Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Cameron Dezfulian"'
Autor:
Patrick J. Coppler, David J. Gagnon, Katharyn L. Flickinger, Jonathan Elmer, Clifton W. Callaway, Francis X. Guyette, Ankur Doshi, Alexis Steinberg, Cameron Dezfulian, Ari L. Moskowitz, Michael Donnino, Teresa L. May, David B. Seder, Jon C. Rittenberger
Publikováno v:
Clinical and Experimental Emergency Medicine, Vol 11, Iss 2, Pp 205-212 (2024)
Objective We hypothesized that the administration of amantadine would increase awakening of comatose patients resuscitated from cardiac arrest. Methods We performed a prospective, randomized, controlled pilot trial, randomizing subjects to amantadine
Externí odkaz:
https://doaj.org/article/167fa17356a04a76bb9d4eb2aa7cad80
Autor:
Travis C. Jackson, Cameron Dezfulian, Vincent A. Vagni, Jason Stezoski, Keri Janesko-Feldman, Patrick M. Kochanek
Publikováno v:
Biomolecules, Vol 12, Iss 10, p 1352 (2022)
Pleckstrin homology domain and leucine rich repeat protein phosphatase (PHLPP) knockout mice have improved outcomes after a stroke, traumatic brain injury (TBI), and decreased maladaptive vascular remodeling following vascular injury. Thus, small-mol
Externí odkaz:
https://doaj.org/article/94f79b484c8b480abdbdce6149230bfd
Autor:
Thomas Uray, Cameron Dezfulian, Abigail A. Palmer, Kristin M. Miner, Rehana K. Leak, Jason P. Stezoski, Keri Janesko‐Feldman, Patrick M. Kochanek, Tomas Drabek
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 5 (2021)
Background Current postresuscitative care after cardiac arrest (CA) does not address the cause of CA. We previously reported that asphyxial CA (ACA) and ventricular fibrillation CA (VFCA) elicit unique injury signatures. We hypothesized that the earl
Externí odkaz:
https://doaj.org/article/d62d95d93cc243bfa7def83aa2a0f282
Autor:
Dario A. Vitturi, Charles Maynard, Michele Olsufka, Adam C. Straub, Nick Krehel, Peter J. Kudenchuk, Graham Nichol, Michael Sayre, Francis Kim, Cameron Dezfulian
Publikováno v:
Redox Biology, Vol 32, Iss , Pp - (2020)
Brain and heart injury cause most out-of-hospital cardiac arrest deaths but limited pharmacotherapy exists to protect these tissues. Nitrite is a nitric oxide precursor that is protective in pre-clinical models of ischemic injury and safe in Phase I
Externí odkaz:
https://doaj.org/article/01583875712d470e9233c696abea8243
Autor:
Cody A Rutledge, Takuto Chiba, Kevin Redding, Cameron Dezfulian, Sunder Sims-Lucas, Brett A Kaufman
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0237292 (2020)
AimMouse models of sudden cardiac arrest are limited by challenges with surgical technique and obtaining reliable venous access. To overcome this limitation, we sought to develop a simplified method in the mouse that uses ultrasound-guided injection
Externí odkaz:
https://doaj.org/article/ff04b416d3644a6fb335cdf2730f0b98
Autor:
Cameron Dezfulian, Maia Taft, Catherine Corey, Gabrielle Hill, Nicholas Krehel, Jon C. Rittenberger, Frank X. Guyette, Sruti Shiva
Publikováno v:
Redox Biology, Vol 12, Iss , Pp 491-498 (2017)
Remote Ischemic Conditioning (RIC), induced by brief cycles of ischemia and reperfusion, protects vital organs from a prolonged ischemic insult. While several biochemical mediators have been implicated in RIC's mechanism of action, it remains unclear
Externí odkaz:
https://doaj.org/article/11ea2d714ca04bf6bae4a04677a1529f
The benefits of youth are lost on the young cardiac arrest patient [version 1; referees: 2 approved]
Publikováno v:
F1000Research, Vol 6 (2017)
Children and young adults tend to have reduced mortality and disability after acquired brain injuries such as trauma or stroke and across other disease processes seen in critical care medicine. However, after out-of-hospital cardiac arrest (OHCA), ou
Externí odkaz:
https://doaj.org/article/a01330cadb844762b158ca323452cfb2
Autor:
Andrew M. Lamade, Tamil S. Anthonymuthu, Elizabeth M. Kenny, Hitesh Gidwani, Nicholas M. Krehel, Andrew A. Amoscato, Adam C. Straub, Valerian E. Kagan, Cameron Dezfulian, Hülya Bayır
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 17-17 (2018)
OBJECTIVES/SPECIFIC AIMS: Neurological injury remains as the main limiting factor for overall recovery after cardiac arrest (CA). Currently available indicators of neurological injury are inadequate for early prognostication after return of spontaneo
Externí odkaz:
https://doaj.org/article/18461b9ed5e34375af3e4a57de3ab794
Publikováno v:
Respiratory Medicine Case Reports, Vol 15, Iss C, Pp 7-8 (2015)
Massive pulmonary hemorrhage can pose a significant therapeutic challenge. Traditional methods of airway clearance using saline lavage and direct thrombus removal via bronchoscopy have limited ability to retrieve thrombi from deep airways. We report
Externí odkaz:
https://doaj.org/article/c5ea125d95ca428cae932ee1eff50d74
Autor:
Kunjan R Dave, Sanjoy K Bhattacharya, Isabel Saul, R Anthony DeFazio, Cameron Dezfulian, Hung Wen Lin, Ami P Raval, Miguel A Perez-Pinzon
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22057 (2011)
The release of cytochrome c from the mitochondria following cerebral ischemia is a key event leading to cell death. The goal of the present study was to determine the mechanisms involved in post-ischemic activation of protein kinase c delta (δPKC) t
Externí odkaz:
https://doaj.org/article/355f6fc96e504e0781c95a774052e861