Drug-induced cholestasis (DIC) predictions based on in vitro inhibition of major bile acid clearance mechanisms.

Autor: Kastrinou-Lampou V; Pharmacokinetic Sciences, BioMedical Research, Novartis, Basel, Switzerland.; Preclinical Safety, BioMedical Research, Novartis, Basel, Switzerland.; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Rodríguez-Pérez R; Pharmacokinetic Sciences, BioMedical Research, Novartis, Basel, Switzerland., Poller B; Pharmacokinetic Sciences, BioMedical Research, Novartis, Basel, Switzerland., Huth F; Pharmacokinetic Sciences, BioMedical Research, Novartis, Basel, Switzerland., Schadt HS; Preclinical Safety, BioMedical Research, Novartis, Basel, Switzerland., Kullak-Ublick GA; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Mechanistic Safety, CMO and Patient Safety, Global Drug Development, Novartis, Basel, Switzerland., Arand M; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Camenisch G; Pharmacokinetic Sciences, BioMedical Research, Novartis, Basel, Switzerland. gian.camenisch@novartis.com.

Publikováno v: Archives of toxicology [Arch Toxicol] 2024 Nov 14. Date of Electronic Publication: 2024 Nov 14.

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UP62 - Morphometric analysis of epithelial bladder cancer on tissue and cellular scale

Autor: Lampart, F., Vetter, R., Yamauchi, K., Runser, S., Wang, Y., Murelis, A., Meer, F., Stromeier, N., Hussherr, M-D., Camenisch, G., Rentsch, C., Le Magnen, C., Müller, D.J., Bubendorf, L., Iber, D.

Publikováno v: In European Urology Open Science October 2023 56 Supplement 1:S83-S83

Genetic variance in fitness indicates rapid contemporary adaptive evolution in wild animals.

Autor: Bonnet T; Research School of Biology, Australian National University, Canberra, ACT, Australia., Morrissey MB; School of Biology, University of St Andrews, St Andrews, Fife, UK., de Villemereuil P; Institut de Systématique, Évolution, Biodiversité (ISYEB), École Pratique des Hautes Études, PSL, MNHN, CNRS, SU, UA, Paris, France.; School of Biological Sciences, University of Auckland, Auckland, New Zealand., Alberts SC; Departments of Biology and Evolutionary Anthropology, Duke University, Durham, NC, USA., Arcese P; Forest and Conservation Sciences, University of British Columbia, Vancouver, British Columbia, Canada., Bailey LD; Departments of Evolutionary Ecology and Evolutionary Genetics, Leibniz Institute for Zoo and Wildlife Research, Berlin, Germany., Boutin S; Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada., Brekke P; Institute of Zoology, Zoological Society of London, Regents Park, London, UK., Brent LJN; Centre for Research in Animal Behaviour, University of Exeter, Penryn, UK., Camenisch G; Department of Evolutionary Biology and Environmental Studies, University of Zurich, Zurich, Switzerland., Charmantier A; Centre d'Écologie Fonctionnelle et Évolutive, Université de Montpellier, CNRS, EPHE, IRD, Montpellier, France., Clutton-Brock TH; Department of Zoology, University of Cambridge, Cambridge, UK.; Mammal Research Institute, University of Pretoria, Pretoria, South Africa., Cockburn A; Research School of Biology, Australian National University, Canberra, ACT, Australia., Coltman DW; Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada., Courtiol A; Departments of Evolutionary Ecology and Evolutionary Genetics, Leibniz Institute for Zoo and Wildlife Research, Berlin, Germany., Davidian E; Departments of Evolutionary Ecology and Evolutionary Genetics, Leibniz Institute for Zoo and Wildlife Research, Berlin, Germany., Evans SR; Edward Grey Institute, Department of Zoology, University of Oxford, Oxford, UK.; Department of Ecology and Genetics, Uppsala University, Uppsala, Sweden.; Centre for Ecology and Conservation, University of Exeter, Penryn, UK., Ewen JG; Institute of Zoology, Zoological Society of London, Regents Park, London, UK., Festa-Bianchet M; Département de Biologie, Université de Sherbrooke, Sherbrooke, Québec, Canada., de Franceschi C; Centre d'Écologie Fonctionnelle et Évolutive, Université de Montpellier, CNRS, EPHE, IRD, Montpellier, France., Gustafsson L; Department of Ecology and Genetics, Uppsala University, Uppsala, Sweden., Höner OP; Departments of Evolutionary Ecology and Evolutionary Genetics, Leibniz Institute for Zoo and Wildlife Research, Berlin, Germany., Houslay TM; Department of Zoology, University of Cambridge, Cambridge, UK.; Centre for Ecology and Conservation, University of Exeter, Penryn, UK., Keller LF; Department of Evolutionary Biology and Environmental Studies, University of Zurich, Zurich, Switzerland.; Zoological Museum, University of Zurich,, Zurich, Switzerland., Manser M; Department of Evolutionary Biology and Environmental Studies, University of Zurich, Zurich, Switzerland.; Mammal Research Institute, University of Pretoria, Pretoria, South Africa., McAdam AG; Department of Ecology and Evolutionary Biology, University of Colorado, Boulder, CO, USA., McLean E; Biology Department, Oxford College, Emory University, Oxford, GA, USA., Nietlisbach P; School of Biological Sciences, Illinois State University, Normal, IL, USA., Osmond HL; Research School of Biology, Australian National University, Canberra, ACT, Australia., Pemberton JM; Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK., Postma E; Centre for Ecology and Conservation, University of Exeter, Penryn, UK., Reid JM; Centre for Biodiversity Dynamics, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.; School of Biological Sciences, University of Aberdeen, Aberdeen, UK., Rutschmann A; School of Biological Sciences, University of Auckland, Auckland, New Zealand., Santure AW; School of Biological Sciences, University of Auckland, Auckland, New Zealand., Sheldon BC; Edward Grey Institute, Department of Zoology, University of Oxford, Oxford, UK., Slate J; Ecology and Evolutionary Biology, School of Biosciences, University of Sheffield, Sheffield, UK., Teplitsky C; Centre d'Écologie Fonctionnelle et Évolutive, Université de Montpellier, CNRS, EPHE, IRD, Montpellier, France., Visser ME; Department of Animal Ecology, Netherlands Institute of Ecology (NIOO-KNAW), Wageningen, Netherlands., Wachter B; Departments of Evolutionary Ecology and Evolutionary Genetics, Leibniz Institute for Zoo and Wildlife Research, Berlin, Germany., Kruuk LEB; Research School of Biology, Australian National University, Canberra, ACT, Australia.; Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK.

Publikováno v: Science (New York, N.Y.) [Science] 2022 May 27; Vol. 376 (6596), pp. 1012-1016. Date of Electronic Publication: 2022 May 26.

A robust sequencing assay of a thousand amplicons for the high-throughput population monitoring of Alpine ibex immunogenetics.

Autor: Kessler C; Laboratory of Evolutionary Genetics, Institute of Biology, University of Neuchâtel, Neuchâtel, Switzerland., Brambilla A; Department of Evolutionary Biology and Environmental Studies, University of Zürich, Zürich, Switzerland.; Alpine Wildlife Research Center, Gran Paradiso National Park, Italy., Waldvogel D; Department of Evolutionary Biology and Environmental Studies, University of Zürich, Zürich, Switzerland., Camenisch G; Department of Evolutionary Biology and Environmental Studies, University of Zürich, Zürich, Switzerland., Biebach I; Department of Evolutionary Biology and Environmental Studies, University of Zürich, Zürich, Switzerland., Leigh DM; Department of Evolutionary Biology and Environmental Studies, University of Zürich, Zürich, Switzerland.; WSL Swiss Federal Research Institute, Birmensdorf, Switzerland., Grossen C; Department of Evolutionary Biology and Environmental Studies, University of Zürich, Zürich, Switzerland., Croll D; Laboratory of Evolutionary Genetics, Institute of Biology, University of Neuchâtel, Neuchâtel, Switzerland.

Publikováno v: Molecular ecology resources [Mol Ecol Resour] 2022 Jan; Vol. 22 (1), pp. 66-85. Date of Electronic Publication: 2021 Jul 07.