Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Cameron D Freeman"'
Autor:
Anna K. Cook, Kelsey M. Greathouse, Phaedra N. Manuel, Noelle H. Cooper, Juliana M. Eberhardt, Cameron D. Freeman, Audrey J. Weber, Jeremy H. Herskowitz, Andrew E. Arrant
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-5 (2024)
Abstract Loss-of-function mutations in the progranulin (GRN) gene are an autosomal dominant cause of Frontotemporal Dementia (FTD). These mutations typically result in haploinsufficiency of the progranulin protein. Grn +/– mice provide a model for
Externí odkaz:
https://doaj.org/article/dcc01e54cc45449c9600e182fdd786bb
Autor:
Audrey J. Weber, Ashley B. Adamson, Kelsey M. Greathouse, Julia P. Andrade, Cameron D. Freeman, Jung Vin Seo, Rosaria J. Rae, Courtney K. Walker, Jeremy H. Herskowitz
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-19 (2021)
Abstract Rho-associated kinase isoform 2 (ROCK2) is an attractive drug target for several neurologic disorders. A critical barrier to ROCK2-based research and therapeutics is the lack of a mouse model that enables investigation of ROCK2 with spatial
Externí odkaz:
https://doaj.org/article/4e3a6b68158042169c1a16a3a1c2db46
Autor:
Courtney K Walker, Kelsey M Greathouse, Jennifer J Tuscher, Eric B Dammer, Audrey J Weber, Evan Liu, Kendall A Curtis, Benjamin D Boros, Cameron D Freeman, Jung Vin Seo, Raksha Ramdas, Cheyenne Hurst, Duc M Duong, Marla Gearing, Charles F Murchison, Jeremy J Day, Nicholas T Seyfried, Jeremy H Herskowitz
Publikováno v:
The Journal of Neuroscience. :JN-RM
Proteomic studies utilizing postmortem human brain tissue samples have yielded robust assessments of the aging and neurodegenerative disease(s) proteomes. While these analyses provide lists of molecular alterations in human conditions, like Alzheimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7422eed01e309d618f32cf0a54bc7bd
https://doi.org/10.1523/jneurosci.2102-22.2023
https://doi.org/10.1523/jneurosci.2102-22.2023
Autor:
Courtney K. Walker, Kelsey M. Greathouse, Evan Liu, Hamad M. Muhammad, Benjamin D. Boros, Cameron D. Freeman, Jung Vin Seo, Jeremy H. Herskowitz
Publikováno v:
Neuroscience. 498
Dendritic spines are small protrusions on dendrites that serve as the postsynaptic site of the majority of excitatory synapses. These structures are important for normal synaptic transmission, and alterations in their density and morphology have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc456b374ae7a867a18bfd6615a53623
https://pubmed.ncbi.nlm.nih.gov/35752428
https://pubmed.ncbi.nlm.nih.gov/35752428