Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Cameron S Brandt"'
Autor:
Ruth Salmon, Eric M. Chadwick, Bailey Donahue, Melissa Chin, G. Grant Welstead, Clay Patton, Blythe D. Sather, Stephen Michael Burleigh, Dean Y. Toy, Brian J. Belmont, David Jeffrey Huss, Alexandra Croft, Stephen J. Goldfless, Cameron S. Brandt
Publikováno v:
Cancer Immunology Research. 7:A027-A027
Background: Adoptive T-cell therapy with engineered T-cell receptors (eTCR) has demonstrated promising, yet modest clinical benefit to date. Key obstacles for this technology are 1) competition with the endogenous TCR for CD3 components that are requ
Autor:
Wenfeng Xu, Eric Vivier, Christian Chabannon, Zeren Gao, Steven D. Levin, Craig D. Ostrander, Robert L. West, Tomonori Kaifu, Myriam Baratin, Cameron S. Brandt, Betty A. Haldeman, Brian A. Fox, Jacob J. Kennedy, Alessandro Moretta, Eugene C. Yi
Publikováno v:
The Journal of Experimental Medicine
Cancer development is often associated with the lack of specific and efficient recognition of tumor cells by the immune system. Natural killer (NK) cells are lymphocytes of the innate immune system that participate in the elimination of tumors. We re
Autor:
Donald C. Foster, Patricia A. Mckernan, Lena Yao, Stephen R. Jaspers, James West, Karen L. Madden, Ty Brender, Laura J. Jelinek, Wenfeng Xu, Cameron S. Brandt, Crystal Jones, Julia Parrish-Novak, Yasmin A. Chandrasekher
Publikováno v:
Journal of Biological Chemistry. 277:47517-47523
Cytokines that signal through Class II receptors form a distinct family that includes the interferons and interleukin 10 (IL-10). Recent identification of several IL-10 homologs has defined a cytokine subfamily that includes AK155, IL-19, IL-20, IL-2
Autor:
Don Foster, Mark D. Heipel, Theodore E. Whitmore, Stacey R. Dillon, Margaret D. Moore, Susan Bort, Jane A. Gross, Cindy A. Sprecher, Karen L. Madden, Philippa J. Webster, Fenella C. Raymond, Janet V. Johnston, Cameron S. Brandt, Andrew Nelson, Teresa Gilbert, Kevin Hambly, Mark F. Maurer, Darrell C. Conklin, Sara K. Schrader, Francis J. Grant, Rick D. Holly, Andrew Ching, Wenfeng Xu, Sherri Mudri, Kenneth Kaushansky, Faith Shiota, Scott R. Presnell, Lena Yao, Angie Hammond, Catherine Lofton-Day, Steve K. Burkhead, Julia Parrish-Novak, Chris Clegg, Joseph L. Kuijper, Jon Berry, Deborah L. Smith, Janet M. Kramer, James A. West
Publikováno v:
Nature. 408:57-63
Cytokines are important in the regulation of haematopoiesis and immune responses, and can influence lymphocyte development. Here we have identified a class I cytokine receptor that is selectively expressed in lymphoid tissues and is capable of signal
Autor:
Edward D. Howard, Ardourel Daniel F, Fred Ramsdell, Craig D. Ostrander, Janet V. Johnston, Katherine E. Lewis, LuAnn Hebb, Janine Bilsborough, James W. West, Kristen Bontadelli, Zeren Gao, Joseph L. Kuijper, Christoph Bucher, Eric M. Chadwick, Mark W. Rixon, Anitra Wolf, Steven D. Levin, Bruce R. Blazar, Thomas R. Bukowski, Cameron S. Brandt, Angela K. Hammond, Brian A. Fox, Wenfeng Xu, David W. Taft
Members of the CD28 family play important roles in regulating T cell functions and share a common gene structure profile. We have identified VSTM3 as a protein whose gene structure matches that of the other CD28 family members. This protein (also kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7614d95af9e079b1a87ae3169cc8051e
https://europepmc.org/articles/PMC3733993/
https://europepmc.org/articles/PMC3733993/
Publikováno v:
Molecular and Cellular Biology. 13:5348-5359
The c-fms gene encodes the receptor for the macrophage colony-stimulating factor (M-CSF), and its extracellular domain consists of five immunoglobulin-like subdomains. To identify which of the five immunoglobulin-like regions are involved in ligand b
Autor:
Okada Shannon L, Steven D. Levin, Jay K. Kolls, Craig D. Ostrander, Rolf E. Kuestner, Karen Lum, Ty Brender, Aaron C. Haran, David W. Taft, James L. Kreindler, Pamela Shea, Shean J. Aujla, Cameron S. Brandt, Thomas R. Bukowski, Julia Parrish-Novak, Jeff L. Ellsworth, Mark W. Rixon, Brian Reardon, Margaret D. Moore, Katherine E. Lewis, Mark W. Appleby, Zeren Gao, Brandon Harder, Stephen R. Jaspers, Randall W. Schreckhise, Scott R. Presnell, Patricia I. Guerra-Lewis, James W. West
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 179(8)
The proinflammatory cytokines IL-17A and IL-17F have a high degree of sequence similarity and share many biological properties. Both have been implicated as factors contributing to the progression of inflammatory and autoimmune diseases. Moreover, re
Publikováno v:
Molecular and cellular biology. 14(7)
The receptor (Fms) for macrophage colony-stimulating factor (M-CSF) is a member of the tyrosine kinase class of growth factor receptors. It maintains survival, stimulates growth, and drives differentiation of the macrophage lineage of hematopoietic c
Autor:
Steven D Levin, Cameron S Brandt, Eugene C Yi, Jacob Kennedy, Zeren Gao, Brian Fox, Betty Haldeman, Craig Ostrander, Robert West, Wenfeng Xu
Publikováno v:
The Journal of Immunology. 182:134.20-134.20
We have identified a common gene structure found in all known members of the CD28 family and have used this conserved structure to include the Natural Cytotoxicity Receptor NKp30 as a CD28 family member. Soluble forms of NKp30 specifically bound to t
Autor:
Steven D Levin, Cameron S Brandt, Edward D Howard, Janet Johnston, Eric Chadwick, Angela Hammond, David W Taft, Luanne Hebb, Anitra Wolf, Thomas R Bukowski, Mark Rixon, Craig D Ostrander, James W West, Brian Fox, Zeren Gao, Katherine Lewis, Wenfeng Xu, Fred Ramsdell
Publikováno v:
The Journal of Immunology. 182:90.31-90.31
Members of the B7-CD28 family play critical roles in the response of T cells. We have identified the transmembrane protein Vstm3 as a member of the CD28 family based on gene structure. It has two immunoreceptor tyrosine inhibitory motifs in its cytop