Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Cameron J, Brown"'
Autor:
Stephanie Yerdelen, Yihui Yang, Justin L. Quon, Charles D. Papageorgiou, Chris Mitchell, Ian Houson, Jan Sefcik, Joop H. ter Horst, Alastair J Florence, Cameron J. Brown
Publikováno v:
Crystal Growth & Design. 23:681-693
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::932fc3780c97c3c6baa29e3edc0ede62
https://doi.org/10.1021/acs.cgd.2c00192
https://doi.org/10.1021/acs.cgd.2c00192
Autor:
Matthew R. Wilkinson, Laura Pereira Diaz, Antony D. Vassileiou, John A. Armstrong, Cameron J. Brown, Bernardo Castro-Dominguez, Alastair J. Florence
Publikováno v:
Digital Discovery. 2:459-470
We present deep learning to predict the flowability of pharmaceuticals from microscopy images. This enables flowability assessments with smaller API quantities, saving experiment time and costs when material is limited during early drug development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62f34586f8ea165ee01400bda4428429
https://doi.org/10.1039/d2dd00123c
https://doi.org/10.1039/d2dd00123c
Publikováno v:
Crystal Growth & Design. 22:2105-2116
Small-scale crystallization experiments (1-8 mL) are widely used during early-stage crystallization process development to obtain initial information on solubility, metastable zone width, as well as attainable nucleation and/or growth kinetics in a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06604fc8120d84524f29225fe0e8eeaf
https://doi.org/10.1021/acs.cgd.1c01118
https://doi.org/10.1021/acs.cgd.1c01118
Autor:
John McGinty, Magdalene W. S. Chong, Andrew Manson, Cameron J. Brown, Alison Nordon, Jan Sefcik
Publikováno v:
Crystals, Vol 10, Iss 10, p 925 (2020)
Lovastatin crystals often exhibit an undesirable needle-like morphology. Several studies have shown how a needle-like morphology can be modified in antisolvent crystallisation with the use of additives, but there is much less experimental work demons
Externí odkaz:
https://doaj.org/article/32ca1bff9f8844b785b3ecad9dece488
Autor:
Diego A. Maldonado, Antony Vassileiou, Blair Johnston, Alastair J. Florence, Cameron J. Brown
The population balance model is a valuable modelling tool which facilitates the optimization and understanding of crystallization processes. However, in order to use this tool, it is necessary to have previous knowledge of the crystallization kinetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ef4055e0dd07e3a98f1291d7cc3d41
https://strathprints.strath.ac.uk/82313/1/Maldonado_etal_DD_2022_Data_mining_crystallization_kinetics.pdf
https://strathprints.strath.ac.uk/82313/1/Maldonado_etal_DD_2022_Data_mining_crystallization_kinetics.pdf
Autor:
Magdalene W. S. Chong, Thomas McGlone, Ching Yee Chai, Naomi E. B. Briggs, Cameron J. Brown, Francesca Perciballi, Jaclyn Dunn, Andrew J. Parrott, Paul Dallin, John Andrews, Alison Nordon, Alastair J. Florence
Publikováno v:
Organic process researchdevelopment. 26(11)
Changes in temperature can significantly affect spectroscopic-based methods for in situ monitoring of processes. As varying temperature is inherent to many processes, associated temperature effects on spectra are unavoidable, which can hinder solute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9792ee560c770d954e0c470d4e946325
https://pubmed.ncbi.nlm.nih.gov/36437900
https://pubmed.ncbi.nlm.nih.gov/36437900
Autor:
Murray N. Robertson, Blair F. Johnston, Bruce Wareham, Cameron J. Brown, Sara Ottoboni, Chris John Price, Antony D. Vassileiou
Publikováno v:
Organic Process Research & Development
A predictive tool was developed to aid process design and to rationally select optimal solvents for isolation of active pharmaceutical ingredients. The objective was to minimize the experimental work required to design a purification process by (i) s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98afc1418af854a566bbaaad030b2e13
https://doi.org/10.1021/acs.oprd.0c00532
https://doi.org/10.1021/acs.oprd.0c00532
Autor:
Sara Ottoboni, Cameron J. Brown, Bhavik Mehta, Guillermo Jimeno, Niall A. Mitchell, Jan Sefcik, Chris J. Price
Publikováno v:
Organic process researchdevelopment. 26(12)
To facilitate integrated end-to-end pharmaceutical manufacturing using digital design, a model capable of transferring material property information between operations to predict product attributes in integrated purification processes has been develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a722a242365e698102e1a334f98cfb
https://pubmed.ncbi.nlm.nih.gov/36569418
https://pubmed.ncbi.nlm.nih.gov/36569418
Autor:
Alison Nordon, John McGinty, Cameron J. Brown, Andrew Manson, Magdalene W. S. Chong, Jan Sefcik
Publikováno v:
Crystals, Vol 10, Iss 925, p 925 (2020)
Crystals
Volume 10
Issue 10
Crystals
Volume 10
Issue 10
Lovastatin crystals often exhibit an undesirable needle-like morphology. Several studies have shown how a needle-like morphology can be modified in antisolvent crystallisation with the use of additives, but there is much less experimental work demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::484def56e7584d6a75c48a7133e61ed4
https://strathprints.strath.ac.uk/74209/1/McGinty_etal_Crystals_2020_Effect_of_process_conditions_on_particle_size_and_shape.pdf
https://strathprints.strath.ac.uk/74209/1/McGinty_etal_Crystals_2020_Effect_of_process_conditions_on_particle_size_and_shape.pdf
Autor:
Aaron M. Fairbanks, Maria-Cristina Moldovan-Loomis, Leon F. Garcia-Martinez, Pieter Poolman, Jayme S Waite, Levi P. Sowers, Cameron J Brown, Bennett R Robertson, Andrew F. Russo, William C Castonguay, Bianca N. Mason, Chantel M Schmidt, Johannes Ledolter, Anne-Sophie Wattiez, Randy H. Kardon, Brandon J. Rea
Publikováno v:
Pain. 159:2306-2317
Migraine is the third most common disease in the world (behind dental caries and tension-type headache) with an estimated global prevalence of 15%, yet its etiology remains poorly understood. Recent clinical trials have heralded the potential of ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bbf3ccfd4cc25f1765b0047ce55f351
https://doi.org/10.1097/j.pain.0000000000001337
https://doi.org/10.1097/j.pain.0000000000001337