Zobrazeno 1 - 10
of 12 495
pro vyhledávání: '"Cameron, D A"'
This work presents a novel lattice-based methodology for incorporating multidimensional constraints into continuous decision variables within a genetic algorithm (GA) framework. The proposed approach consolidates established transcription techniques
Externí odkaz:
http://arxiv.org/abs/2410.12188
Autor:
Bikash Chandra Swain, Pascale Sarkis, Vanessa Ung, Sabrina Rousseau, Laurent Fernandez, Ani Meltonyan, V. Esperance Aho, Davide Mercadante, Cameron D. Mackereth, Mikayel Aznauryan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Eukaryotic translation initiation factor eIF4B is required for efficient cap-dependent translation, it is overexpressed in cancer cells, and may influence stress granule formation. Due to the high degree of intrinsic disorder, eIF4B is rarel
Externí odkaz:
https://doaj.org/article/faf2eb2ccf9f4538a76de5ae612d6eb5
Autor:
Andrew J Sweatt, Cameron D Griffiths, Sarah M Groves, B Bishal Paudel, Lixin Wang, David F Kashatus, Kevin A Janes
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 11, Pp 1230-1256 (2024)
Abstract Protein copy numbers constrain systems-level properties of regulatory networks, but proportional proteomic data remain scarce compared to RNA-seq. We related mRNA to protein statistically using best-available data from quantitative proteomic
Externí odkaz:
https://doaj.org/article/a78905cf20e7454b93c42dc6ce895a86
Autor:
Cameron D. Bullen, John Driscoll, Jenn Burt, Tiffany Stephens, Margot Hessing-Lewis, Edward J. Gregr
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Seaweed farming is widely promoted as an approach to mitigating climate change despite limited data on carbon removal pathways and uncertainty around benefits and risks at operational scales. We explored the feasibility of climate change mit
Externí odkaz:
https://doaj.org/article/f9cc35da98444cb19bfaedd35a7afda6
Autor:
Joseph T. Flannery-Sutherland, Cameron D. Crossan, Corinne E. Myers, Austin J. W. Hendy, Neil H. Landman, James D. Witts
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Palaeontologists have long sought to explain the diversification of individual clades to whole biotas at global scales. Advances in our understanding of the spatial distribution of the fossil record through geological time, however, has demo
Externí odkaz:
https://doaj.org/article/e3594c34409649e3817eb6a21bd5ca82
Autor:
Anna K. Cook, Kelsey M. Greathouse, Phaedra N. Manuel, Noelle H. Cooper, Juliana M. Eberhardt, Cameron D. Freeman, Audrey J. Weber, Jeremy H. Herskowitz, Andrew E. Arrant
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-5 (2024)
Abstract Loss-of-function mutations in the progranulin (GRN) gene are an autosomal dominant cause of Frontotemporal Dementia (FTD). These mutations typically result in haploinsufficiency of the progranulin protein. Grn +/– mice provide a model for
Externí odkaz:
https://doaj.org/article/dcc01e54cc45449c9600e182fdd786bb
Publikováno v:
Cement, Vol 17, Iss , Pp 100110- (2024)
The elastic stiffness of bulk concrete materials results from the complex interaction of aggregates, voids, and hydrated cement (which can have multiple hardened phases at multiple length scales). Given the complexities associated with understanding
Externí odkaz:
https://doaj.org/article/2f66ce38c4454414bf8506fe43f369fe
Autor:
Sweatt, Andrew J1 (AUTHOR), Griffiths, Cameron D1 (AUTHOR), Groves, Sarah M1 (AUTHOR), Paudel, B Bishal1 (AUTHOR), Wang, Lixin1 (AUTHOR), Kashatus, David F2 (AUTHOR), Janes, Kevin A1,3 (AUTHOR) kjanes@virginia.edu
Publikováno v:
Molecular Systems Biology. Nov2024, Vol. 20 Issue 11, p1230-1256. 27p.
Autor:
Steven J. Granger, Victor May, Sayamwong E. Hammack, Eylül Akman, Sydney A. Jobson, Elizabeth A. Olson, Cameron D. Pernia, Nikos P. Daskalakis, Caitlin Ravichandran, William A. Carlezon, Kerry J. Ressler, Scott L. Rauch, Isabelle M. Rosso
Publikováno v:
European Journal of Psychotraumatology, Vol 15, Iss 1 (2024)
ABSTRACTIntroduction: Pituitary adenylate cyclase-activating polypeptide (PACAP) regulates plasticity in brain systems underlying arousal and memory and is associated with posttraumatic stress disorder (PTSD). Research in animal models suggests that
Externí odkaz:
https://doaj.org/article/0310fd5d6f434b3ea710bf48d02bfeb8