A Unified Approach to Analysis of MRI Radiomics of Glioma Using Minimum Spanning Trees

Autor: Olivier B. Simon, Rajan Jain, Yoon-Seong Choi, Carsten Görg, Krithika Suresh, Cameron Severn, Debashis Ghosh

Publikováno v: Frontiers in Physics, Vol 10 (2022)

Radiomics has shown great promise in detecting important genetic markers involved in cancers such as gliomas, as specific mutations produce subtle but characteristic changes in tumor texture and morphology. In particular, mutations in IDH (isocitrate

Externí odkaz: https://doaj.org/article/f36a46b948014fc7953c27c793dcfcd4

A Pipeline for the Implementation and Visualization of Explainable Machine Learning for Medical Imaging Using Radiomics Features

Autor: Cameron Severn, Krithika Suresh, Carsten Görg, Yoon Seong Choi, Rajan Jain, Debashis Ghosh

Publikováno v: Sensors, Vol 22, Iss 14, p 5205 (2022)

Machine learning (ML) models have been shown to predict the presence of clinical factors from medical imaging with remarkable accuracy. However, these complex models can be difficult to interpret and are often criticized as “black boxes”. Predict

Externí odkaz: https://doaj.org/article/1193bfa45e91405c8e6a4070c6c45690

Tubular injury in diabetic ketoacidosis: Results from the diabetic kidney alarm study

Autor: Daniël H. van Raalte, Richard J. Johnson, David Z.I. Cherney, Meda E. Pavkov, Wassim Obeid, Laura Pyle, Miguel A. Lanaspa, Chirag R. Parikh, Federica Piani, Linh T. Chung, Isabella Melena, Carissa Vinovskis, Kristen J. Nadeau, Robert G. Nelson, Cameron Severn, Petter Bjornstad, Carlos A. Roncal-Jimenez, Arleta Rewers

Publikováno v: Pediatr Diabetes
Pediatric Diabetes, 22(7), 1031-1039. Blackwell Munksgaard
Piani, F, Melena, I, Severn, C, Chung, L T, Vinovskis, C, Cherney, D, Pyle, L, Roncal-Jimenez, C A, Lanaspa, M A, Rewers, A, van Raalte, D H, Obeid, W, Parikh, C, Nelson, R G, Pavkov, M E, Nadeau, K J, Johnson, R J & Bjornstad, P 2021, ' Tubular injury in diabetic ketoacidosis: Results from the diabetic kidney alarm study ', Pediatric Diabetes, vol. 22, no. 7, pp. 1031-1039 . https://doi.org/10.1111/pedi.13259

Objective: Glomerular injury is a recognized complication of diabetic ketoacidosis (DKA), yet the tubular lesions are poorly understood. The aim of this prospective study was to evaluate the presence and reversibility of tubular injury during DKA in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312046b28b04ccf6a6f7edf82b1e2df4
https://doi.org/10.1111/pedi.13259

Aminoaciduria and metabolic dysregulation during diabetic ketoacidosis

Autor: Isabella Melena, Federica Piani, Kalie L. Tommerdahl, Cameron Severn, Linh T. Chung, Alexis MacDonald, Carissa Vinovskis, David Cherney, Laura Pyle, Carlos A. Roncal-Jimenez, Miguel A. Lanaspa, Arleta Rewers, Daniël H. van Raalte, Gabriel Cara-Fuentes, Chirag R. Parikh, Robert G. Nelson, Meda E. Pavkov, Kristen J. Nadeau, Richard J. Johnson, Petter Bjornstad

Publikováno v: Journal of Diabetes and its Complications, 36(6):108203. Elsevier Inc.
J Diabetes Complications
Melena, I, Piani, F, Tommerdahl, K L, Severn, C, Chung, L T, MacDonald, A, Vinovskis, C, Cherney, D, Pyle, L, Roncal-Jimenez, C A, Lanaspa, M A, Rewers, A, van Raalte, D H, Cara-Fuentes, G, Parikh, C R, Nelson, R G, Pavkov, M E, Nadeau, K J, Johnson, R J & Bjornstad, P 2022, ' Aminoaciduria and metabolic dysregulation during diabetic ketoacidosis : Results from the diabetic kidney alarm (DKA) study ', Journal of Diabetes and its Complications, vol. 36, no. 6, 108203 . https://doi.org/10.1016/j.jdiacomp.2022.108203

Objective: We examined changes in the excretion of various amino acids and in glycolysis and ketogenesis-related metabolites, during and after diabetic ketoacidosis (DKA) diagnosis, in youth with known or new onset type 1 diabetes (T1D). Methods: Uri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf1c3b238e73c2a80b7df98f037aacd
http://www.scopus.com/inward/record.url?scp=85129554744&partnerID=8YFLogxK

11-Oxygenated Androgen Metabolite Concentrations are Affected by Pubertal Progression and Obesity

Autor: Emily Breslow, Anya Taylor, Christine L. Chan, Cameron Severn, Laura Pyle, Laura Torchen, Ryan Sisk, Richard Legro, Adina F. Turcu, Richard J. Auchus, Andrea Duanaif, Megan Moriarty Kelsey, Melanie Cree-Green

Publikováno v: Hormone research in paediatrics.

Introduction: 11-oxygenated C19 steroids (11-oxyandrogens) have been shown to rise during adrenarche and remain higher throughout adulthood than in early childhood. The patterns of circulating 11-oxyandrogens throughout normal puberty has not yet bee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0956d2f28b9211f85e59b5cc2e871632
https://pubmed.ncbi.nlm.nih.gov/36446347