Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Cameron Abrams"'
Autor:
Mehdi Benlarbi, Shilei Ding, Étienne Bélanger, Alexandra Tauzin, Raphaël Poujol, Halima Medjahed, Omar El Ferri, Yuxia Bo, Catherine Bourassa, Julie Hussin, Judith Fafard, Marzena Pazgier, Inès Levade, Cameron Abrams, Marceline Côté, Andrés Finzi
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT The continued evolution of severe acute respiratory syndrome 2 (SARS-CoV-2) requires persistent monitoring of its subvariants. Omicron subvariants are responsible for the vast majority of SARS-CoV-2 infections worldwide, with XBB and BA.2.86
Externí odkaz:
https://doaj.org/article/df2d55c283fd4b6a8524d3f74e18d6e6
Autor:
Shilei Ding, William D. Tolbert, Huile Zhu, Daniel Lee, Lorie Marchitto, Tyler Higgins, Xuchen Zhao, Dung Nguyen, Rebekah Sherburn, Jonathan Richard, Gabrielle Gendron-Lepage, Halima Medjahed, Mohammadjavad Mohammadi, Cameron Abrams, Marzena Pazgier, Amos B. Smith, Andrés Finzi
Publikováno v:
Viruses, Vol 15, Iss 5, p 1185 (2023)
The ability of the HIV-1 accessory proteins Nef and Vpu to decrease CD4 levels contributes to the protection of infected cells from antibody-dependent cellular cytotoxicity (ADCC) by preventing the exposure of Env vulnerable epitopes. Small-molecule
Externí odkaz:
https://doaj.org/article/52e7e420c9a942b2be25abc6e48e553d
Autor:
Alon Herschhorn, Christopher Gu, Francesca Moraca, Xiaochu Ma, Mark Farrell, Amos B. Smith, Marie Pancera, Peter D. Kwong, Arne Schön, Ernesto Freire, Cameron Abrams, Scott C. Blanchard, Walther Mothes, Joseph G. Sodroski
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Binding of viral envelope glycoproteins (Env) to the host cell CD4 receptor mediates HIV-1 entry. Here, the authors develop compounds that inhibit the CD4-induced conformational changes in Env and show that the gp120 β20-β21 element is a key regula
Externí odkaz:
https://doaj.org/article/b36161e14e3f46feaa6eadd812d25c74
Autor:
Cameron Abrams, Giovanni Bussi
Publikováno v:
Entropy, Vol 16, Iss 1, Pp 163-199 (2013)
We review a selection of methods for performing enhanced sampling in molecular dynamics simulations. We consider methods based on collective variable biasing and on tempering, and offer both historical and contemporary perspectives. In collective-var
Externí odkaz:
https://doaj.org/article/83722de07d664b34873aab014ab845b8
Autor:
Alon Herschhorn, Christopher Gu, Francesca Moraca, Xiaochu Ma, Mark Farrell, Amos B. Smith, Marie Pancera, Peter D. Kwong, Arne Schön, Ernesto Freire, Cameron Abrams, Scott C. Blanchard, Walther Mothes, Joseph G. Sodroski
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this Article contained an error in the spelling of the author Amos B. Smith, III, which was incorrectly given as Amos B. SmithIII. This has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/674c8bbdf17a40eb8d6bf661351a14be
Autor:
Christopher Fritschi, Saumya Anang, Zhen Gong, Mohammadjavad Mohammadi, Jonathan Richard, Catherine Bourassa, Kenny T. Severino, Hannah Richter, Derek Yang, Hung-Ching Chen, Ta-Jung Chiu, Michael Seaman, Navid Madani, Cameron Abrams, Andrés Finzi, Wayne A. Hendrickson, Joseph Sodroski, Amos B. Smith
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Binding to the host cell receptors, CD4 and CCR5/CXCR4, triggers large-scale conformational changes in the human immunodeficiency virus (HIV-1) envelope glycoprotein (Env) trimer [(gp120/gp41)3] that promote virus entry into the cell. CD4-mimetic com
Autor:
Giulio Alberini, S. Alexis Paz, Beatrice Corradi, Cameron Abrams, Fabio Benfenati, Luca Maragliano
The recent determination of cryo-EM structures of voltage-gated sodium (Nav)channels has revealed many details of these proteins. However, knowledge of ionic permeation through the Nav pore remains limited. In this work, we performed atomistic molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d64c9527b1ca2673a178aad9d3efc22
https://doi.org/10.1101/2022.09.29.509656
https://doi.org/10.1101/2022.09.29.509656
Autor:
Shilei Ding, Irfan Ullah, Shang Yu Gong, Jonathan R. Grover, Mohammadjavad Mohammadi, Yaozong Chen, Dani Vézina, Guillaume Beaudoin-Bussières, Vijay Tailor Verma, Guillaume Goyette, Fleur Gaudette, Jonathan Richard, Derek Yang, Amos B. Smith, Marzena Pazgier, Marceline Côté, Cameron Abrams, Priti Kumar, Walther Mothes, Pradeep D. Uchil, Andrés Finzi, Christian Baron
Publikováno v:
bioRxiv
SummarySARS-CoV-2 infection of host cells starts by binding of the Spike glycoprotein (S) to the ACE2 receptor. The S-ACE2 interaction is a potential target for therapies against COVID-19 as demonstrated by the development of immunotherapies blocking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e127fee33a9acf34b0b0671c6f21e1
https://doi.org/10.1101/2022.02.03.479007
https://doi.org/10.1101/2022.02.03.479007
Publikováno v:
Computational Materials Science. 207:111264
Autor:
Ming Huang, Cameron Abrams
Publikováno v:
Macromolecular Theory and Simulations. 28:1970011