Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Cameron Lenahan"'
Autor:
Yu Tian, Lu Han, Cameron Lenahan, Tao Wang, Tian Tian, Rui Liu, Lijuan Liu, Jian Huang, Lu Wang, Xiao Hu
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e26659- (2024)
Background: The coexistence of autoimmune encephalitis (AE) with multiple neural auto-antibodies is of great clinical significance because overlying antibodies may cause superposition or variation of clinical syndrome, which increases the difficulty
Externí odkaz:
https://doaj.org/article/b9bd4fcf21b04a8b87f333030bf3394f
Autor:
Wenhui Tang, Ningbo Xu, Jian Zhou, Zhenyan He, Cameron Lenahan, Chenyang Wang, Huangyi Ji, Boyang Liu, Yujiao Zou, Huijun Zeng, Hongbo Guo
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-13 (2022)
Abstract N6-methylation of adenosine (m6A) is one of the most frequent chemical modifications in eukaryotic RNAs and plays a vital role in tumorigenesis and progression. Recently, emerging studies have shown that m6A modification by ALKBH5 was associ
Externí odkaz:
https://doaj.org/article/efcc1ba016cd4a049b862a25d1a80150
Autor:
Peng Jin, Dongqing Qi, Yuhui Cui, Cameron Lenahan, John H. Zhang, Xiaogen Tao, Shuixiang Deng, Jiping Tang
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Background Pyroptosis is a programmed cell death mediated by inflammasomes. Previous studies have reported that inhibition of neurokinin receptor 1 (NK1R) exerted neuroprotection in several neurological diseases. Herein, we have investigated
Externí odkaz:
https://doaj.org/article/7fc955ddb0b7445a9c0f207d152c58b7
Autor:
Jun Yan, Weilin Xu, Cameron Lenahan, Lei Huang, Umut Ocak, Jing Wen, Gaigai Li, Wei He, Chensheng Le, John H. Zhang, Ligen Mo, Jiping Tang
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-17 (2022)
Abstract Background C–C chemokine receptor type 1 (CCR1) and its endogenous ligand, CCL5, participate in the pathogenesis of neuroinflammatory diseases. However, much remains unknown regarding CCL5/CCR1 signaling in blood–brain barrier (BBB) perm
Externí odkaz:
https://doaj.org/article/f179effe51ad46f98ff5721a8af8f51a
Autor:
Kaijing Fu, Weilin Xu, Cameron Lenahan, Yong Mo, Jing Wen, Teng Deng, Qianrong Huang, Fangzhou Guo, Ligen Mo, Jun Yan
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2023)
Intracerebral hemorrhage (ICH) is the second-largest stroke subtype and has a high mortality and disability rate. Secondary brain injury (SBI) is delayed after ICH. The main contributors to SBI are inflammation, oxidative stress, and excitotoxicity.
Externí odkaz:
https://doaj.org/article/e73b9fda9ee74a13a422915828d84113
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Subarachnoid hemorrhage (SAH) is an important public health concern with high morbidity and mortality worldwide. SAH induces cell death, blood−brain barrier (BBB) damage, brain edema and oxidative stress. As the most abundant cell type in the centr
Externí odkaz:
https://doaj.org/article/ec5ecc89bfb642ed9198ff97835f3617
Autor:
Ningbo Xu, Xifeng Li, Jun Weng, Chunhua Wei, Zhenyan He, Desislava Met Doycheva, Cameron Lenahan, Wenhui Tang, Jian Zhou, Yanchao Liu, Qiang Xu, Yahong Liu, Xuying He, Jiping Tang, John H. Zhang, Chuanzhi Duan
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Adiponectin (APN), a fat-derived plasma hormone, is a classic anti-inflammatory agent. Multiple studies have demonstrated the beneficial role of APN in acute brain injury, but the effect of APN in germinal matrix hemorrhage (GMH) is unclear, and the
Externí odkaz:
https://doaj.org/article/b1233ba1c91543cfb90e53d879fe9062
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The ketogenic diet (KD) is a low-carbohydrate, high-fat diet regarded as a potential intervention for cancers owing to its effects on tumor metabolism and behavior. Hepatocellular carcinoma (HCC) is the most prevalent type of liver cancer, and its ma
Externí odkaz:
https://doaj.org/article/6aeb4641303a44b18e1e5fb97b4b78bd
Publikováno v:
BMC Neuroscience, Vol 22, Iss 1, Pp 1-14 (2021)
Abstract Background Rupture of intracranial aneurysm (IA) is the main cause of devastating subarachnoid hemorrhage, which urges our understanding of the pathogenesis and regulatory mechanisms of IA. However, the regulatory roles of long non-coding RN
Externí odkaz:
https://doaj.org/article/a3f98a8bcdc8461fb799d8b67c07f4f7
Autor:
Shufeng Yu, Desislava Met Doycheva, Marcin Gamdzyk, Yijun Yang, Cameron Lenahan, Gaigai Li, Dujuan Li, Lifei Lian, Jiping Tang, Jun Lu, John H. Zhang
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-20 (2021)
Abstract Background Microglia-mediated neuroinflammation plays a crucial role in the pathogenesis of hypoxic-ischemic (HI)-induced brain injury. Activation of melanocortin-1 receptor (MC1R) has been shown to exert anti-inflammatory and neuroprotectiv
Externí odkaz:
https://doaj.org/article/b354140e710d4c65a6093bda7180e996