Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Cameron M Scott"'
Autor:
Cameron M Scott, JiHoon Eric Joo, Neil O'Callaghan, Daniel D Buchanan, Mark Clendenning, Graham G Giles, John L Hopper, Ee Ming Wong, Melissa C Southey
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165436 (2016)
DNA methylation can mimic the effects of both germline and somatic mutations for cancer predisposition genes such as BRCA1 and p16INK4a. Constitutional DNA methylation of the BRCA1 promoter has been well described and is associated with an increased
Externí odkaz:
https://doaj.org/article/458030cf1f014da3b7ca4ece405e229e
Autor:
Andrew M. Scott, Cameron M. Scott, Analia Lesmana, Rebecca Nightingale, Lars Tögel, Holly Anderton, Irvin Ng, Suresh Mathivanan, Yann Gibert, Hina Kalra, Mercedes Dávalos-Salas, Paul Ioannidis, David S. Williams, Shivakumar Keerthikumar, Angela Rigopoulos, John M. Mariadason, Sylvia J. Gong, Kim S. Bell-Anderson, Camilla M. Reehorst, Sheren Al-Obaidi, Matthew J. Watt, Scott W. Hiebert, Prusoth Yoganantharaja, Magdalene K. Montgomery
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Histone deacetylase 3 (Hdac3) regulates the expression of lipid metabolism genes in multiple tissues, however its role in regulating lipid metabolism in the intestinal epithelium is unknown. Here we demonstrate that intestine-specific deletion of Hda
Autor:
Wiphawan Wasenang, Amardeep S. Dhillon, Yvonne Yeung, Temduang Limpaiboon, Dmitri Mouradov, Oliver M. Sieber, Daniel Croagh, Ian Y. Luk, Laura J. Jenkins, Niall C. Tebbutt, George F. Iatropoulos, Toshihide Muramatsu, Camilla M. Reehorst, Andrew Weickhardt, Cameron M. Scott, David K. Lau, Yoshimasa Saito, John M. Mariadason, Mehrdad Nikfarjam, David S. Williams, Fiona Chionh
Publikováno v:
iScience
iScience, Vol 21, Iss, Pp 624-637 (2019)
iScience, Vol 21, Iss, Pp 624-637 (2019)
Summary Biliary tract cancers (BTCs) currently have no approved targeted therapies. Although genomic profiling of primary BTCs has identified multiple potential drug targets, accurate models are needed for their evaluation. Genomic profiling of 22 BT
Autor:
Melissa C. Southey, Ee Ming Wong, Neil O'Callaghan, John L. Hopper, Chol-Hee Jung, Jihoon E. Joo, Cameron M. Scott, Graham G. Giles, James G. Dowty, Pierre Antoine Dugué
Publikováno v:
Experimental and molecular pathology. 105(3)
Breast cancers arising in women carrying a germline mutation in BRCA1 are typically high-grade, early-onset and have distinct morphological features (BRCA1-like). However, the majority of early-onset breast cancers of this morphological type are not
Autor:
Mark Clendenning, Neil O'Callaghan, Melissa C. Southey, Cameron M. Scott, Graham G. Giles, Jihoon E. Joo, Daniel D. Buchanan, John L. Hopper, Ee Ming Wong
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 11, p e0165436 (2016)
PLoS ONE, Vol 11, Iss 11, p e0165436 (2016)
DNA methylation can mimic the effects of both germline and somatic mutations for cancer predisposition genes such as BRCA1 and p16INK4a. Constitutional DNA methylation of the BRCA1 promoter has been well described and is associated with an increased
Autor:
Mercedes Dávalos-Salas, Magdalene K. Montgomery, Camilla M. Reehorst, Rebecca Nightingale, Irvin Ng, Holly Anderton, Sheren Al-Obaidi, Analia Lesmana, Cameron M. Scott, Paul Ioannidis, Hina Kalra, Shivakumar Keerthikumar, Lars Tögel, Angela Rigopoulos, Sylvia J. Gong, David S. Williams, Prusoth Yoganantharaja, Kim Bell-Anderson, Suresh Mathivanan, Yann Gibert, Scott Hiebert, Andrew M. Scott, Matthew J. Watt, John M. Mariadason
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Histone deacetylase 3 (HDAC3) is a regulator of lipid homeostasis in several tissues, however, its role in intestinal lipid metabolism was not yet known. Here the authors study intestine specific HDAC3 knock out mice and report that these animals hav
Externí odkaz:
https://doaj.org/article/517f7ab37ce74aff9258c9ede119de9a
Autor:
David K. Lau, Dmitri Mouradov, Wiphawan Wasenang, Ian Y. Luk, Cameron M. Scott, David S. Williams, Yvonne H. Yeung, Temduang Limpaiboon, George F. Iatropoulos, Laura J. Jenkins, Camilla M. Reehorst, Fiona Chionh, Mehrdad Nikfarjam, Daniel Croagh, Amardeep S. Dhillon, Andrew J. Weickhardt, Toshihide Muramatsu, Yoshimasa Saito, Niall C. Tebbutt, Oliver M. Sieber, John M. Mariadason
Publikováno v:
iScience, Vol 21, Iss , Pp 624-637 (2019)
Summary: Biliary tract cancers (BTCs) currently have no approved targeted therapies. Although genomic profiling of primary BTCs has identified multiple potential drug targets, accurate models are needed for their evaluation. Genomic profiling of 22 B
Externí odkaz:
https://doaj.org/article/60855650f6624ff1817442e9b3685ec7