Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Cameron M. L. Clokie"'
Autor:
Peter N. Burns, Norbert Kartner, Hanje Chen, Cameron M L Clokie, Sean A.F. Peel, Nikita Reznik, Gazelle Crasto, Morris F. Manolson, Ross Williams, Michael V. Spatafora
Publikováno v:
Journal of Controlled Release. 243:99-108
Recombinant human bone morphogenetic protein 2 (rhBMP-2) is used clinically to enhance implant-mediated bone regeneration. However, there are risks associated with the high rhBMP-2 dose that is required in the implant to mitigate diffusional loss ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5cb813e11fc578566b52e2920a11066
https://doi.org/10.1016/j.jconrel.2016.09.032
https://doi.org/10.1016/j.jconrel.2016.09.032
Publikováno v:
Journal of Oral and Maxillofacial Surgery. 73:1095-1105
Purpose Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is a severe but extremely rare complication of prolonged treatment with bisphosphonates (BPs). Improper treatment or misdiagnosis can have serious repercussions. In some cases, the trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f15193b9ce9a013aeff1b716336dd70
https://doi.org/10.1016/j.joms.2014.12.040
https://doi.org/10.1016/j.joms.2014.12.040
Publikováno v:
Clinical Applications of Biomaterials ISBN: 9783319560588
Recombinant human bone morphogenetic protein (BMP) containing implants can be as effective as autogenous bone grafts and have been approved clinically to stimulate spine fusion, repair of long bone non-unions and bone augmentation in the jaw.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7555bbff5b67d263e906724aeaa80bed
https://doi.org/10.1007/978-3-319-56059-5_12
https://doi.org/10.1007/978-3-319-56059-5_12
Autor:
David Backstein, Cameron M L Clokie, David J. Psutka, Gerald I. Baker, David R. Walt, Howard C. Tenenbaum, Sean A.F. Peel, Jonathan B Albilia
Publikováno v:
Journal of Orthopaedic Research. 31:44-52
To date, there is no objective or reliable means of assessing the severity of degenerative joint disease (DJD) and need for joint replacement surgery. Hence, it is difficult to know when an individual with DJD has reached a point where total arthropl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::673443b3345fd87c75ef13fa9d4f08de
https://doi.org/10.1002/jor.22182
https://doi.org/10.1002/jor.22182
Publikováno v:
Growth Factors. 30:267-275
Proteolytic cleavage of precursor bone morphogenetic protein (proBMP) is an important step in generating the active mature BMP. ProBMP-2 contains two proprotein convertase (PC) recognition sites (S1 and S2) and is postulated to be cleaved by PCs at t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921043a996d658cbb050ec2c33c9714e
https://doi.org/10.3109/08977194.2012.686497
https://doi.org/10.3109/08977194.2012.686497
Publikováno v:
Biotechnology Letters. 34:221-230
To improve recombinant human bone morphogenetic protein-2 (rhBMP-2) yield, cell lines stably expressing hBMP2 were cultured in the presence of polyarginine peptide IND-1 and showed up to 6-fold increase in the yield of mature BMP-2. Repeated addition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81cfec9bca3ea0cfe1b773fb3e299563
https://doi.org/10.1007/s10529-011-0781-7
https://doi.org/10.1007/s10529-011-0781-7
Autor:
Leena P. Ylikontiola, Robert P. Carmichael, George K.B. Sándor, Ahmed Jan, Cameron M L Clokie, Marc G. Duval
Publikováno v:
Oral Wound Healing
Dentofacial defects can be small or very large, consisting of defects in the craniomaxillofacial region with missing soft tissue, bony and other hard tissue components. Such combined mucosal, osseous and even cartilaginous defects can be reconstructe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcc8c1e7bd699388a550bac0fb69f14f
https://doi.org/10.1111/etp.12017
https://doi.org/10.1111/etp.12017
Autor:
Sacha Dubois, Nazir Khan, Aliya Khan, Mohammed O. Rahman, Cameron M L Clokie, Lorena P. Rios, George K.B. Sándor, Edward Dore, Edmund Peters
Publikováno v:
The Journal of Rheumatology. 38:1396-1402
Objective.Osteonecrosis of the jaw (ONJ) in association with use of bisphosphonate (BP) has been described primarily in cancer patients receiving high-dose intravenous BP. The frequency of the condition in patients with osteoporosis appears to be low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5061efd68f9c5d5d15676833298ed29
https://doi.org/10.3899/jrheum.100221
https://doi.org/10.3899/jrheum.100221
Autor:
Dayne Miller, George K.B. Sándor, Cameron M L Clokie, Bruno Girard, David Wilson, Sean A.F. Peel, Martin Cloutier
Publikováno v:
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 110:720-728
Objective. This study compared the healing of 2 laser ablation units, erbium YAG and femtosecond lasers versus conventional mechanical cutting with carbide and diamond drills to explore future applications for bone surgery. The effects of laser or me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a1a24317525a506a8a91c5d8a19aa9
https://doi.org/10.1016/j.tripleo.2010.04.003
https://doi.org/10.1016/j.tripleo.2010.04.003
Publikováno v:
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 109:531-540
Objectives Recent research has focused on application of growth factors such as bone morphogenetic proteins (BMPs) as alternatives to autogenous bone grafting. Two bone graft substitute bioimplants containing recombinant human BMPs (rhBMPs), Infuse (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542e0ec41c13b3494b9ce6813bdf5946
https://doi.org/10.1016/j.tripleo.2009.10.027
https://doi.org/10.1016/j.tripleo.2009.10.027