Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Cameron K Postnikoff"'
Autor:
Cameron K Postnikoff, Robert Pintwala, Sara Williams, Ann M Wright, Denise Hileeto, Maud B Gorbet
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96448 (2014)
PURPOSE: To further improve in vitro models of the cornea, this study focused on the creation of a three-dimensional, stratified, curved epithelium; and the subsequent characterization and evaluation of its suitability as a model for biocompatibility
Externí odkaz:
https://doaj.org/article/b10cca59a8094a068b5f93783ac3c418
Publikováno v:
Current Eye Research. 47:1479-1487
miRNAs can regulate inflammatory pathways. The purpose of this work was to determine if inflammatory-related tear film miRNAs are associated with extracellular vesicles (EVs) in human non-Sjögren's Syndrome dry eye disease (DED) participants.Five DE
Autor:
Gabriel Rezonzew, Charitharth Vivek Lal, Amelia Freeman, Kelly K. Nichols, Cameron K Postnikoff, Amit Gaggar, Kent A. Willis
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Dry eye affects millions of individuals. In experimental models, dry eye disease is associated with T helper cell 17-mediated inflammation of the ocular surface that may cause persistent damage to the corneal epithelium. However, the initiating and p
Publikováno v:
The ocular surface. 18(4)
Purpose Closed eye neutrophils have demonstrated increased prevalence in dry eye disease, but the phenotype and extent of activation of these cells has yet to be described. Methods 12 normal subjects and 12 subjects with dry eye disease were recruite
Autor:
Amit Gaggar, Charitharth Vivek Lal, Kelly K. Nichols, Gabriel Rezonzew, Kent A. Willis, Cameron K Postnikoff, Amelia Freeman
Dry eye affects millions of individuals. In experimental models, dry eye disease is associated with T helper cell 17-mediated inflammation of the ocular surface that may cause persistent damage to the corneal epithelium. However, the initiating and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70c45b94a5985e36481a260c32a0064
The eye is a complex biological system, composed of different cell types, irrigated by several physiological solutions, subject to various mechanical stresses and which environment can also be affected by diurnal variations. As a biomaterial is place
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1d90f894c32e5aee1168876914a418b
https://doi.org/10.1016/b978-0-08-102967-1.00031-1
https://doi.org/10.1016/b978-0-08-102967-1.00031-1
Autor:
Cameron K Postnikoff, Kelly K. Nichols
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose This study sought to examine the changes and phenotype of the tear neutrophil and T-cell populations between early eyelid closure and after a full night of sleep. Methods Fourteen healthy participants were recruited and trained to wash the oc
Autor:
Maud Gorbet, Cameron K Postnikoff
Publikováno v:
Ocular immunology and inflammation. 26(5)
Purpose: Eyelid closure results in influx of neutrophils onto the ocular surface, which are non-responsive to inflammatory stimuli. This investigation examined whether incubation of blood-isolated neutrophils in closed-eye conditions induce a tear-fi
Publikováno v:
Journal of Biomaterials Applications. 29:1119-1132
Cataracts are the leading cause of blindness worldwide, requiring surgical implantation of an intraocular lens. Despite evidence of leukocyte ingress into the postoperative lens, few studies have investigated the leukocyte response to intraocular len
Publikováno v:
Annals of Biomedical Engineering. 42:1923-1931
Understanding the cellular and molecular mechanisms of the corneal tissue and translating them into effective therapies requires organotypic culture systems that can better model the physiological conditions of the front of the eye. Human corneal in