Systemic Pseudohypoaldosteronism Type I: A Case Report and Review of the Literature

Autor: Nasifa Nur, Cameron Lang, Juanita K. Hodax, Jose Bernardo Quintos

Publikováno v: Case Reports in Pediatrics, Vol 2017 (2017)

Systemic pseudohypoaldosteronism (PHA) type I is a rare genetic disorder resulting from mutations in the subunits of the epithelial sodium channel that manifests as severe salt wasting, hyperkalemia, and metabolic acidosis in infancy. In this article

Externí odkaz: https://doaj.org/article/2d38fba78ac84b029b662b6f6a652979

Chimeric antigen receptor‐modified human regulatory T cells that constitutively express IL‐10 maintain their phenotype and are potently suppressive

Autor: Yasmin R. Mohseni, Amy Cross, Gilbert O. Fruhwirth, Qi Peng, Sim L. Tung, Robert I. Lechler, Cameron Lang, Cristiano Scottà, Joanna Hester, George Adigbli, Fadi Issa, Alessia Volpe, Caroline Dudreuilh, Farzin Farzaneh, Giovanna Lombardi, Adeel Saleem

Publikováno v: European Journal of Immunology

Clinical trials of Treg therapy in transplantation are currently entering phases IIa and IIb, with the majority of these employing polyclonal Treg populations that harbor a broad specificity. Enhancing Treg specificity is possible with the use of chi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df419825fa2dfa2c55c75e210bd72484
https://doi.org/10.1002/eji.202048934

Spatiotemporal PET Imaging Reveals Differences in CAR-T Tumor Retention in Triple-Negative Breast Cancer Models

Autor: Candice Ashmore-Harris, Ewelina Kurtys, Preeth Johnson, Lindsay Lim, Rafael Torres Martin de Rosales, Elena Skourti, Alessia Volpe, Cameron Lang, Francis Man, Gilbert O. Fruhwirth

Publikováno v: Molecular Therapy
Volpe, A, Lang, C, Lim, L, Man, F, Kurtys, E, Ashmore-Harris, C, Johnson, P, Skourti, E, T. M. de Rosales, R & Fruhwirth, G 2020, ' Spatiotemporal PET Imaging Reveals Differences in CAR-T Tumor Retention in Triple-Negative Breast Cancer Models ', Molecular therapy : the journal of the American Society of Gene Therapy, vol. 28, no. 10, pp. 2271-2285 . https://doi.org/10.1016/j.ymthe.2020.06.028

Chimeric antigen receptor T cell therapy (CAR-T) has been rolled out as a new treatment for hematological malignancies. For solid tumor treatment, CAR-T has been disappointing so far. Challenges include the quantification of CAR-T trafficking, expans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5caee0eec66caa4564603f474d64075
https://pubmed.ncbi.nlm.nih.gov/32645298

Illustrations of integrand-basis building at two loops

Autor: Jacob L. Bourjaily, Cameron Langer, Yaqi Zhang

Publikováno v: Journal of High Energy Physics, Vol 2022, Iss 8, Pp 1-36 (2022)

Abstract We outline the concrete steps involved in building prescriptive master integrand bases for scattering amplitudes beyond the planar limit. We highlight the role of contour choices in such bases, and illustrate the full process by constructing

Externí odkaz: https://doaj.org/article/23bead204b7c4a40bfcd8913b8a181c3

Locally-finite quantities in sYM

Autor: Jacob L. Bourjaily, Cameron Langer, Kokkimidis Patatoukos

Publikováno v: Journal of High Energy Physics, Vol 2021, Iss 4, Pp 1-21 (2021)

Abstract A locally-finite quantity is one for which there is no region of divergence anywhere in the space of real loop momenta; it can therefore be computed (in principle) without regularization. In this work, we prove that all two-loop ratio functi

Externí odkaz: https://doaj.org/article/f9e6a044f1e44e3097c6c830a751676a