Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Cameron Sullards"'
Autor:
Alfred H. Merrill, Dennis C. Liotta, Dirck L. Dillehay, M. Cameron Sullards, Sarah T. Pruett, Jeremy C. Allegood, Suzanne G. Mays, Harsha Ramaraju, Qiong Peng, Anatoliy Bushnev, Holly Symolon
Supplementary Methods and Results from Enigmol: A Novel Sphingolipid Analogue with Anticancer Activity against Cancer Cell Lines and In vivo Models for Intestinal and Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53635582c1aab65452d6dd31168e961c
https://doi.org/10.1158/1535-7163.22502079
https://doi.org/10.1158/1535-7163.22502079
Autor:
Alfred H. Merrill, Dennis C. Liotta, Dirck L. Dillehay, M. Cameron Sullards, Sarah T. Pruett, Jeremy C. Allegood, Suzanne G. Mays, Harsha Ramaraju, Qiong Peng, Anatoliy Bushnev, Holly Symolon
Supplementary Figures 1-6 from Enigmol: A Novel Sphingolipid Analogue with Anticancer Activity against Cancer Cell Lines and In vivo Models for Intestinal and Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec397518129adf12f4a11a6f645182a
https://doi.org/10.1158/1535-7163.22502085
https://doi.org/10.1158/1535-7163.22502085
Autor:
Alfred H. Merrill, Dennis C. Liotta, Dirck L. Dillehay, M. Cameron Sullards, Sarah T. Pruett, Jeremy C. Allegood, Suzanne G. Mays, Harsha Ramaraju, Qiong Peng, Anatoliy Bushnev, Holly Symolon
Supplementary Material from Enigmol: A Novel Sphingolipid Analogue with Anticancer Activity against Cancer Cell Lines and In vivo Models for Intestinal and Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43de3ce1c522b807c7c6aca2d1619f79
https://doi.org/10.1158/1535-7163.22502082.v1
https://doi.org/10.1158/1535-7163.22502082.v1
Autor:
Christopher A. Haynes, Jeremy C. Allegood, Elaine W. Wang, Samuel L. Kelly, M. Cameron Sullards, Jr. Alfred H. Merrill
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 8, Pp 1583-1594 (2011)
This study describes the use of a stable-isotope labeled precursor ([U-13C]palmitate) to analyze de novo sphingolipid biosynthesis by tandem mass spectrometry. It also describes factors to consider in interpreting the data, including the isotope's lo
Externí odkaz:
https://doaj.org/article/5098d3a860d34c1c9ae59356319eea1e
Autor:
Rebecca L. Shaner, Jeremy C. Allegood, Hyejung Park, Elaine Wang, Samuel Kelly, Christopher A. Haynes, M. Cameron Sullards, Alfred H. Merrill, Jr.
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 8, Pp 1692-1707 (2009)
Sphingolipids are a highly diverse category of bioactive compounds. This article describes methods that have been validated for the extraction, liquid chromatographic (LC) separation, identification and quantitation of sphingolipids by electrospray i
Externí odkaz:
https://doaj.org/article/91c8f1bb103241538320254cabf61a47
Autor:
Sarah T. Pruett, Anatoliy Bushnev, Kerri Hagedorn, Madhura Adiga, Christopher A. Haynes, M. Cameron Sullards, Dennis C. Liotta, Alfred H. Merrill, Jr.
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 8, Pp 1621-1639 (2008)
“Sphingosin” was first described by J. L. W. Thudichum in 1884 and structurally characterized as 2S,3R,4E-2-aminooctadec-4-ene-1,3-diol in 1947 by Herb Carter, who also proposed the designation of “lipides derived from sphingosine as sphingolip
Externí odkaz:
https://doaj.org/article/3a4d6d1be7564f24b6416634e47d1a16
Autor:
Christopher A. Haynes, Jeremy C. Allegood, Kacee Sims, Elaine W. Wang, M. Cameron Sullards, Alfred H. Merrill, Jr.
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 5, Pp 1113-1125 (2008)
Fatty acyl-CoAs participate in numerous cellular processes. This article describes a method for the quantitation of subpicomole amounts of long-chain and very-long-chain fatty acyl-CoAs by reverse-phase LC combined with electrospray ionization tandem
Externí odkaz:
https://doaj.org/article/b42f584bd718495c92d74e94e01dfa00
Autor:
Alfred H. Merrill, Jr., Todd H. Stokes, Amin Momin, Hyejung Park, Brent J. Portz, Samuel Kelly, Elaine Wang, M. Cameron Sullards, May Dongmei Wang
Publikováno v:
Journal of Lipid Research, Vol 50, Iss , Pp S97-S102 (2009)
The sphingolipidome is the portion of the lipidome that encompasses all sphingoid bases and their derivatives. Whereas the most studied sphingoid base is sphingosine [(2S,3R,4E)-2-aminooctadecene-1,3-diol], mammals have dozens of structural variants,
Externí odkaz:
https://doaj.org/article/afc13dd991ce4706a9114fdd7d58d96c
Autor:
M. Cameron Sullards, Alfred H. Merrill
A challenge for sphingolipidomic analysis is the vast number of subspecies, including a large number of isomers-a complication that was even appreciated by the original discoverer of sphingolipids J. L. W. Thudichum (The Chemistry of the Brain, p. x,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::971217329b6e7c389e23558dc737ec72
https://europepmc.org/articles/PMC5476497/
https://europepmc.org/articles/PMC5476497/
Autor:
Oswald Quehenberger, Kaoru Saijo, Christopher S. Morello, H. Alex Brown, David W. Russell, Eoin Fahy, Jeffrey G. McDonald, Norihito Shibata, M. Cameron Sullards, Jesse N. Fox, Michael T. Lam, Andrea Crotti, Robert C. Murphy, Casey E. Romanoski, Nathanael J. Spann, Alfred H. Merrill, Edward A. Dennis, Shankar Subramaniam, Christian R. H. Raetz, Deborah H. Spector, Donna Reichart, Minna U. Kaikkonen, Christopher K. Glass, Aaron F. Carlin, Douglas R. Cavener, Mano Ram Maurya
Publikováno v:
The Journal of biological chemistry, vol 288, iss 50
25-Hydroxycholesterol (25OHC) is an enzymatically derived oxidation product of cholesterol that modulates lipid metabolism and immunity. 25OHC is synthesized in response to interferons and exerts broad antiviral activity by as yet poorly characterize