Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Cameron D Pernia"'
Autor:
Steven J. Granger, Victor May, Sayamwong E. Hammack, Eylül Akman, Sydney A. Jobson, Elizabeth A. Olson, Cameron D. Pernia, Nikos P. Daskalakis, Caitlin Ravichandran, William A. Carlezon, Kerry J. Ressler, Scott L. Rauch, Isabelle M. Rosso
Publikováno v:
European Journal of Psychotraumatology, Vol 15, Iss 1 (2024)
ABSTRACTIntroduction: Pituitary adenylate cyclase-activating polypeptide (PACAP) regulates plasticity in brain systems underlying arousal and memory and is associated with posttraumatic stress disorder (PTSD). Research in animal models suggests that
Externí odkaz:
https://doaj.org/article/0310fd5d6f434b3ea710bf48d02bfeb8
Autor:
Katherine Bassil, Anthi C. Krontira, Thomas Leroy, Alana I.H. Escoto, Clara Snijders, Cameron D. Pernia, R. Jeroen Pasterkamp, Laurence de Nijs, Daniel van den Hove, Gunter Kenis, Marco P. Boks, Krishna Vadodaria, Nikolaos P. Daskalakis, Elisabeth B. Binder, Bart P.F. Rutten
Publikováno v:
Neurobiology of Stress, Vol 23, Iss , Pp 100530- (2023)
Hypothalamic-pituitary adrenal (HPA)axis dysregulation has long been implicated in stress-related disorders such as major depression and post-traumatic stress disorder. Glucocorticoids (GCs) are released from the adrenal glands as a result of HPA-axi
Externí odkaz:
https://doaj.org/article/4a6b05cc3b3242c0859374839792ad82
Autor:
Wen-Ning Zhao, Brian T. D. Tobe, Namrata D. Udeshi, Lucius L. Xuan, Cameron D. Pernia, Daniel P. Zolg, Amanda J. Roberts, Deepak Mani, Sarah R. Blumenthal, Iren Kurtser, Debasis Patnaik, Irina Gaisina, Joshua Bishop, Steven D. Sheridan, Jasmin Lalonde, Steven A. Carr, Evan Y. Snyder, Stephen J. Haggarty
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-18 (2020)
Abstract The effective treatment of bipolar disorder (BD) represents a significant unmet medical need. Although lithium remains a mainstay of treatment for BD, limited knowledge regarding how it modulates affective behavior has proven an obstacle to
Externí odkaz:
https://doaj.org/article/3adcd41d1c9642cb98771f72e34b370f
Autor:
Kevin J. Clancy, Quentin Devignes, Poornima Kumar, Victor May, Sayamwong E. Hammack, Eylül Akman, Emily J. Casteen, Cameron D. Pernia, Sydney A. Jobson, Michael W. Lewis, Nikolaos P. Daskalakis, William A. Carlezon, Kerry J. Ressler, Scott L. Rauch, Isabelle M. Rosso
Publikováno v:
Neuropsychopharmacology.
The pituitary adenylate cyclase-activating polypeptide (PACAP) system is implicated in posttraumatic stress disorder (PTSD) and related amygdala-mediated arousal and threat reactivity. PTSD is characterized by increased amygdala reactivity to threat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5bb2048b9862c4e57ac01028987848c
https://doi.org/10.1038/s41386-023-01593-5
https://doi.org/10.1038/s41386-023-01593-5
Autor:
Lisette M. Acevedo, Jeffrey N. Lindquist, Breda M. Walsh, Peik Sia, Flavio Cimadamore, Connie Chen, Martin Denzel, Cameron D. Pernia, Barbara Ranscht, Alexey Terskikh, Evan Y. Snyder, David A. Cheresh
Publikováno v:
Stem Cell Reports, Vol 4, Iss 6, Pp 1075-1088 (2015)
To gain insight into the cellular and molecular cues that promote neurovascular co-patterning at the earliest stages of human embryogenesis, we developed a human embryonic stem cell model to mimic the developing epiblast. Contact of ectoderm-derived
Externí odkaz:
https://doaj.org/article/06246247775f42d7b312dc2b3d07c835
Autor:
Joseph T. Coyle, Richard L. Sidman, Brian T. D. Tobe, Aoi Jitsuki-Takahashi, Hiroko Makihara, Fumio Nakamura, Haruko Nakamura, Yoshio Hirayasu, Keisuke Watanabe, Naoya Yamashita, Glenn T. Konopaske, Evan Y. Snyder, Cameron D Pernia, Yoshio Goshima, Munetaka Nomoto, Reina Aoki, Yusuke Saigusa, Toshihiko Baba, Francine M. Benes, Mari Saito
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance There are no biomarkers for schizophrenia (SCZ), a disorder of dysfunctional neural networks. We demonstrate that a master regulator of cytoskeleton (“CRMP2”) and, hence, neural circuitry, may form the basis for such a biomarker beca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a9bb79a052ee84bd9c78fb40d942ed
http://europepmc.org/articles/PMC8346854
http://europepmc.org/articles/PMC8346854
Autor:
Deepak Mani, Cameron D. Pernia, Steven D. Sheridan, Jasmin Lalonde, Joshua A. Bishop, Brian T. D. Tobe, Debasis Patnaik, Namrata D. Udeshi, Stephen J. Haggarty, Steven A. Carr, Lucius L Xuan, Irina N. Gaisina, Evan Y. Snyder, Sarah R. Blumenthal, Daniel P Zolg, Wen-Ning Zhao, Amanda J. Roberts, Iren Kurtser
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-18 (2020)
Translational Psychiatry
Translational Psychiatry
The effective treatment of bipolar disorder (BD) represents a significant unmet medical need. Although lithium remains a mainstay of treatment for BD, limited knowledge regarding how it modulates affective behavior has proven an obstacle to discoveri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d09891b9b55d8c4fe273563331e97d
https://doi.org/10.1038/s41398-020-0753-6
https://doi.org/10.1038/s41398-020-0753-6
Autor:
Stephen J. Haggarty, Brian T. D. Tobe, Yoshio Goshima, Cameron D. Pernia, Evan Y. Snyder, Neal H. Nathan, Richard L. Sidman
Throughout much of human and medical history the brain has been a black box opaque to scientific investigation for a myriad of reasons ranging from societal to logistical barriers. Compounding this opacity, the biological effects of ecologically sour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92c4a24ffc6d2a90fffe7b9b7f544f05
https://doi.org/10.1016/b978-0-12-812034-7.00017-0
https://doi.org/10.1016/b978-0-12-812034-7.00017-0
Autor:
Julie G. Allickson, Rafael G. Amado, Usman Azam, Frank Barry, Irene Aldecoa Bilbao, Gwendolyn K. Binder, Justin L. Black, Karin Blumer, Eugene P. Brandon, David A. Brindley, William Murray Burns, Francesca Capone, Guillaume Carmona, Michael Chaffman, William Chou, Zhanfeng Cui, Kevin A. D’Amour, Nathan J. Dowden, Bernd Eschgfaeller, Eric Faulkner, Maria Cristina Galli, Yoshio Goshima, Stephen J. Haggarty, Celine-Lea Halioua-Haubold, Kristen Harrington-Smith, Darren Hickerson, William Ho, Johan Hyllner, Natasha Iyer, Marieke Jansen, Etienne Jousseaume, Sven Kili, Antoinette F. Konski, Lawrence S. Lamb, Ching Lam, Jaeseung Lim, Chi Lo, Thomas Malcolm, Almudena Martinez-Fernandez, Todd Meinecke, Edward Meinert, Michael C. Milone, David A. Mitchell, Niraj Muni, Filomena Nappi, Neal H. Nathan, Emanuele Ostuni, Marianthi Papakosta, Simona Paratore, Vincenzo Lorenzo Pascali, Cameron D. Pernia, Benjamin Philipson, Fiona Phillips, James B. Phillips, Nasib Qureshi, Pietro Refolo, Moira Ringo, Matthew Robson, Crystal Ruff, Manuel Schmidt, Matthias Schroff, Michael J. Scott, Michaela Sharpe, Richard L. Sidman, John D. Sinden, Devyn M. Smith, Evan Y. Snyder, Sita Somara, Antonio Gioacchino Spagnolo, Daryl S. Spinner, Kanaka Sridharan, Michael Sullivan, Keith Thompson, Brian T.D. Tobe, Alain A. Vertès, Michael D. West, Cynthia Wilkins-Port, Burghardt Wittig, Aidong Yang, Jie Zhang, Mark C. Zimmerman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::557c2ce10a659280ef90bb6618f8deb1
https://doi.org/10.1016/b978-0-12-812034-7.01002-5
https://doi.org/10.1016/b978-0-12-812034-7.01002-5
Autor:
Dustin R. Wakeman, Nirmalya Ghosh, Amy Plaia, Nejmi Dilmac, Walter D. Niles, Richard E. Hartman, Ruslan Nuryyev, Evan Y. Snyder, Neal H. Nathan, Melissa S. Dulcich, Alena Yusof, Richard L. Sidman, Beatriz Tone, Stephen Ashwal, Janessa B Law, Cameron D. Pernia, Andre Obenaus
Publikováno v:
Cell Reports. 31:107622
To date, no stem cell therapy has been directed to specific recipients-and, conversely, withheld from others-based on a clinical or molecular profile congruent with that cell's therapeutic mechanism-of-action (MOA) for that condition. We address this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c96e8583aa13ce26014189dafe35a5
https://doi.org/10.1016/j.celrep.2020.107622
https://doi.org/10.1016/j.celrep.2020.107622