb03dc833e9e
Autor:
Bianca D. M. van Tol, Bjorn R. van Doodewaerd, Guinevere S. M. Lageveen-Kammeijer, Bas C. Jansen, Cami M. P. Talavera Ormeño, Paul J. M. Hekking, Aysegul Sapmaz, Robbert Q. Kim, Angeliki Moutsiopoulou, David Komander, Manfred Wuhrer, Gerbrand J. van der Heden van Noort, Huib Ovaa, Paul P. Geurink
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Most insights into deubiquitinase (DUB) substrate specificity originate from studies with isolated di-ubiquitins (diUb), but in cells diUbs with different linkage types coexist. Here, the authors develop a mass spectrometric DUB activity assay that c
Externí odkaz:
https://doaj.org/article/2c3b7930e79a4065a586ae1d307ad567
Autor:
Richard S. Nho, Cami Rice, Jayendra Prasad, Hannah Bone, Laszlo Farkas, Mauricio Rojas, Jeffrey C. Horowitz
Publikováno v:
Physiological Reports, Vol 11, Iss 17, Pp n/a-n/a (2023)
Abstract Hypoxia, a state of insufficient oxygen availability, promotes cellular lactate production. Lactate levels are increased in lungs from patients with idiopathic pulmonary fibrosis (IPF), a disease characterized by excessive scar formation, an
Externí odkaz:
https://doaj.org/article/5a709e79e4994df8a6a0a8536a2e0f4a
Publikováno v:
Frontiers in Psychology, Vol 14 (2023)
IntroductionThere is increasing recognition of the mental health burden of climate change and the effects on general well-being, even in those who have not (yet) experienced direct impacts. Climate anxiety, which is prominent among young people in pa
Externí odkaz:
https://doaj.org/article/ae5b8c73ccec4f8f8497250cf9a63b48
Publikováno v:
Digital Business, Vol 3, Iss 1, Pp 100051- (2023)
Knowledge work today is characterized by frequent interruptions. Digital distraction plays an increasingly important role in this work context as workers' behavior and emotional state online spills into work practices, causing stress and productivity
Externí odkaz:
https://doaj.org/article/e0d444d86a22407a87b0861afbfec676
Autor:
David Lubkowicz, Nicholas G Horvath, Michael J James, Pasquale Cantarella, Lauren Renaud, Christopher G Bergeron, Ron B Shmueli, Cami Anderson, Jian‐Rong Gao, Caroline B Kurtz, Mylene Perreault, Mark R Charbonneau, Vincent M Isabella, David L Hava
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 3, Pp 1-17 (2022)
Abstract Enteric hyperoxaluria (EH) is a metabolic disease caused by excessive absorption of dietary oxalate leading to the formation of chronic kidney stones and kidney failure. There are no approved pharmaceutical treatments for EH. SYNB8802 is an
Externí odkaz:
https://doaj.org/article/b6d895d2871d4ce49bd1ee066df28241